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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. non-parametric data for reference ranges

    Hello, I am very new to statistical analysis, but am very excited to to be learning it. I am working on finding reference ranges for some...

    Started by schmidlk‎, 07-28-2014 08:36 PM
    blood tests, medical statistics, new in the field, non-parametric, reference range
    • Replies: 0
    • Views: 3,317
    07-28-2014, 08:36 PM Go to last post
  2. Question How to interpret residual plot of a logistic regression?

    Hi all, I'm working on a default probability model and was modeling the default probability using logistic regression. The pearson residual and...

    Started by sufeipopo‎, 07-28-2014 02:55 PM
    • Replies: 1
    • Views: 5,628
    07-28-2014, 03:12 PM Go to last post
  3. Arrow Chi square: Goodness of fit and test of independence

    Ok, so Chi square GOF tests a variable for its fit to a theoretical proportion. Yet, a Chi test of independence does this, for two variables, with...

    Started by TheSloth‎, 07-27-2014 05:19 AM
    • Replies: 0
    • Views: 2,407
    07-27-2014, 05:19 AM Go to last post
  4. Statistical method to rule out cross-contamination?

    Hello, I hope there is someone who can help me find the right method for my needs. I have conducted a study in which I captured bees at several...

    Started by Bcentralis‎, 07-25-2014 03:32 PM
    • Replies: 0
    • Views: 1,523
    07-25-2014, 03:32 PM Go to last post
  5. 3D printing project + small sample size (5). How to analyze questionnaire data?

    Hi there, I am currently working on a research project investigating the use of 3D printed patient specific anatomy in pre-operative planning. The...

    Started by stanleyliew‎, 07-24-2014 04:54 PM
    • Replies: 0
    • Views: 1,405
    07-24-2014, 04:54 PM Go to last post
  6. including items in final version of new instrument

    I have 2 questions I would like advice on. They relate to a paper I'm reviewing for a journal. When developing a new instrument, if you do a...

    Started by MarcelProust‎, 07-22-2014 12:10 PM
    • Replies: 0
    • Views: 1,563
    07-22-2014, 12:10 PM Go to last post
  7. fish and seagrass help

    Hello, I'm doing something very similar with seagrass and bare sand substrates fish data and just wondering if you had any luck figuring out how to...

    Started by helbob‎, 07-18-2014 07:59 AM
    • Replies: 5
    • Views: 1,724
    07-21-2014, 06:04 AM Go to last post
  8. [SPSS] Comparison of Fish abundances over 3 inter-tidal zones and 4 sites.

    Hi there, I'm relatively new to statistical analysis so bare with me... I have a research project that aims to find whether fish species...

    Started by Shaan‎, 04-24-2014 08:32 AM
    • Replies: 2
    • Views: 2,149
    07-20-2014, 04:30 AM Go to last post
  9. Combining two ORs with the same control group

    Hi everybody. I am doing a meta-analysis of observational studies. As the disease I am working on has different stages, some of the studies reported...

    Started by amirh899‎, 07-16-2014 09:21 AM
    • Replies: 12
    • Views: 2,377
    07-17-2014, 01:19 PM Go to last post
  10. Correct Order in Repeated-Measures Design

    A group of 8 volunteers performed a task on two different devices and a particular variable was measured. The question to be answered is if there is...

    Started by DaDeKi‎, 07-13-2014 04:26 PM
    • Replies: 5
    • Views: 1,478
    07-17-2014, 09:48 AM Go to last post
  11. Randomized controlled trial sample size calculation

    Sorry if this is in the wrong thread. I am trying to determine if a research project is feasible to conduct by calculating the sample size needed. ...

    Started by efficientfuel‎, 07-16-2014 02:24 PM
    • Replies: 2
    • Views: 1,717
    07-16-2014, 04:29 PM Go to last post
  12. When do sample size calculations need to adjust for clustering?

    I am aware that sample size calculations for cluster RCTs must adjust for clustered data. I would like to understand better if such adjustment might...

    Started by mayiara‎, 07-14-2014 04:53 PM
    clustering, power, sample size calculation
    • Replies: 1
    • Views: 1,938
    07-15-2014, 01:53 AM Go to last post
  13. Relationship Satisfaction short Study participants wanted -

    You must be in a relationship to participate in these studies. You can be anywhere on the planet. This preliminary study should only take anyone a...

    Started by williamsven‎, 07-14-2014 10:44 AM
    • Replies: 0
    • Views: 1,420
    07-14-2014, 10:44 AM Go to last post
  14. which statistic test should I use

    Hello, I have a problem in picking the right statistic test in my case. I have analyzed the microbial community in one sample with different methods,...

    Started by rigel‎, 07-13-2014 12:26 AM
    • Replies: 0
    • Views: 1,014
    07-13-2014, 12:26 AM Go to last post
  15. Repeated measures analysis

    I have a data set of 450 subject with each having 3 repeated measurements using a new device. I want to compare these measurements with the gold...

    Started by Bardiya‎, 07-11-2014 08:33 PM
    • Replies: 0
    • Views: 1,286
    07-11-2014, 08:33 PM Go to last post
  16. malthusian growth statistics

    I've got populations consisting of a mix of two strains. I have the numbers of each strain at t=0hrs and t=24hrs. I have been trying to calculate...

    Started by pstils‎, 07-11-2014 11:33 AM
    evolution, growth, malthusian, selection
    • Replies: 0
    • Views: 1,571
    07-11-2014, 11:33 AM Go to last post
  17. Directional Statistics

    Is anyone familiar with directional statistics? Circular or spherical? I have a some data that I've never considered before - the distribution of...

    Started by evoeco‎, 07-10-2014 02:01 PM
    • Replies: 0
    • Views: 2,428
    07-10-2014, 02:01 PM Go to last post
  18. Experimental design and mixed models

    Hello, I want to test effect of PH on larval development. I would like to know what is the best experimental design and statistical analysis. ...

    Started by statah‎, 07-09-2014 06:07 PM
    • Replies: 0
    • Views: 1,311
    07-09-2014, 06:07 PM Go to last post
  19. 2-way ANOVA or not 2-way ANOVA?

    Hi, I'm currently doing an experiment assessing the effect that 4 different growth mediums have in 3 different O2 concentrations. There are 6...

    Started by Kudu97‎, 07-08-2014 07:09 AM
    • Replies: 1
    • Views: 1,322
    07-08-2014, 08:51 AM Go to last post
  20. Linear Mixed Effects and interpreting transformations

    Hi, I'm running a hierarchical linear mixed effects model in R (subject is nested in dyad). My dependent variable is a continuous variable. When I...

    Started by jposluns‎, 07-05-2014 03:03 PM
    box-cox, homogeneity, mixed effects model, transformations
    • Replies: 0
    • Views: 1,174
    07-05-2014, 03:03 PM Go to last post
  21. Nested design

    I am conducting a study investigating the effects of different media treatments on protein expression in cells. I have four levels of media treatment...

    Started by leonsmyth‎, 07-03-2014 06:29 PM
    • Replies: 1
    • Views: 2,074
    07-04-2014, 06:25 AM Go to last post
  22. Can I use Cox regression in a nested case-control study to get adjusted risk ratios?

    I have 70 patients who died suddenly and I've drawn 140 controls for these patients (2:1 matching on age, gender, coronary artery disease and...

    Started by tkentta‎, 06-17-2014 09:57 AM
    • Replies: 1
    • Views: 2,528
    06-29-2014, 10:43 AM Go to last post
  23. 2-way Anova design repeated across an extra factor. Which approach is the best?

    Hello to everybody, I am a student working on a trial experiment to find the best combination of growing media, fertilizer application and...

    Started by Augustas‎, 06-28-2014 10:52 AM
    • Replies: 0
    • Views: 1,462
    06-28-2014, 10:52 AM Go to last post
  24. Comparing sex ratio's in 3 different areas and comparing to 50/50 sex ratio

    I'm having a little trouble with some the stats for a project i'm doing. I haven't taken it in years. I need to compare the sex ratios in 3 areas...

    Started by Biology‎, 05-22-2014 09:39 PM
    pearson chi square test
    • Replies: 5
    • Views: 2,922
    06-27-2014, 04:24 PM Go to last post
  25. interpreting multi-level logit model

    Hi, I posted this in the psychologiy statistics forum as well, but haven't gotten a response. I thought maybe it would fit better here. I have...

    Started by winnie1825‎, 06-26-2014 01:46 PM
    logistic multilevel, multi level, multilevel model, stata output
    • Replies: 0
    • Views: 1,504
    06-26-2014, 01:46 PM Go to last post
  26. Probability distribution of all possible combinations

    Hi to everybody! I would ask an advice on an analysis that I want to do. I have n=69 balls, within 69, 17 are black balls, 29 white balls, 22...

    Started by xgabrix‎, 06-23-2014 11:58 AM
    combinations, probability distribution
    • Replies: 0
    • Views: 1,135
    06-23-2014, 11:58 AM Go to last post
  27. Using Repeated Measures ANOVA

    We have just finished an experiment, where we had samples distributed into 6 groups and each group receiving a different treatment. Each group had 5...

    Started by theblackalchemist‎, 06-22-2014 11:10 AM
    • Replies: 0
    • Views: 1,193
    06-22-2014, 11:10 AM Go to last post
  28. Application in Medicine: Name Entity Recognition and Relation Extraction

    I am trying to do Name Entity Recognition and relation extraction on clinical text notes. Since this domain is specific, I have couple of questions:...

    Started by Xin 61‎, 06-21-2014 04:15 PM
    medicine, ner, relation extraction
    • Replies: 0
    • Views: 1,423
    06-21-2014, 04:15 PM Go to last post
  29. Survival Analysis: Unequal Follow-up Time

    Hi! I wanted to get some feed back for a study idea that's in the works. I haven't done much applied work in survival analysis, so hopefully you...

    Started by jamesmartinn‎, 06-09-2014 01:55 PM
    • Replies: 4
    • Views: 3,575
    06-18-2014, 07:40 PM Go to last post
  30. Reconciling differences seen in survival (log-rank vs logistic regression)

    Doing survival analysis on an intervention that has been shown to significantly improve overall survival (OS) in previous studies (time and again). ...

    Started by noviceguest‎, 06-10-2014 11:07 AM
    • Replies: 1
    • Views: 1,502
    06-18-2014, 05:05 PM Go to last post

    Dear all, I have been looking everywhere for answers (forums, books, websites etc.) but I am still struggling with a few statistical questions. I...

    Started by GQU‎, 06-18-2014 12:42 AM
    gamm model, permanova
    • Replies: 0
    • Views: 1,336
    06-18-2014, 12:42 AM Go to last post
  32. two-way ANOVA on actual glucose data

    Hi! I have some trouble with the interpretation of the post hoc results. For my thesis i have to comapare the effect of a new antidiabetic drug...

    Started by ivn‎, 06-15-2014 08:31 PM
    • Replies: 3
    • Views: 3,825
    06-16-2014, 11:27 AM Go to last post
  33. Post Non Inferiority Trial

    Hi there, I have a trial in which one group is receiving a drug and the other group is getting placebo. We want to try and show that the placebo...

    Started by msklokov‎, 06-09-2014 03:46 PM
    • Replies: 2
    • Views: 1,722
    06-09-2014, 10:04 PM Go to last post
  34. Fst overall and pairwise Fst among population AMOVA

    Dear Biostatistician, I have done an AMOVA analysis on mtDNA sequences, partitioned on 14 populations (with a variable number of individuals in...

    Started by xgabrix‎, 06-08-2014 07:15 AM
    amova, fst
    • Replies: 0
    • Views: 2,071
    06-08-2014, 07:15 AM Go to last post
  35. Need critic and help on survival model

    Hey all, I am in need of some help or critic regarding my model for a research paper and i've lost my confidence about the regression by now... ...

    Started by Nowak‎, 06-04-2014 09:23 AM
    • Replies: 3
    • Views: 2,394
    06-06-2014, 12:16 PM Go to last post
  36. Comparing p-values from multiple permutation (Mantel) tests on variations of the same

    I am comparing the relationship between genetic and geographic distance of individuals in a wild animal population. The hypothesis is that...

    Started by newbieguest‎, 06-02-2014 10:35 AM
    mantel test, null distribution, p-values, permutations
    • Replies: 0
    • Views: 1,182
    06-02-2014, 10:35 AM Go to last post
  37. repeated measures factorial ANOVA post hoc test

    Currently I am working on a way to distinguish Delirious patients from patients who still suffer from anesthesia and controls. I use the EEG and...

    Started by Miek08‎, 06-02-2014 10:22 AM
    factorial anova, post hoc, repeated measures
    • Replies: 0
    • Views: 1,704
    06-02-2014, 10:22 AM Go to last post
  38. Fit statistics of the baseline function

    I need to show a fit of the baseline survival function of a weibull and a cox regression But i have no idea how to do this and which statistic to...

    Started by studentbelg‎, 06-02-2014 09:53 AM
    • Replies: 0
    • Views: 1,436
    06-02-2014, 09:53 AM Go to last post
  39. Pre and Postop Questionnaire

    I have around 10 sets of people who have completed a questionnaire before and after intervention For 29 or so people I they have only returned...

    Started by omnitude‎, 05-31-2014 01:26 PM
    • Replies: 0
    • Views: 1,248
    05-31-2014, 01:26 PM Go to last post
  40. accelerated time model with proportional hazards

    $coef Estimate SE lambda 0.004424690 0.005026449 gamma 0.888627728 0.108972639 treatment -0.646997631...

    Started by studentbelg‎, 05-29-2014 08:02 AM
    • Replies: 1
    • Views: 1,364
    05-29-2014, 07:11 PM Go to last post
  41. Funnel Plot - not based on rate, %, expected v actual count.

    Hi, I have been tasked with producing some funnel plots that are somewhat different to the ones i am used to producing. Normally i would be...

    Started by robsmith1306‎, 05-28-2014 08:49 AM
    confidence interval, excel, funnel plot, health research, standard error
    • Replies: 0
    • Views: 1,869
    05-28-2014, 08:49 AM Go to last post
  42. Kolmogorov–Smirnov test - perturbation values

    I am comparing two distributions using the two sample Kolmogorov-Smirnov test. I've read one paper where the authors argue that before you can...

    Started by helpwithstats‎, 05-27-2014 07:59 AM
    • Replies: 4
    • Views: 7,318
    05-27-2014, 02:20 PM Go to last post
  43. Complication Rate comparison

    I'm trying to compared the rate of a complication occurring in two different types of treatment. I have full set of demographic data for the...

    Started by omnitude‎, 05-20-2014 11:13 AM
    • Replies: 2
    • Views: 1,817
    05-20-2014, 04:51 PM Go to last post
  44. Help with variable selection in logistic regression using a small dataset

    Hello. I have a relatively small data-set looking at a binary outcome of death after a medical procedure. There are 102 patients total in the...

    Started by stat2014‎, 05-17-2014 08:31 PM
    logistic regression, small data set, variable selection
    • Replies: 1
    • Views: 1,741
    05-18-2014, 05:40 AM Go to last post
  45. Need help with paired t-test?

    Hello forum, It has been years since I took stats in college and I am having difficulty determining which test is most appropriate. Here is...

    Started by Jason C.‎, 05-13-2014 01:35 PM
    • Replies: 1
    • Views: 1,567
    05-13-2014, 04:04 PM Go to last post
  46. Smile Sample size needed for a observational correlation study?

    hi I'm pretty helpless in this. Any kind soul willing to guide me on this. I'm writing up a proposal on a correlation study. The dependent...

    Started by warhunter‎, 05-09-2014 02:48 AM
    • Replies: 2
    • Views: 1,919
    05-13-2014, 03:32 PM Go to last post
  47. Meta-Analysis- GEO datasets

    Im using data from GEO and the GEO2R online analysis tool provided by NCBI. The GEO2R analysis give adjusted P, P, t scores. I have 5-10 studies...

    Started by smectutor‎, 05-11-2014 11:01 AM
    • Replies: 0
    • Views: 1,672
    05-11-2014, 11:01 AM Go to last post
  48. Wich margin of non-inferiority to pick?

    Hi everyone, I have been thinking about this quite long: Event rate of death in particular sick population is 22% Treatment A has a...

    Started by klapacius‎, 04-30-2014 04:45 PM
    clinical trials, non-inferiority
    • Replies: 1
    • Views: 1,643
    05-07-2014, 05:38 PM Go to last post
  49. Logistic regression, sample sizes and bootstraping

    Hello, this is my first post. I currently I'm working in my phD in a multivariate logistic model but I have a problem regarding the sample size of my...

    Started by Edu‎, 05-06-2014 06:31 PM
    bootstrap, logisitic regression, r language, sample size
    • Replies: 2
    • Views: 1,670
    05-07-2014, 08:00 AM Go to last post
  50. Matching Case-control study. Help Needed!

    Hi, I'm studying medical data. My case have Preterm Premature Rupture of Membranes and benefit of amniocentesis for detection of infection. My...

    Started by aesc‎, 05-04-2014 06:07 AM
    • Replies: 0
    • Views: 1,458
    05-04-2014, 06:07 AM Go to last post
  51. Help with missing data

    I am trying so hard to understand this. I am not wanting any answers....I want to learn this on my own. I am attaching an excel sheet. Can somebody...

    Started by Susan1219‎, 04-25-2014 01:53 AM
    • Replies: 1
    • Views: 1,423
    05-02-2014, 10:36 AM Go to last post
  52. Comparing survival against standard population

    Hello. I have the survival data (survival time + time of death) of a population after a certain treatment, as well as a standard population built...

    Started by levolac‎, 04-23-2014 04:38 AM
    survival analysis
    • Replies: 2
    • Views: 1,622
    05-01-2014, 07:25 AM Go to last post
  53. Good model for association of for prediction?

    Hello everybody, I have a "conceptual issue": I have been told that the program that performs best in finding a lot of feature associated to a...

    Started by scratchscratch‎, 04-29-2014 11:24 AM
    association, association study, prediction
    • Replies: 1
    • Views: 1,986
    04-29-2014, 01:47 PM Go to last post
  54. When to use Multivariable vs. Multivariate?

    Hi - I recently met with a statistician to discuss some of my data, and learned quite a bit, but was still left with some questions. I have...

    Started by jms88‎, 04-28-2014 03:51 PM
    generalized linear model, multivariable, multivariate, multivariate analysis, regression
    • Replies: 0
    • Views: 3,845
    04-28-2014, 03:51 PM Go to last post
  55. Inserting Controls in a logistic regression

    A beginner here, so bear with me :) I have 3 groups of patients and 1 control group. There are many independent variables to be tested. However, a...

    Started by Logician‎, 04-27-2014 06:56 PM
    • Replies: 1
    • Views: 2,099
    04-27-2014, 08:36 PM Go to last post
  56. Please help with weighted # of cases in binary logistic reg

    Hello everybody, I have a question about the total number of cases used in the binary logistic regression analysis with weighted cases (SPSS) ...

    Started by kiton‎, 04-27-2014 03:58 PM
    • Replies: 0
    • Views: 1,231
    04-27-2014, 03:58 PM Go to last post
  57. Help for master degree

    Good evening, I need your help I was admitted to the master programme in biostatistics in the university of glasgow, I was also admitted to the same...

    Started by Akaros‎, 04-24-2014 07:23 PM
    • Replies: 1
    • Views: 2,225
    04-24-2014, 08:44 PM Go to last post
  58. Help choosing statistical test for conservation research

    So I am looking at ecoregions in South America (basically regions of a defined habitat type). I have two types of data for each ecoregion: 1....I...

    Started by Lousie22‎, 04-22-2014 08:00 AM
    • Replies: 1
    • Views: 1,280
    04-22-2014, 09:16 AM Go to last post
  59. Question Which kind of test is suitable for this type of question?

    Hi, I'm new to using R and a statistics newbie unfortunately. I was wondering if any of you could please tell which kind of test would be suitable...

    Started by Elsa‎, 04-12-2014 08:16 AM
    • Replies: 3
    • Views: 1,483
    04-21-2014, 04:47 PM Go to last post
  60. Appropriate hypothesis test for beta or fractional logistic distributions

    Hi! Thanks to previous suggestions I have determined that my bounded data sets are fit well by beta and/or fractional logistic distributions. I am...

    Started by phaynes‎, 04-16-2014 09:41 AM
    beta distribution, bounded data, hypothesis test
    • Replies: 1
    • Views: 2,101
    04-16-2014, 09:45 AM Go to last post

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