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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Not sure if ANCOVA or multivariable linear regression is best

    Iím using SAS to analyze data for a quality of life (QoL) project and Iím trying to answer two research questions. I want to present something simple...

    Started by Porter‎, 09-08-2013 04:30 AM
    • Replies: 0
    • Views: 1,354
    09-08-2013, 04:30 AM Go to last post
  2. Calculating NNT or NNH for continuous data represented as a numerical change in scale

    Could someone please tell me how i can go about calculating NNT (number needed to treat) or NNH (number needed to harm), with continuous data? I am a...

    Started by aquarian85‎, 09-07-2013 10:26 PM
    nnt nnh continuous data
    • Replies: 0
    • Views: 3,390
    09-07-2013, 10:26 PM Go to last post
  3. Binomial Probability best fit curve?

    I have a probability question for some research I am doing. I think I am dealing with a binomial distribution and I was wondering if there was a way...

    Started by MRIAV‎, 09-06-2013 09:30 AM
    • Replies: 3
    • Views: 1,980
    09-06-2013, 05:43 PM Go to last post
  4. best approach to test an associations betwean genes

    hi everyone, i am not familier with the world of biology and i was asked in one of my courses to analyze the relationships of 4 genes and wether or...

    Started by keren.assulin‎, 09-06-2013 11:26 AM
    • Replies: 0
    • Views: 1,264
    09-06-2013, 11:26 AM Go to last post
  5. Statistical Test for fold changes of gene expression

    Hi everyone, I am currently doing my masters and working on gene expression in tumor and control animals. I am really lost when it comes to the...

    Started by biba‎, 09-06-2013 01:15 AM
    • Replies: 4
    • Views: 4,870
    09-06-2013, 10:48 AM Go to last post
  6. Blocking on Binomial Data

    I remember from college statistics that blocking can be used, especially in agriculture. I would like to block but use binomial distributed data. Is...

    Started by kopomeroy‎, 09-06-2013 10:01 AM
    binomial analysis, blocking
    • Replies: 0
    • Views: 1,177
    09-06-2013, 10:01 AM Go to last post
  7. Comparing mean and median values

    Hi everyone, I'm working with Stata to compare the mean and median values of several continuous variables between 2 independent samples (sample...

    Started by simonja‎, 09-04-2013 01:15 PM
    • Replies: 4
    • Views: 2,514
    09-05-2013, 04:37 AM Go to last post
  8. Statitical Power calculation for clinical data :)

    I was calculating Statistical Power. I am not sure about the test in R. The data is as follows: Females 1224 Males 1438 OBSERVED...

    Started by satish1482‎, 09-03-2013 02:56 PM
    • Replies: 0
    • Views: 1,521
    09-03-2013, 02:56 PM Go to last post
  9. Red face Please help with haplotypes!!!

    Hi guys, I posted this question yesterday but sadly had no reply :( I really need help here :shakehead I am using HAPSTAT to run a haplotype X...

    Started by susy‎, 08-28-2013 04:27 AM
    haplotype genetics
    • Replies: 1
    • Views: 1,052
    09-03-2013, 02:46 PM Go to last post
  10. Simple question.

    What conclusion can i draw from this: I have the number of new cases of Parkinson's disease in a hospital and I have the distribution of cases with...

    Started by iCat‎, 09-03-2013 12:00 PM
    • Replies: 4
    • Views: 1,467
    09-03-2013, 01:33 PM Go to last post
  11. How do I combine multiple repetitions to canculate standard error?

    Hello! I am not sure that i am in the right forum, but i will give it a go anyhow: I have 3 different samples from the same treatment, i run each...

    Started by kshectma‎, 09-02-2013 02:50 AM
    • Replies: 0
    • Views: 1,046
    09-02-2013, 02:50 AM Go to last post
  12. Which test is appropriate for comparing sets of ratios?

    I am in a biology class in which we are comparing allometric vs isometric growth in humans. We have calculated several height to body part ratios...

    Started by derekvtx‎, 08-28-2013 05:33 PM
    • Replies: 3
    • Views: 1,683
    09-01-2013, 11:25 AM Go to last post
  13. Multiple Ailments

    1 in 24 people in the US are diagnosed with COPD, 1/314 with Parkinsons, 1 in 12 with heart disease. What is the chances for a person to have a 3...

    Started by Blueray123‎, 08-24-2013 12:01 PM
    • Replies: 5
    • Views: 10,609
    08-31-2013, 04:33 PM Go to last post
  14. Logistic Regression (very small proportion of 'yes')

    Hi Everyone, I am working on a logistic regression problem (injury predicted by air temperature and physical training program). Problem is that...

    Started by smh5154‎, 08-27-2013 12:40 PM
    • Replies: 13
    • Views: 2,549
    08-30-2013, 03:09 PM Go to last post
  15. Cool Statictical suggestion regarding DOE and GLM for the pharmacutical related problem

    We performed a DOE to study the relationship between simulated intestinal fluid (SIF) components and solubility of drugs. The DOE is composed of 7...

    Started by joybaker‎, 08-22-2013 05:33 AM
    • Replies: 3
    • Views: 1,755
    08-28-2013, 10:08 AM Go to last post
  16. 2^4 On-farm trial - only 4 plots per farm -> what design possibilities?

    Hello, I have to design an on-farm trial with possibly about 600 farmers involved (setting: Madagascar, so rather illiterate participants). ...

    Started by Suzany‎, 08-15-2013 05:19 AM
    multi-factor model, on farm trial
    • Replies: 1
    • Views: 1,398
    08-28-2013, 03:17 AM Go to last post
  17. Regression between two data sets of different time scales/collection dates

    Hi there. Thanks for looking at my post. I've been working on preprocessing/organizing a data set that I believe I would like to run a regression...

    Started by northtexas55693‎, 08-28-2013 12:01 AM
    • Replies: 0
    • Views: 1,451
    08-28-2013, 12:01 AM Go to last post
  18. Anybody work on Decision Engineering S/W?

    E.g., a woman goes in the hospital, they type her symptoms into a computer and it says she has a 5% chance of leaving the hospital alive. But. ....

    Started by Outlier‎, 08-27-2013 11:42 AM
    • Replies: 0
    • Views: 1,593
    08-27-2013, 11:42 AM Go to last post
  19. Calculating Smallest Detectable Difference when mean is around 1 and MSE < 1

    Apologies if this is in the wrong forum, and please move if this is the case (I have also posted this in the Statistical Research forum). Just a...

    Started by rodwhiteley‎, 08-26-2013 03:04 AM
    mdc, mse, sem
    • Replies: 0
    • Views: 1,244
    08-26-2013, 03:04 AM Go to last post
  20. Comparing Ordinal IV and Ordinal DV

    Hey guys another question So I have set up this experiment about the effects of Virtual Surgical Planning on various aspects of outcomes of the...

    Started by mjbarteau‎, 08-22-2013 03:55 PM
    • Replies: 6
    • Views: 1,560
    08-25-2013, 07:47 PM Go to last post
  21. How to compare 4 related, non-parametric, categorical means.

    Hi, A friend of mine did a study where she implanted 4 different types of surgical mesh into 10 rats. She then meassured adhesion formation index...

    Started by ibaley‎, 08-23-2013 01:10 PM
    • Replies: 1
    • Views: 1,653
    08-23-2013, 02:40 PM Go to last post
  22. [SPSS - ANOVA] Should I use a one-way ANOVA or one-way repeated measures ANOVA ?

    Hi all, I am currently trying to analyse data I obtained from my research but I am not sure if I have to use a one-way/two way ANOVA or a...

    Started by jessi6887‎, 08-23-2013 08:02 AM
    • Replies: 0
    • Views: 1,186
    08-23-2013, 08:02 AM Go to last post
  23. Multivariate meta-analysis

    Hi all, I'm a graduate student in Biology and I'm preparing a PhD application at the department of Ecotoxicology of my university. The title of my...

    Started by Detlef‎, 08-22-2013 02:14 AM
    • Replies: 1
    • Views: 1,449
    08-22-2013, 01:24 PM Go to last post
  24. Correlated Data Analysis

    2 down vote favorite I am working on yield of fisheries in three different pools. The yield output was measured in terms of their length gain...

    Started by bjslubana‎, 07-10-2013 01:12 AM
    correlation regression, model selection
    • Replies: 2
    • Views: 1,660
    08-21-2013, 10:51 AM Go to last post
  25. significance calculation

    Hi I am working wit a data set where protein expression is measured in 11 tissues in normal condition. Basically I have got a huge spreadsheet of...

    Started by DNA_is_k‎, 08-18-2013 10:33 AM
    • Replies: 0
    • Views: 1,974
    08-18-2013, 10:33 AM Go to last post
  26. Appropriate statistic for ratio of measurements?

    I am designing a study where I measure the electrical conductivity of tissue in two directions. My (pseudo) hypothesis is that, regardless of the...

    Started by montyhp‎, 08-18-2013 09:08 AM
    measurements, ratio
    • Replies: 0
    • Views: 1,044
    08-18-2013, 09:08 AM Go to last post
  27. Comparing 2 groups with unequal number of samples + comparing multiple groups

    Hello everyone, this is my first post here. I have been doing some surfing and reading on this forum and I must say, you guys are great. I am...

    Started by zaf‎, 08-16-2013 11:48 AM
    • Replies: 5
    • Views: 2,278
    08-17-2013, 02:35 PM Go to last post
  28. comparing two groups with binary data

    Hi, Suppose I am testing two drugs, I and II. The response profile is either I >II, II<I or I == I. I was trying to figure out the best way to do...

    Started by greeniguana‎, 08-15-2013 10:05 PM
    • Replies: 2
    • Views: 3,593
    08-16-2013, 07:43 AM Go to last post
  29. ROC curve analysis - Implications of unequal no. of observations in each group

    Hi, I'm using ROC curve analysis to identify thresholds for accelerometer (activity monitor) raw count data in order to classify count data as...

    Started by ryanj8‎, 08-14-2013 09:10 AM
    • Replies: 2
    • Views: 1,227
    08-15-2013, 03:54 AM Go to last post
  30. Inter & intra-subject reliability

    I would like to conduct a research to measure inter- & intra-subject reliability (less than 30 subjects) in preparing 3 types of fluids (A, B, C). ...

    Started by tbing‎, 08-14-2013 06:27 AM
    • Replies: 0
    • Views: 2,981
    08-14-2013, 06:27 AM Go to last post
  31. GLM Multivariate on Numerous Dependent Variables ~ Isolate Different Types of Tests?

    So here is a question that is bothering me, and I cannot seem to find the answer on google or site searches Let's say I have a database with two...

    Started by Panurge‎, 08-05-2013 04:04 PM
    • Replies: 3
    • Views: 1,689
    08-12-2013, 08:51 PM Go to last post
  32. Comparing the effect of 26 compounds on 2 different organisms

    Hello, I have tested the antifungal effect of 26 related compounds on 2 different organisms: a yeast and a mold. The data clearly shows that there...

    Started by GMIRCUS‎, 08-11-2013 08:12 AM
    • Replies: 2
    • Views: 1,221
    08-12-2013, 07:10 AM Go to last post
  33. Data analysis for Before/After experiment

    Hello all, In our laboratory we have tissue pieces that secrete a certain protein. After we subject them to treatment we measure the secreted...

    Started by maxina12‎, 08-04-2013 01:43 PM
    • Replies: 3
    • Views: 3,256
    08-11-2013, 04:34 PM Go to last post
  34. which analysis method

    Hello, I want to compare 1 control and 2 study groups (all of them different cell lines) for cell proliferation assay. For control group: ...

    Started by medbio‎, 08-07-2013 06:52 AM
    • Replies: 2
    • Views: 1,288
    08-11-2013, 09:26 AM Go to last post
  35. ROC problem

    I have a problem related to classifying results and performing an ROC analysis or something analagous. Here is my situation: I have data from...

    Started by mnd‎, 08-05-2013 12:03 PM
    • Replies: 0
    • Views: 1,350
    08-05-2013, 12:03 PM Go to last post
  36. Ordinal Logistic Regression

    Hello all I ran an ordinal logistic regression, my DV has 3 categories, and I ran it vs. a categorical IV with 5 categories (so the computer...

    Started by NN_STAT‎, 08-03-2013 12:51 PM
    • Replies: 0
    • Views: 1,864
    08-03-2013, 12:51 PM Go to last post
  37. Too many genes

    Hello all I have a data sheet, with a discrete dependent variable having 3 categories. I have a set of independent variables, some continuous,...

    Started by NN_STAT‎, 08-03-2013 04:32 AM
    • Replies: 2
    • Views: 1,422
    08-03-2013, 12:48 PM Go to last post
  38. I TOO have a question about surgical outcomes and data analysis!

    Hey everyone So Iím new here and I have a few questions about this new project Iíve been assigned to. Iíve worked with statistical analysis to some...

    Started by mjbarteau‎, 07-31-2013 06:23 PM
    • Replies: 4
    • Views: 1,551
    08-02-2013, 06:43 AM Go to last post
  39. Paired samples with competition

    Hi all, I have abit of a puzzle that at first may seem straightforward but I believe there is a complication. I have a paired design with each...

    Started by emily.stats‎, 07-30-2013 04:59 AM
    paired-t, puzzles
    • Replies: 3
    • Views: 1,712
    07-30-2013, 10:50 AM Go to last post
  40. Epidemiological Stats: Accepting/Rejecting a Null Hypothesis

    Hello, I'm a grad student looking for help with what is probably a very simple question to someone with the right knowledge. I'm trying to finish...

    Started by jack2013‎, 07-28-2013 10:17 PM
    • Replies: 6
    • Views: 2,494
    07-30-2013, 02:33 AM Go to last post
  41. WEKA classification - cut off points.

    Hi all, Apologies if this is very long winded, first time post on this forum. I am using protein data to predict disease status, using WEKA to...

    Started by HiAASZY007‎, 07-29-2013 09:13 AM
    • Replies: 0
    • Views: 3,372
    07-29-2013, 09:13 AM Go to last post
  42. Advice on linear mixed model on longitudinal data

    Hello, I have a longitudinal dataset of cumulative biomass from an experiment. The subjects have been exposed of 3 different treatments (LOW, MED,...

    Started by and0s‎, 07-28-2013 05:20 AM
    • Replies: 2
    • Views: 2,028
    07-28-2013, 10:14 AM Go to last post
  43. Alternative to McNemar's Test

    Hello all, I want to run the McNemar's Test for matched binary data, however my sample is small (n=10 pairs), and the normal approximation cannot...

    Started by NN_STAT‎, 07-15-2013 08:01 AM
    • Replies: 1
    • Views: 5,079
    07-24-2013, 12:32 PM Go to last post
  44. Question Which analysis should i use? Rgeression or ANOVA or any ....

    I am doing one analysis in Natural Science discipline: I have lots of data but know I don't know how can I analyze them. As I am not statistician:...

    Started by petersool‎, 06-28-2013 04:05 AM
    • Replies: 5
    • Views: 1,968
    07-20-2013, 02:35 AM Go to last post
  45. Number of subjects vs raters for Fleiss K- Urgent Help requested

    Would appreciate input. We are planning to test a new scoring tool that has 5 categories. We are sending out 3-4 video recorded cases to ~40 raters...

    Started by archj99‎, 07-19-2013 01:17 PM
    • Replies: 0
    • Views: 1,285
    07-19-2013, 01:17 PM Go to last post
  46. Hierarchical regression with partially nested variables

    I would like to do a logistic regression of vaccination coverage of, for example, HPV. Let's assume that we have 50 states (S). 30 states have an...

    Started by giordano‎, 07-19-2013 10:37 AM
    hierarchical regression, mixed effect, nested data
    • Replies: 0
    • Views: 1,232
    07-19-2013, 10:37 AM Go to last post
  47. what is the best statistical analysis ? outcome of surgery

    Dear All, I would like some advice on the most appropriate statistical analysis for some data I have. I have a data set which comes from a...

    Started by edmundfitz‎, 07-12-2013 04:31 AM
    • Replies: 6
    • Views: 2,115
    07-19-2013, 09:48 AM Go to last post
  48. Help! How to calculate difference between means +- SD

    Hi, My dissertation is due in the next 4 weeks, and what with it being distance learning and having other exams that I needed to do this year, I...

    Started by 5aboy‎, 07-17-2013 11:15 AM
    • Replies: 0
    • Views: 1,766
    07-17-2013, 11:15 AM Go to last post
  49. Demographics adjustment for combined counts

    Hello! My unit of observation was cities within a county. Since asthma counts were too small for each city, I decided to combine counts from...

    Started by phbios321‎, 07-15-2013 06:09 PM
    adjust, age, combine counts, demographics, standardize
    • Replies: 2
    • Views: 1,971
    07-16-2013, 10:55 AM Go to last post
  50. Paired survival analysis

    Hello all, I have 8 pairs of observations (each pair comes from the same person). For each observation I have 5 time points, and in each time...

    Started by NN_STAT‎, 07-15-2013 06:37 AM
    • Replies: 0
    • Views: 1,341
    07-15-2013, 06:37 AM Go to last post
  51. Normality check in factorial repeated measure anova

    Hi; I have 4(treatments)x6(time points) factorial in which time is a repeated measure. I want to check normality of data. I am confused, Should I...

    Started by mushtaq‎, 07-15-2013 04:35 AM
    • Replies: 0
    • Views: 1,403
    07-15-2013, 04:35 AM Go to last post
  52. Calibrating Priors for Bayesian Inference

    Thanks to suggestions by member Lowpro, I have been looking into using Bayesian inference analysis for a project I am working on. I am hacking...

    Started by hodag‎, 07-11-2013 11:43 AM
    • Replies: 0
    • Views: 1,197
    07-11-2013, 11:43 AM Go to last post
  53. Nearest neighbor matching for bivariate outcomes?

    Hi all, I'm new to nearest neighbor matching. I've been using it to analyze data with continuous outcomes; can this technique also be used for...

    Started by goldenbear‎, 07-10-2013 04:39 PM
    • Replies: 1
    • Views: 1,397
    07-10-2013, 05:57 PM Go to last post
  54. Mixed Model Nested Anova or Two sample test?

    Hello Forum Participants, My dissertation research evaluates the effect of a hormone on the epithelium. My data was obtained from a clinical trial...

    Started by cbell723‎, 07-02-2013 11:10 PM
    clinical trial, nested anova, two sample tests
    • Replies: 4
    • Views: 2,504
    07-10-2013, 07:00 AM Go to last post
  55. Question on 2-way ANOVA stat use and interpretation

    Hi everyone! I am currently working on publishing an article from my Masters thesis. I had real trouble with the statistics section which was also...

    Started by ducksmad‎, 07-06-2013 11:12 PM
    anova, interactions, repeated measures anova, research, two way anova
    • Replies: 5
    • Views: 2,537
    07-09-2013, 08:23 AM Go to last post
  56. Statistical analysis: Comparing effects of drug doses on blood glucose over time

    Hi all, New user and new to biostats so please go easy on me! I am working on a project where I am determining the effects of drug doses on...

    Started by Khodjakov‎, 07-08-2013 01:32 PM
    • Replies: 3
    • Views: 4,419
    07-08-2013, 05:18 PM Go to last post
  57. Sample Size Determination for a Case Control Study

    I am looking for 3 genetic polymorphisms in diseased versus control subjects. I found cases and I collected some controls. I wanted to check if my...

    Started by slowvt‎, 07-07-2013 03:18 AM
    • Replies: 0
    • Views: 1,374
    07-07-2013, 03:18 AM Go to last post
  58. Adjusting for repeat-test-exposure bias in diagnostic accuracy studies

    I'm conducting a metaanalysis pertaining to diagnostic accuracy of an index test compared to the reference standard, and for my question on this...

    Started by Borazja‎, 07-04-2013 03:50 PM
    diagnostic accuracy
    • Replies: 0
    • Views: 1,690
    07-04-2013, 03:50 PM Go to last post
  59. Statistical test - for comparing values obtained from fit of a physical model

    Hey guys, This is my problem. I am analyzing fluid flow profiles in biological samples. I have two conditions: wild type and a gene knockdown. I...

    Started by sundar‎, 07-04-2013 10:29 AM
    • Replies: 2
    • Views: 1,399
    07-04-2013, 12:29 PM Go to last post
  60. Variable creation for survival analysis

    I have a spss data set in which post abortion women are followed up for 12 months, and their use of contraceptives are asked for every month. So in...

    Started by deeps‎, 07-03-2013 03:26 AM
    • Replies: 0
    • Views: 1,191
    07-03-2013, 03:26 AM Go to last post

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