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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. calculation of relative risk.

    ..........................Smokers...................Non- Smokers Iron Exopsure.......+..........-...................+..........- Lung...

    Started by Bahaa123‎, Yesterday 03:13 PM
    • Replies: 0
    • Views: 73
    Yesterday, 03:13 PM Go to last post
  2. Which stat test to use

    Hi all, I have a data set like this: Nematodes copepods Pylochaetes Controle1 1 ...

    Started by mr.twino‎, 05-15-2013 03:18 AM
    • Replies: 1
    • Views: 65
    05-17-2013, 05:55 AM Go to last post
  3. test to assess proportional difference over time between groups

    I am trying to determine the appropriate test to run for a community-based intervention. There are 2 groups (intervention and control) and 2 time...

    Started by ncresearch‎, 05-16-2013 05:02 PM
    • Replies: 1
    • Views: 174
    05-16-2013, 08:20 PM Go to last post
  4. Correct assessment of the sampling distribution of the mean for my experiment?

    Hi, all. I'm trying to properly analyze data from an experiment and could use some help bridging the mental gap between statistical theory (which I...

    Started by lnhstats‎, 05-14-2013 02:24 PM
    • Replies: 7
    • Views: 242
    05-15-2013, 06:21 PM Go to last post
  5. Enrichment analysis between two sets of proteins

    I'm trying to calculate a statistical measure describing the overlap of two sets of proteins. The issue is that the sets are from different organisms...

    Started by aarstar‎, 05-14-2013 11:32 PM
    • Replies: 5
    • Views: 152
    05-15-2013, 02:09 PM Go to last post
  6. Surgical Outcomes?

    Does anyone know a good SSPS tutorial for the project I'm doing? I want to do a retrospective study to see if Drug A reduced postoperative...

    Started by mdi455‎, 05-14-2013 05:56 PM
    • Replies: 2
    • Views: 96
    05-15-2013, 10:07 AM Go to last post
  7. How to estimate a population prevalence from several primary studies

    I have received point estimates from several studies for the prevalence of a rare disease, and I would like to estimate the over-all prevalence in...

    Started by AVoelp‎, 05-15-2013 02:30 AM
    confidence interval, prevalence
    • Replies: 0
    • Views: 55
    05-15-2013, 02:30 AM Go to last post
  8. Site, treatment,numbers before and after

    Hi I have data from an environmental experiment. We treated a section of river bed to remove an invasive species. I could do with some help...

    Started by rorys‎, 05-14-2013 09:46 AM
    • Replies: 3
    • Views: 137
    05-14-2013, 11:57 AM Go to last post
  9. Using a repeated measures, two-way ANOVA.

    I want to compare the outcome of two different algorithms applied to one set of MRI images. Each MRI image will be manipulated twice. Once using the...

    Started by Araav‎, 05-12-2013 03:58 PM
    repeated measures, tukey, two-way anova
    • Replies: 0
    • Views: 177
    05-12-2013, 03:58 PM Go to last post
  10. Distribution of a subset of the complete sample

    Dear all, My question can be easily misunderstood, so please allow me to briefly explain the experimental conditions. I have measured a...

    Started by ampws‎, 05-11-2013 04:54 AM
    data distribution, non-parametric test, parametric test, sample size
    • Replies: 0
    • Views: 117
    05-11-2013, 04:54 AM Go to last post
  11. Anova? Chi-square?

    Hi, I've been asked to analyze some data and I wanted to get a second opinion on the way I plan to. I have a sample of 8000 teachers. For each...

    Started by jamesmartinn‎, 05-10-2013 11:37 AM
    • Replies: 3
    • Views: 261
    05-10-2013, 12:11 PM Go to last post
  12. How to build a regression model of survival data ?

    I would like to predict the response variable using different predictors. So far I have been working with multiple linear regression. However as my...

    Started by dada‎, 05-10-2013 06:11 AM
    • Replies: 0
    • Views: 126
    05-10-2013, 06:11 AM Go to last post
  13. Causal inference and survival analysis coursework

    Hey all, I'm an undergrad statistics student with an interest in causal inference topics such as propensity score analysis and instrument variable...

    Started by Birdnals‎, 05-04-2013 12:46 PM
    • Replies: 2
    • Views: 187
    05-09-2013, 04:05 PM Go to last post
  14. Correlation analysis

    Hi, First I have to apologise for the probably stupid question, but my statistic knowledge is pretty much 0 and after searching for an answer for...

    Started by Jeannine‎, 05-06-2013 07:32 PM
    • Replies: 2
    • Views: 184
    05-09-2013, 03:05 PM Go to last post
  15. Smile Correlation between lines:Odd man out

    Dear Friends, I am analyzing the presence of cis element in 1K upstream of some up regulated genes. I have got the number of elements in the...

    Started by Vinay‎, 05-08-2013 04:52 AM
    • Replies: 1
    • Views: 131
    05-08-2013, 09:28 PM Go to last post
  16. Survival analysis: how do i include a random effect and interval censoring?

    Hi, I'm trying to use some form of survival analysis (e.g. accelerated failure time or proportional hazards) to study seed germination time. My...

    Started by Tarek‎, 05-08-2013 01:43 PM
    frailty, grouped-time, interval censoring, sas, survival analysis
    • Replies: 0
    • Views: 98
    05-08-2013, 01:43 PM Go to last post
  17. Graphs, Funnel Plots, suggestions?

    Hi! I'm trying to display some data, let me describe it to you. I have a group of about 5000 teachers. For each teacher, I have the rate of...

    Started by jamesmartinn‎, 05-07-2013 11:12 AM
    • Replies: 4
    • Views: 165
    05-07-2013, 12:54 PM Go to last post
  18. Incidence & competing risks

    Hello, I'm a bit puzzled about competing risks. I've used competing risks methods (gray's test and fine and gray regression) a while ago, but...

    Started by anker‎, 05-06-2013 05:41 AM
    • Replies: 0
    • Views: 120
    05-06-2013, 05:41 AM Go to last post
  19. how to test 2x2 table with an one empty cell in admission patients?

    I am a clinician working for a community based hospital. A few days ago, my fellow doctor asked me if I could give some advice for her data. ...

    Started by navyblue00‎, 05-02-2013 08:20 PM
    • Replies: 1
    • Views: 180
    05-05-2013, 06:55 AM Go to last post
  20. How to normalize LC-MS data with minimum bias (proteomics)

    Hello all, I'm working with quantification of some modified peptides enriched from serum of sick and healthy people. In the crude data (integrated...

    Started by hkontro‎, 04-24-2013 12:40 PM
    normalization, proteomics, quantification
    • Replies: 8
    • Views: 313
    05-03-2013, 04:32 AM Go to last post
  21. Mean Residual Life

    Hi, I've been tasked with solving the mean residual life given the density function f(x) and the survival function S(x) I think mean residual...

    Started by chinarider25‎, 05-01-2013 02:00 PM
    mean residual life, mrl, stat, survival
    • Replies: 0
    • Views: 99
    05-01-2013, 02:00 PM Go to last post
  22. Survey

    I'm a Biostatistician working for a researcher who wants to find out if length of training would affect peoples opinion in choosing a certain medical...

    Started by ccasboy30‎, 05-01-2013 11:38 AM
    • Replies: 2
    • Views: 172
    05-01-2013, 12:38 PM Go to last post
  23. Very large samples

    Hello all, I am about to receive a very large sample, of around 10 million observations. I will explain. I am requested to statistically analyze...

    Started by NN_STAT‎, 05-01-2013 07:02 AM
    • Replies: 5
    • Views: 215
    05-01-2013, 09:14 AM Go to last post
  24. Dunnett's test for longitudinal data

    Dear Stats Folk, I have a one Control group and one patient group. I have measurements on Controls at one time point, while I have a single...

    Started by Jim Corbett‎, 04-30-2013 05:22 PM
    dunnett's, t-test
    • Replies: 0
    • Views: 214
    04-30-2013, 05:22 PM Go to last post
  25. pairwise comparison regardless effect

    Hi there, I want to do a pairwise comparison of gene expressions (continuous values) before and after treatment of a group of patients regardless...

    Started by bambam‎, 04-29-2013 04:23 AM
    • Replies: 2
    • Views: 143
    04-30-2013, 04:25 AM Go to last post
  26. Help needed for the interpretation of ANOSIM results in Primer

    As new to biostatistics I would appreciate some help on the interpretation of ANOSIM results in Primer. Thank you!!...

    Started by Koula‎, 04-29-2013 09:02 AM
    • Replies: 0
    • Views: 210
    04-29-2013, 09:02 AM Go to last post
  27. Time*predictor interaction term for longitudinal study analysis

    Hello Forum, Currently I am analyzing results of longitudinal study evaluating the effects of possible dichotomous predictor on continious outcome...

    Started by DSSS‎, 04-28-2013 10:07 PM
    • Replies: 0
    • Views: 135
    04-28-2013, 10:07 PM Go to last post
  28. Compare the variations of bacterial species between test groups

    Hello, I have been scratchiong my head for a few days on this problem, which should be pretty simple. I really hope someone can point me in the...

    Started by Koblenz‎, 04-28-2013 10:46 AM
    • Replies: 0
    • Views: 156
    04-28-2013, 10:46 AM Go to last post
  29. Odds ratios less than 1, how to make interpretation ?

    Hello all, How do I make interpretation of odds ratio equal to 0.02, given from a logistic model with a binary outcome and let's say 2 treatments...

    Started by NN_STAT‎, 04-27-2013 07:51 AM
    • Replies: 5
    • Views: 262
    04-28-2013, 12:33 AM Go to last post
  30. Wide CI for odds ratio

    Hello all, I ran a model that yields odds ratio, like the logistic regression does. I have received a very wide CI. To illustrate the reason,...

    Started by NN_STAT‎, 04-24-2013 08:12 AM
    • Replies: 5
    • Views: 192
    04-27-2013, 11:50 PM Go to last post
  31. Question More than 2 outcome (categorical), what is the statistical test?

    Hello everyone! If I have an outcome (dependent variable) is 3 outcomes (Scale of measurement: categorical/nominal) and the interdependent...

    Started by Halah‎, 04-26-2013 11:58 AM
    • Replies: 4
    • Views: 199
    04-26-2013, 12:32 PM Go to last post
  32. Kaplan-Meier and log-rank analysis

    Question about Kaplan-Meier analysis and log rank. I am currently working on a project using the National Cancer Institute's SEER database. A lot of...

    Started by savant624‎, 04-24-2013 06:03 PM
    • Replies: 0
    • Views: 160
    04-24-2013, 06:03 PM Go to last post
  33. A T test question

    This is a question on presenting the result of the effectiveness of weight loss program. There is only one group of subject and two time point ( pre...

    Started by kolokicy‎, 04-22-2013 09:45 PM
    • Replies: 4
    • Views: 322
    04-23-2013, 04:45 PM Go to last post
  34. Lightbulb Design Issue: Retrospective Cohort or Case Control?

    Good Morning! I am currently trying to decide which approach to my research question is best. I am using a large data set from a state agency. The...

    Started by christinarn2000‎, 04-11-2013 11:54 AM
    • Replies: 5
    • Views: 263
    04-22-2013, 09:18 PM Go to last post
  35. Testing the assumption of linearity in a multi-level logistic regression analysis

    Hello all! I am working on a multi-level logistic regression (Binary Outcome) model and am trying to finding the best way to check the assumption of...

    Started by Klh449‎, 04-19-2013 08:17 PM
    • Replies: 4
    • Views: 257
    04-22-2013, 01:24 PM Go to last post
  36. too high CV

    Hello friends, when i am analysing my data using ANOVA, i came up with a very large cv(55) is there any means to lower it? my design is 4x5 CRD with...

    Started by jamesbiot01‎, 04-14-2013 03:07 AM
    • Replies: 3
    • Views: 194
    04-20-2013, 08:37 AM Go to last post
  37. Test if non-negative measurements are significantly different from 0 (5 replicates)

    I have measurements basically indicating how much a gene is used in specific individuals. The way you do this is by counting how much gene product...

    Started by Rubber‎, 04-19-2013 04:41 PM
    • Replies: 1
    • Views: 235
    04-19-2013, 06:12 PM Go to last post
  38. Non-inferiority Cox model

    Hello, I am trying to design a study in which the primary endpoint is time to event. Due to some constraints, the study needs to be a...

    Started by NN_STAT‎, 04-17-2013 06:33 AM
    • Replies: 0
    • Views: 149
    04-17-2013, 06:33 AM Go to last post
  39. Variable prediction

    Hi everyone, I'm currently doing work with morphometry, working with data I've collected and with an already existing database. At the moment I'm...

    Started by PeterAlex‎, 04-05-2013 06:54 AM
    • Replies: 1
    • Views: 204
    04-17-2013, 05:21 AM Go to last post
  40. How to Report Dunnett MCT?

    Hello, How do I properly report an ANOVA followed by Dunnett's MCT in APA format? Below is the report minitab generates for Effects of Dose on...

    Started by sudds779‎, 04-16-2013 09:59 AM
    • Replies: 0
    • Views: 178
    04-16-2013, 09:59 AM Go to last post
  41. Question frequency of heterozygous allele between two groups

    I am sorry I am not statistician but I have a very simple (maybe stupid:)) question. I have case group of 4460 and controls of 5085, P value is...

    Started by manu26‎, 04-12-2013 04:47 AM
    allele, case control, frequecny
    • Replies: 0
    • Views: 118
    04-12-2013, 04:47 AM Go to last post
  42. control of type I error?

    Hello forum, I am seeking your advise. Here is the problem: In a clinical trial, we will collect MRI imaging data from each patient...

    Started by teddyofphilly‎, 04-11-2013 01:52 PM
    • Replies: 3
    • Views: 146
    04-11-2013, 02:24 PM Go to last post
  43. Correct statistical test to compare pre and post questions (dummy variable)

    Hi friends, What is the correct statistical test to compare a group who was tested in two points in time (pre and post) The same people. I have...

    Started by Marvin85‎, 04-11-2013 08:41 AM
    dummy variable ttest, statistical test, ttest
    • Replies: 2
    • Views: 166
    04-11-2013, 08:55 AM Go to last post
  44. Exclamation [SPSS - Binary logistic test - Interaction (moderator) ]

    DV: dichotomous (0 = show, 1 = no-show) IV (covariates): Geslacht = Gender dvd_week = Day of the week Gender (0 = females, 1 = males)...

    Started by Kelvin86‎, 04-10-2013 04:06 PM
    • Replies: 3
    • Views: 265
    04-10-2013, 06:15 PM Go to last post
  45. Wink Simple question concerning a population with known distribution and a smaller sample

    Hello, I have a complete population consisting of 6587 individuals (genes) and for each individual I have a distance value. These distance...

    Started by devking‎, 04-10-2013 01:59 PM
    • Replies: 0
    • Views: 220
    04-10-2013, 01:59 PM Go to last post
  46. Comparing Qualitative Integer Scores: Non-parametric alternative to ANOVA needed?

    I am trying to analyze data from the longitudinal qualitative scoring of knee joints to measure differences in disease severity by a number of...

    Started by dinsdale‎, 04-10-2013 10:09 AM
    • Replies: 0
    • Views: 159
    04-10-2013, 10:09 AM Go to last post
  47. Mann-Whitney U and Bonferroni Correction

    I recently presented some work in my department in which my colleagues and I had applied a Mann-Whitney U test for multiple pairwise comparisons. We...

    Started by Zachariah‎, 04-05-2013 01:27 PM
    bonferroni correction, mann-whitney u, non-parametric
    • Replies: 3
    • Views: 403
    04-08-2013, 09:31 AM Go to last post
  48. Removing interaction effect on 2-way ANOVA?

    Hello, I've run a 2 way ANOVA of my research results and got these 3 p-values: A=0.001, B=0.069, and A*B=0.167. My professor now wants me to remove...

    Started by Lizzbee‎, 04-07-2013 08:44 PM
    anova, data, interaction, p-value, sigmaplot
    • Replies: 1
    • Views: 209
    04-07-2013, 09:02 PM Go to last post
  49. multivariate Cox regression, ordinal variable as dummy variables, and p value

    I'm trying to understand a paper on kidney cancer research. The study uses a multivariate Cox regression. The outcome variable is death/no death from...

    Started by KidneyBoy‎, 04-05-2013 02:27 PM
    • Replies: 0
    • Views: 210
    04-05-2013, 02:27 PM Go to last post
  50. How do I show something is an 'independent variable'?

    Please help. I am totally confused about how to show that something is an independent risk factor. I.e. in a cohort study: Group A (n=1000) -...

    Started by RoseMarie‎, 04-02-2013 04:19 PM
    independent risk factor, risk ratio
    • Replies: 2
    • Views: 236
    04-03-2013, 01:04 AM Go to last post
  51. Goodness-of-link test

    Hello, I am trying to test whether my choice of link function is correct using the goodness-of-link test. So, firstly since I am testing the...

    Started by GTaiko‎, 04-02-2013 10:31 PM
    • Replies: 0
    • Views: 221
    04-02-2013, 10:31 PM Go to last post
  52. probably any easy question for the stat inclined (not me)

    Hi all, A population of patients were tested for 3 viruses and have a variety of symptom questions associated. For example: ...

    Started by bdiddy‎, 04-01-2013 06:28 PM
    • Replies: 1
    • Views: 235
    04-02-2013, 07:10 AM Go to last post
  53. Smile Sampling Size determination

    Hello All I have a population of 22000 individuals. I wanted to mesure a mean value of a specific parameter. for this purpose I randomly tested...

    Started by sirszimansky‎, 03-31-2013 02:05 AM
    • Replies: 0
    • Views: 245
    03-31-2013, 02:05 AM Go to last post
  54. Working out risk factors for a medical complication?

    Hi All - HELP! I have a large dataset on women in labour, and I'm interested in finding out risk factors for a particular complication of labour....

    Started by obsreg‎, 03-24-2013 04:11 PM
    disease, logistic regression, odds ratio, relative risk
    • Replies: 2
    • Views: 226
    03-29-2013, 08:19 AM Go to last post
  55. How to present data after Holm-Bonferroni Correction

    Hi all, I am manually using Holm-Bonferroni method to correct my data as I can't find a way to do it using software. As the data is relatively...

    Started by artery‎, 03-19-2013 05:48 AM
    bonferroni, holm
    • Replies: 1
    • Views: 291
    03-28-2013, 08:20 PM Go to last post
  56. Testing significance of frequencies by position of nucleotide pairs

    Hi all, I have a set of frequencies for each of the 16 possible nucleotide pairs at a given position in a sequence. I want to test whether any of...

    Started by xaio21‎, 03-28-2013 06:53 PM
    spss
    • Replies: 0
    • Views: 242
    03-28-2013, 06:53 PM Go to last post
  57. Sample size with G power

    Hello I ran some sample size calculations using Gpower, in order to find the minimum required sample size for the Fisher exact test, since I need...

    Started by NN_STAT‎, 03-22-2013 09:21 AM
    • Replies: 2
    • Views: 278
    03-27-2013, 09:37 PM Go to last post
  58. one way ANOVA for rank data?

    I was recently reading up on nonparametric alternatives to one way ANOVA and came across a description of ANOVA on rank data...

    Started by Disvengeance‎, 03-27-2013 03:02 PM
    • Replies: 0
    • Views: 216
    03-27-2013, 03:02 PM Go to last post
  59. Comparing 2 different pop sizes

    Hi, I am running up against some problems in my stats analysis. Please can anyone give me a hand on this... I have data on Emergency Department...

    Started by PedroR‎, 03-27-2013 06:54 AM
    • Replies: 0
    • Views: 208
    03-27-2013, 06:54 AM Go to last post
  60. Hypothesis testing for very large sample sizes

    Hello everyone, I am trying to figure out which hypothesis test is best for my research. I have two groups of patients (Group 1, n = 726,314...

    Started by Bboggess‎, 03-26-2013 03:01 PM
    • Replies: 1
    • Views: 245
    03-26-2013, 03:30 PM Go to last post

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