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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. HLM Unit Specific vs. Population Average Model

    I am using HLM to do a 2 level longitudinal analysis of change in firearm background check denial rate. The denial rate per 100,000 is the outcome....

    Started by muelledg‎, 02-12-2016 02:11 PM
    • Replies: 1
    • Views: 77
    02-12-2016, 07:28 PM Go to last post
  2. Post Median Fold Change and Interquartile Range. 2 non-normal non-paired groups.

    I have a query concerning data presentation using biological data. I would like to present the median fold change between a control and test...

    Started by phdmedsci‎, 02-12-2016 01:13 PM
    interquartile range, median fold change, medical science, non-normal distribution
    • Replies: 0
    • Views: 55
    02-12-2016, 01:13 PM Go to last post
  3. Prospective study. What test would be appropriate?

    Hey there! I am practicing on these data I have and I want to apply a statistical test. I want to compare 2 treatments: evolution and incidence...

    Started by Flaviviridae‎, 02-10-2016 12:14 PM
    • Replies: 6
    • Views: 171
    02-11-2016, 03:31 PM Go to last post
  4. Ploting continuous caracter on a phylogenetic tree

    Hi, I study comparative biology and have been trying to estimate ancestral character states for continuous characters using the package phytools. ...

    Started by jessicafratani‎, 02-10-2016 01:42 PM
    • Replies: 4
    • Views: 129
    02-10-2016, 05:59 PM Go to last post
  5. Diagnostic accuracy of two methods tested on longitudinal data/repeated measurements

    To compare two imaging rating methods in detecting growth (ordinal variable + , = , - ) we compared serial MRI's with both methods. We have for...

    Started by SophieBel‎, 02-09-2016 01:24 PM
    • Replies: 1
    • Views: 98
    02-09-2016, 06:10 PM Go to last post
  6. Rows or columns?

    In a clinical statistics workshop we were given this question? Can anyone help me, I've been tearing my hair about it: A case control study of...

    Started by gillis‎, 02-08-2016 03:42 PM
    • Replies: 1
    • Views: 128
    02-09-2016, 04:22 AM Go to last post
  7. Please help me! I am stuck choosing which model to use! :(

    Hello! I have been reading so much about stats that I am a bit confused now.. I have samples from an experiment in which I have counted cells. So I...

    Started by Cats‎, 02-08-2016 08:56 PM
    multilevel modeling, nested
    • Replies: 1
    • Views: 142
    02-09-2016, 01:23 AM Go to last post
  8. Which test should I use?

    Hello There: I am wondering which test to use for this question: Does the involvement in child welfare in an participants’ life increase the...

    Started by gbgb‎, 01-28-2016 10:09 PM
    • Replies: 2
    • Views: 198
    02-07-2016, 01:35 PM Go to last post
  9. Help

    Ok, so here is my problem, I have a patient list of 300 patients each with unique identifiers like age, sex, race. Each patient is numbered 0001,...

    Started by iamrico00‎, 02-04-2016 02:06 PM
    • Replies: 0
    • Views: 168
    02-04-2016, 02:06 PM Go to last post
  10. Pre-post test for same group (no control), controlling for confounding

    Which Test to use & How to use in SPSS? MY situation: In a single group, pre post intervention scenario, i wan to test whether the change in...

    Started by HBS‎, 02-03-2016 01:40 PM
    • Replies: 4
    • Views: 244
    02-04-2016, 05:00 AM Go to last post
  11. Averaging and comparing mean values across studies

    I am having a statistical problem that falls into two parts: (!) I have several literature reports on studies that have investigated the effect of...

    Started by AVoelp‎, 02-03-2016 09:04 AM
    • Replies: 0
    • Views: 105
    02-03-2016, 09:04 AM Go to last post
  12. Back transformation for log-transformed variables in Cox regression

    I have to perform a meta-analysis. My problem is that in a number of studies, the HRs for the explanatory variable are reported for the log...

    Started by Dimitrie‎, 02-02-2016 04:20 AM
    • Replies: 0
    • Views: 122
    02-02-2016, 04:20 AM Go to last post
  13. Question- student paired sample t test, wilcoxon signed rank test

    Hi, I have samples that are not expected to be normally distributed, I treat them with and without a compound and perform statistical analysis. I...

    Started by AggieTheBird‎, 01-26-2016 03:28 AM
    • Replies: 3
    • Views: 288
    01-31-2016, 02:58 AM Go to last post
  14. Measuring disease severity of PAIRS of eyes between treated and untreated groups

    Dear forum. Would someone please beable to provide me some advice on which statistical analysis to apply to an aspect of my PhD data... I am...

    Started by CrossRoe‎, 01-29-2016 09:06 AM
    eyes, paired samples
    • Replies: 3
    • Views: 255
    01-29-2016, 10:01 AM Go to last post
  15. Post N of 1 study looking at complex phenotypes and SNPs

    Hi All, I have a complicated question and can't find a resource that answers it comprehensively. I'm designing a study looking for linkage between a...

    Started by keri‎, 01-27-2016 05:49 PM
    biostatistics, complex disease, complex variables, linear regression, snp
    • Replies: 0
    • Views: 136
    01-27-2016, 05:49 PM Go to last post
  16. Equivalence limit in Bioequivalence studies

    Hi All, Need this input from you..in bioequivalence studies, can we use the equivalence limit of (-0.2) instead of (+0.2) since the range is...

    Started by charan.kumar.kj@gmail.com‎, 01-25-2016 02:52 AM
    • Replies: 1
    • Views: 174
    01-25-2016, 04:18 AM Go to last post
  17. Smile Intention to treat analysis and estimating loss to follow up

    Hi guys, Doing my MSc in Clinical Trials and after looking at a research paper I am stumped about something... The authors have stated that...

    Started by clinicaltrialsnewb‎, 01-23-2016 11:34 PM
    • Replies: 2
    • Views: 222
    01-24-2016, 11:55 AM Go to last post
  18. question about survival analysis and late entry data

    I have a large ongoing national longitudinal survey data. The original cohort contains people between age 51-61 in 1992. Since the beginning of the...

    Started by sunny3333‎, 01-19-2016 02:05 PM
    • Replies: 3
    • Views: 277
    01-20-2016, 08:03 AM Go to last post
  19. Calculating control group in chi square test

    I'm trying to compare the prevalence rate of autism in offspring of mothers with and without gestational diabetes. I gathered data from 1000 women, 8...

    Started by Michalus‎, 01-15-2016 09:11 PM
    • Replies: 2
    • Views: 455
    01-16-2016, 08:48 AM Go to last post
  20. Multivariate analysis?

    I am working on designing a research project and I am trying to determine the appropriate statistical analysis. My research project (simplified...

    Started by thesamrag‎, 01-12-2016 07:45 PM
    • Replies: 1
    • Views: 300
    01-13-2016, 11:35 AM Go to last post
  21. Minimum control size for determining effectiveness of treatment

    So the following scenario I have a treatment that I know to be effective, but I want to determine precisely how effective it in a (large) group...

    Started by xandalorian‎, 01-08-2016 08:27 AM
    2 Pages
    1 2
    control group, experiment design, significance, test
    • Replies: 15
    • Views: 448
    01-08-2016, 04:24 PM Go to last post
  22. Sample size calculation for cross-sectional survey (2 Time points)

    I am working on a study design for a study to determine behaviors and structural barriers to health seeking at baseline for HIV negative young women...

    Started by kabalaandrew‎, 01-08-2016 05:43 AM
    cross-sectional, sample design, sample size, study design
    • Replies: 0
    • Views: 145
    01-08-2016, 05:43 AM Go to last post
  23. Kaplan Meier Curves With Repeat Events? Is it Possible?

    This may be a stupid question, but: can you construct Kaplan-Meier curves for repeat event data? Or should I limit each individual to occurrence of...

    Started by lauraemiliana‎, 01-05-2016 02:25 AM
    kaplan meier, kaplan-meier, repeat measures, survival, survival analysis
    • Replies: 1
    • Views: 251
    01-05-2016, 07:42 AM Go to last post
  24. Model selection versus variable selection

    Hello, For my research I have 3 sets of different data. The aim is to evaluate the added prognostic value for survival of 2 sets to a baseline model...

    Started by noob‎, 12-25-2015 06:00 PM
    • Replies: 3
    • Views: 1,004
    01-02-2016, 07:10 PM Go to last post
  25. Study Design for assessing New Clinical Sign where gold standard is not available

    Hi! I am looking for some guidance as to what statistical tests I would need to do to know the significance of a study. The situation is this: ...

    Started by cielo‎, 01-02-2016 09:54 AM
    • Replies: 1
    • Views: 204
    01-02-2016, 11:08 AM Go to last post
  26. Site x species matrix and enviromental Variables. Which tests should I use

    Hello Talkstats Forum, I am currently doing my study with the theme: Effects of farming type and landscape density on carabid diversity and...

    Started by Carabid‎, 12-19-2015 06:34 AM
    cca, dca, environment variables, species data
    • Replies: 1
    • Views: 400
    12-22-2015, 12:07 PM Go to last post
  27. MaxT corrected p value

    Hi all, I am trying to permute data and return a maxT p value to adjust for FWER. I have an example of data: SNP1 p value= 0.02 SNP1...

    Started by Evied‎, 12-22-2015 08:22 AM
    maxt, p value, permutation
    • Replies: 0
    • Views: 163
    12-22-2015, 08:22 AM Go to last post
  28. Inquiry about means comparision of factorial experiments

    urgent and important dear, friends I need clarification about comparison between interaction of treatments. If I've factorial experiment (2*3) with...

    Started by hazemalashwal‎, 12-21-2015 10:12 AM
    • Replies: 0
    • Views: 223
    12-21-2015, 10:12 AM Go to last post
  29. Exclamation Help with Biostats Hw question

    The research team has considered your answers to the above. They’ve narrowed their interest to two outcomes (for now): Number of episodes of early...

    Started by 303oselim‎, 12-18-2015 08:00 PM
    biostats, stats
    • Replies: 0
    • Views: 221
    12-18-2015, 08:00 PM Go to last post
  30. Need help choosing a statistical method/model

    Hello, I am currently doing a study on the defensive behavior of the European Grass Snake, and I was hoping someone could help me figure out...

    Started by brittany‎, 06-23-2015 10:44 AM
    anova ecology biology, help!, linear mixed model, logistic regression, nested anova
    • Replies: 2
    • Views: 500
    12-18-2015, 07:29 PM Go to last post
  31. Trying to analyze aggregated data

    Hi, I would like to know how it would be possible to make a t-test with aggregated data on SPSS or R. My dataset looks like this: ...

    Started by Sarou‎, 12-17-2015 12:14 PM
    aggregated data, biostatistics, spss, t-tests
    • Replies: 3
    • Views: 309
    12-17-2015, 03:57 PM Go to last post
  32. Agreement between raters who record the frequency at which they would choose options

    Say I have 5 raters and 6 choices. For each choice, each rater records a frequency from 0 to 100: the percentage of time they would choose that...

    Started by emogene‎, 12-17-2015 10:01 AM
    • Replies: 0
    • Views: 151
    12-17-2015, 10:01 AM Go to last post
  33. what is the objective of yeast dataset?

    Recently, l started working on yeast data (http://archive.ics.uci.edu/ml/datasets/Yeast). My goal is to do an exploratory statistics upon these data,...

    Started by montecarlo‎, 12-16-2015 06:54 AM
    data analysis, pca analysis, statistical analysis
    • Replies: 1
    • Views: 226
    12-16-2015, 05:13 PM Go to last post
  34. What method shpuld i use?

    i'm confuse how to analyze my data. 1. i have 2 independent factor and 4 dependent factor, with unexpected count high to 75%, what analytical method...

    Started by Denxe‎, 12-16-2015 10:18 AM
    • Replies: 0
    • Views: 167
    12-16-2015, 10:18 AM Go to last post
  35. Checking my approach - Mann whitney

    Hi everyone I was wondering if I had used the correct approach to analyse my data. I have four groups of people answering a survey and taking part...

    Started by Statistics help‎, 12-14-2015 05:51 AM
    kruskall-wallis, mann whitney u test
    • Replies: 2
    • Views: 326
    12-15-2015, 05:16 PM Go to last post
  36. Analyzing dataset with zeros

    I am analyzing a dataset on offspring production in fruit flies that have mated with individuals from their own population or another population. So...

    Started by Jbon‎, 12-03-2015 12:20 PM
    • Replies: 5
    • Views: 528
    12-14-2015, 09:07 AM Go to last post
  37. GLMM versus logistic regression if no random effects

    Dear all, I am working with binary data and I was wondering: in a model that does not include any random effect (only fixed effect), ...

    Started by nicoladiggi‎, 12-13-2015 05:46 AM
    • Replies: 5
    • Views: 404
    12-13-2015, 06:09 PM Go to last post
  38. Post Which statistical test?

    Hey there, I have an experiment involving 2 groups of people: a control and a test. There were 30 different people in each group and the test group...

    Started by AC82‎, 12-12-2015 10:36 AM
    which statistical
    • Replies: 0
    • Views: 245
    12-12-2015, 10:36 AM Go to last post
  39. Does this graph shows a normal distribution ?

    Hello, I am a newbie in Biostatistics field... I would be so thankful if you tell me if below chart has a normal distribution or not and why ? ...

    Started by A.Chakery‎, 11-21-2015 03:16 PM
    • Replies: 4
    • Views: 567
    12-10-2015, 11:32 AM Go to last post
  40. Question Funnel plot - is the funnel overlay just a visual tool or is it precisely calculated?

    I'm trying to create a funnel plot, and I'm wondering if there's a rule behind the funnel shape - are the two slanted lines simply meant to cross the...

    Started by j4ne‎, 12-10-2015 06:16 AM
    • Replies: 1
    • Views: 238
    12-10-2015, 09:12 AM Go to last post
  41. Direct standardization - age

    Hi I have data with 250 events during an 10-year period. I have calculated incidence rates based on the general population. I now want to...

    Started by Laurjo‎, 12-10-2015 04:47 AM
    age groups, standardization, strata
    • Replies: 0
    • Views: 195
    12-10-2015, 04:47 AM Go to last post
  42. Red face Help with Cox Regression

    Hi all, it's my first time here, but I hope to be able to contribute to other threads soon. I'm working on a dataset at the moment, and need a...

    Started by researchworker‎, 12-08-2015 10:10 AM
    • Replies: 10
    • Views: 559
    12-09-2015, 03:49 PM Go to last post
  43. Which statistical test would you suggest in this case?

    Hello to everyone, I have a question on how to choose the best statistical test to see whether what I have found is significant or not. That is...

    Started by Alessiaa‎, 12-09-2015 11:55 AM
    • Replies: 0
    • Views: 244
    12-09-2015, 11:55 AM Go to last post
  44. Test for healthy and sick organ development

    Hi guys, Quick question: I have data from patients who suffer on some organ failure. Let’s say I have ten organ function measurements over time....

    Started by Stats_Newbie‎, 12-02-2015 10:57 AM
    • Replies: 3
    • Views: 426
    12-05-2015, 02:51 PM Go to last post
  45. Need Help: Kaplan Meier analysis

    Hi I have a large database and have generated KP curves for long term survival but there is not difference in overall/long term survival. Our goal...

    Started by survivinganalysis‎, 11-28-2015 12:07 AM
    • Replies: 1
    • Views: 333
    11-28-2015, 02:56 AM Go to last post
  46. Appropriate p-value correction in two cohort meta-analysis (discovery / validation)

    Dear all, I would like to request your help and opinions on a meta-analysis setup utilizing two completely independent cancer cohorts, where one...

    Started by bontus‎, 11-26-2015 10:31 AM
    dataset integration, fdr, meta analysis, p-value correction, validation
    • Replies: 0
    • Views: 274
    11-26-2015, 10:31 AM Go to last post
  47. Analysis for progression free survival (PFS), and Dose intensities effect on PFS.

    Hi every Body, The project that we are doing is related to a drug that is given to patients having colorectal cancer, after they have failed all...

    Started by sanaullah92‎, 11-18-2015 08:11 PM
    progression free survival
    • Replies: 0
    • Views: 328
    11-18-2015, 08:11 PM Go to last post
  48. Spearman partial correlation corrected for multiple comparisons

    Hi all, I would like to ask you some help about this: Which would be the Bonferroni correction for a Spearman partial correlation controlled by...

    Started by purkinje‎, 11-17-2015 10:27 AM
    spearman bonferroni
    • Replies: 0
    • Views: 278
    11-17-2015, 10:27 AM Go to last post
  49. Data Analysis for Clinical Trials

    For a research module, for my postgraduate degree, I need to design a clinical trial research protocol. I am looking at how safe and effective drug X...

    Started by Joseph551‎, 11-15-2015 02:03 PM
    • Replies: 3
    • Views: 409
    11-16-2015, 03:28 PM Go to last post
  50. Help concerning random forest in R

    Working on a data set with bio markers. This is a classification problem and I'm having some troubles finding any information concerning the process...

    Started by lukketotte‎, 11-16-2015 10:43 AM
    • Replies: 0
    • Views: 219
    11-16-2015, 10:43 AM Go to last post
  51. Need help with spline for clustered data

    Hello everyone, I am a new member on this forum. I am recently running into a problem with analyzing correlated data for a twin study. I am...

    Started by Tiny‎, 11-10-2015 07:19 AM
    • Replies: 0
    • Views: 343
    11-10-2015, 07:19 AM Go to last post
  52. Multiple groups, comparing healthcare costs, problem: excluding specific data [Prism]

    Hi I have cost data for three groups of patients and we want to see if there is a difference in costs before, during and after we implemented a...

    Started by moeveleigh‎, 11-08-2015 08:42 AM
    • Replies: 0
    • Views: 327
    11-08-2015, 08:42 AM Go to last post
  53. Treatment-experiment interactions in multivariate data

    I have a data set of multivariate data (4 treatments, 3 samples per treatment, 14 variables, the variables are concentrations of different...

    Started by Tabita‎, 11-06-2015 04:26 AM
    f-test, multivariate analysis, multivariate data, repeated experiments
    • Replies: 0
    • Views: 274
    11-06-2015, 04:26 AM Go to last post
  54. I need help to analyze this data

    Dear valued experts, I need help in calculating the significance of the following data: Two groups of patients on Rx (A) and (B) I am comparing...

    Started by farahi‎, 11-04-2015 06:35 AM
    • Replies: 0
    • Views: 314
    11-04-2015, 06:35 AM Go to last post
  55. Help! Nursing statistics- wordy problem no one in the class can answer

    Hi everyone! Hoping someone is able to help guide me and my classmates. Our teacher isn't great and will not assist us with this question. Our...

    Started by nursestatsdummy‎, 10-31-2015 12:03 AM
    • Replies: 1
    • Views: 410
    10-31-2015, 12:34 AM Go to last post
  56. What test to run ?

    Hi everybody! I have a small sample of patients that have undergone two interventions and we want to analyze the effect on a specific bloodsample...

    Started by Cak024‎, 10-29-2015 08:25 AM
    • Replies: 0
    • Views: 286
    10-29-2015, 08:25 AM Go to last post
  57. Sample size

    Hello! I need your help to define the sample size of a study. We want to study the effect of a food on the expression of a series of microRNAs...

    Started by Fischer‎, 10-28-2015 08:12 AM
    • Replies: 2
    • Views: 358
    10-29-2015, 05:20 AM Go to last post
  58. Question Pearson's Correlation _ with individual X error and Y error

    Hi all, I have a problem that I can't seem to solve. I don't know how to account for the individual measurement error in a Pearson's correlation r...

    Started by wiredalchemist‎, 10-26-2015 09:49 PM
    • Replies: 1
    • Views: 304
    10-26-2015, 09:53 PM Go to last post
  59. Smile Need statistician

    Hi Gastrodoc from NY here. I work in a university hospital and have been working on epidemiological research. I am trying to find a statistician well...

    Started by gastrodoc‎, 10-25-2015 11:42 PM
    • Replies: 0
    • Views: 402
    10-25-2015, 11:42 PM Go to last post
  60. imultivariate analysis?

    Hi, I have some data looking at a few variables and whether they are different for patients receiving/not receiving certain treatment. They are a...

    Started by klara.m‎, 10-24-2015 09:13 AM
    • Replies: 3
    • Views: 400
    10-24-2015, 04:09 PM Go to last post

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