neurotic1234
02-14-2010, 12:41 AM
Hi,
Iam trying to analyse experimental data that I have. The experiment is designed to assess the effect of a disease condition on spatial memory using mice. There are 3 groups - No disease (-ve control), Drug that mimics the disease (+ve control), Disease. The performance of mice (distance to target) is measured daily using 8 trials (with the target at a different position during each trial) and repeated over 7 days. There was no crossover between the groups- each mouse was assigned only to one of the 3 groups and subjected to the trials daily (i.e the study is nested?).
I want to analyse the effect of both trial and day on the groups and hopefully find that the disease and +ve control groups perform worse than the -ve control group over trials or days or both.
I think that I should use a repeated measures ANOVA with trial and day as within subject effects and group as between subject effects. In the results that come up with this analysis on SPSS, what should I look at to get the answer to my question ? There are different things like test of sphericity, tests of within subject effects , within subject contrasts, between subject effects etc..what do each of these mean in the context of my experiment?
I'm new to this field and hence the doubts!
Thanks!
Iam trying to analyse experimental data that I have. The experiment is designed to assess the effect of a disease condition on spatial memory using mice. There are 3 groups - No disease (-ve control), Drug that mimics the disease (+ve control), Disease. The performance of mice (distance to target) is measured daily using 8 trials (with the target at a different position during each trial) and repeated over 7 days. There was no crossover between the groups- each mouse was assigned only to one of the 3 groups and subjected to the trials daily (i.e the study is nested?).
I want to analyse the effect of both trial and day on the groups and hopefully find that the disease and +ve control groups perform worse than the -ve control group over trials or days or both.
I think that I should use a repeated measures ANOVA with trial and day as within subject effects and group as between subject effects. In the results that come up with this analysis on SPSS, what should I look at to get the answer to my question ? There are different things like test of sphericity, tests of within subject effects , within subject contrasts, between subject effects etc..what do each of these mean in the context of my experiment?
I'm new to this field and hence the doubts!
Thanks!