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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Why use bivariate and then multivariate to test variables with P value of 0.10?

    Hi guys, I am confused by a paper that is using bivariate analysis to variables and if the P value is 0.10 or less, they use those variables in a...

    Started by runnyeggsham‎, 03-19-2012 11:41 AM
    bivariate multivariate
    • Replies: 1
    • Views: 3,820
    04-09-2012, 09:39 PM Go to last post
  2. Post ROC curves - an appropriate use?

    Hi all, I am new to ROC curves. My only experience is using them to examine tests for a specific disease, however I wonder if my plans below are...

    Started by dhmallon‎, 04-06-2012 06:35 PM
    • Replies: 3
    • Views: 1,609
    04-08-2012, 06:18 PM Go to last post
  3. finding total exposure from continous and categorical variables

    Hi all :wave: I need a little help!! I have 3 variables. 1st- age at 1st exposure, continuous 2nd and 3rd- categorical with categories as...

    Started by praj‎, 04-07-2012 05:53 PM
    • Replies: 4
    • Views: 1,442
    04-07-2012, 07:25 PM Go to last post
  4. Application of SVM-RFE

    I currently have a proteomics dataset comparing two cell lines (WM and 1205) that have been analyzed in triplicate. I was hoping to apply the...

    Started by mada2009‎, 04-05-2012 03:14 PM
    • Replies: 0
    • Views: 1,619
    04-05-2012, 03:14 PM Go to last post
  5. help with standard deviation

    i have data on the duration of a procedure that ranges from 0.10 to 48 months with a mean of 8 and standard deviation of 13. this would imply that...

    Started by gideon794‎, 04-03-2012 10:04 AM
    • Replies: 4
    • Views: 1,753
    04-03-2012, 05:51 PM Go to last post
  6. Permutational ANOVA

    Hi all - this is my first post :) I am an environmental professional tasked with the problem of developing sensitive tests of environmental...

    Started by Shiello1‎, 04-02-2012 04:00 AM
    • Replies: 4
    • Views: 5,465
    04-02-2012, 07:26 AM Go to last post
  7. How to do post hoc tests in logistic regression?

    I looked at whether participants recycled after being subjected to a given message. There were three groups: a Control group, group A, and group B. ...

    Started by ionpattern‎, 03-29-2012 08:13 PM
    logistic regression, post hoc test
    • Replies: 2
    • Views: 9,774
    04-01-2012, 07:40 PM Go to last post
  8. interpreting random effects

    I have have measured the trait frequency for a "mountain" associated allele across a number of sites and years. In my (glmer) model I have summarized...

    Started by keithwlarson‎, 04-01-2012 06:31 AM
    mixed models, random effects
    • Replies: 0
    • Views: 2,819
    04-01-2012, 06:31 AM Go to last post
  9. desperate need of help for my data

    :wave: I'm a university student trying to analyze some data I have for river dolphins. I did some mistake and assumed that the data (count data)...

    Started by cristiancjb‎, 04-01-2012 06:13 AM
    • Replies: 0
    • Views: 1,207
    04-01-2012, 06:13 AM Go to last post
  10. Detecting outlier sample sites

    I have binomial frequency data for an allele associated with populations living in mountainous. These mountains run north to south where sites are...

    Started by keithwlarson‎, 03-31-2012 05:45 AM
    glm, methodology, outliers, predictive model
    • Replies: 1
    • Views: 1,354
    03-31-2012, 09:12 AM Go to last post
  11. Logistic regression

    Hello everyone... I'm trying to create a graph similar to the FIG. I did the analysis in proc logistic and I found a quadratic effect and I...

    Started by Dinan‎, 03-29-2012 11:45 AM
    • Replies: 5
    • Views: 2,111
    03-29-2012, 12:36 PM Go to last post
  12. Analysis of variance in data with ordinal output

    Hi there. I am a new member with a query relating to the output from a clinical trial. I have four groups of patients (30 in each group) who have...

    Started by DrJon‎, 03-27-2012 06:51 AM
    • Replies: 1
    • Views: 2,960
    03-27-2012, 04:03 PM Go to last post
  13. Mutation rates

    Hello, I am able to introduce specific targeted mutations into a cell. When I perform an experiment, in which I only introduce 1 specific mutation...

    Started by Koen27‎, 03-26-2012 02:36 AM
    • Replies: 0
    • Views: 1,156
    03-26-2012, 02:36 AM Go to last post
  14. Is my design correct ?

    Hello I'm doing proposal now The title is " The differences between Hearing test result before and after treatment" n i decide to choose cross...

    Started by ditikhsan‎, 03-23-2012 07:06 AM
    • Replies: 2
    • Views: 1,520
    03-23-2012, 11:19 AM Go to last post
  15. 2-way repeated measures ANOVA with 2 many repeated measures

    Hi, I am looking a several genes and I have measured a value for several exons of these genes (range: 4 to 87). I am looking at the difference...

    Started by mousme‎, 03-23-2012 11:12 AM
    • Replies: 0
    • Views: 1,665
    03-23-2012, 11:12 AM Go to last post
  16. multivariate ordinal probit regression with vglm()

    Hello, all. I'm investigating the rate at which skeletal joint surfaces pass through a series of ordered stages (changes in morphology). Current...

    Started by @nthRo‎, 03-22-2012 03:20 PM
    multivariate regression, probit
    • Replies: 0
    • Views: 1,263
    03-22-2012, 03:20 PM Go to last post
  17. Analysis of respiration

    I am trying to analyze egg respiration data. I have 7 eggs that were measured over a 10 day period. I have data from 45 minute runs, that I have...

    Started by Gwendolyon‎, 03-20-2012 06:39 PM
    biology, help please, mean square error, residual, t-test
    • Replies: 0
    • Views: 1,644
    03-20-2012, 06:39 PM Go to last post
  18. multi dimensional and correlated data

    Hello, I need to analyze a data-set, containing one response variable, a binary one (sick and healthy patients). In addition, I have hundreds of...

    Started by NN_STAT‎, 03-15-2012 07:27 AM
    • Replies: 1
    • Views: 1,575
    03-15-2012, 10:23 AM Go to last post
  19. Best test to use in heart transplant patients

    I've done a retrospective analysis of 94 heart transplant patients. They are devided into four groups according to there donor/recepient CMV...

    Started by Rybnik‎, 03-14-2012 11:44 AM
    • Replies: 2
    • Views: 1,600
    03-14-2012, 01:49 PM Go to last post
  20. statistics on sigmoidal fitting parameters

    Hi, I have an experiment with three treatments (triplicates). I am doing a sigmoidal fitting to the data so my final parameters are: a, b, c. Is...

    Started by ashz‎, 03-14-2012 05:29 AM
    • Replies: 0
    • Views: 1,455
    03-14-2012, 05:29 AM Go to last post
  21. Is anybody familiar with GSEA?

    I've been trying to run through their tutorials but even when I think I've set up everything exactly as they have it on the site, I don't get any...

    Started by spidercano‎, 03-13-2012 08:46 PM
    • Replies: 0
    • Views: 755
    03-13-2012, 08:46 PM Go to last post
  22. What test to use for a dose-response curve?

    Hi everybody! I'm doing my master thesis in genetics and my statistical training did not go beyond t-test and chi-square, so I'm very sorry if my...

    Started by Walli‎, 03-12-2012 08:04 PM
    • Replies: 0
    • Views: 1,712
    03-12-2012, 08:04 PM Go to last post
  23. Needing a bit of help with sample sizes :)

    Hello, I'm new here so apologies if this is a simple question, I have tried a search online and here, but I'm am rather stuck. I am trying to...

    Started by ladybug123‎, 03-12-2012 02:10 PM
    confused, help please, multiple variables, pairwise comparison, sample size
    • Replies: 0
    • Views: 1,200
    03-12-2012, 02:10 PM Go to last post
  24. classification equation

    Hello everybody, I'm working on several (7) classes, reying to assign to each class my subjects (total=500) on the basis of 46 ordinal (0,1,2,3,4)...

    Started by marco77‎, 03-06-2012 10:26 AM
    • Replies: 0
    • Views: 1,284
    03-06-2012, 10:26 AM Go to last post
  25. Risk percentage: Need help in method to find linear predictor Cox proportional hazard

    Dear All, Please help me with method calculate linear predictor x from this table...will be grateful for any pointers received...thanks in advance

    Started by graced‎, 03-06-2012 02:42 AM
    • Replies: 0
    • Views: 1,419
    03-06-2012, 02:42 AM Go to last post
  26. Time-series data and fixed levels of similarity in Primer

    Hi, Apologies if this is not posted in the right section. I am currently in the process of analyzing a time-series dataset where the same...

    Started by vanguard605‎, 03-01-2012 08:14 PM
    • Replies: 4
    • Views: 3,570
    03-06-2012, 02:41 AM Go to last post
  27. Interpreting Hazard Ratio=0

    Hello Folks: While running a simple PHREG analysis (model duration*censorvar(1)=trt) on one of my subgroups, I encounter a value of Zero for the...

    Started by milan_stats‎, 02-28-2012 03:28 PM
    • Replies: 3
    • Views: 9,095
    03-05-2012, 07:11 AM Go to last post
  28. What's the best test?

    Dear all, Just wondering which statistical test would be most appropriate to analyze this data. I am comparing systolic blood pressure over...

    Started by realhighh‎, 03-04-2012 07:47 AM
    • Replies: 4
    • Views: 4,029
    03-05-2012, 04:57 AM Go to last post
  29. Neuron Morphology: Sholl Analysis Statistics

    Hello all, I have generated a plot illustrating the number of dendrites at various distances from the cell body, known as Sholl Analysis. It is...

    Started by james.jones08‎, 03-05-2012 03:06 AM
    • Replies: 0
    • Views: 5,296
    03-05-2012, 03:06 AM Go to last post
  30. Identifying the experimental unit in ANOVA analyses

    Hi all, I am preparing an experimental design for an aquaculture experiment and have read several papers that have conducted similar trials with...

    Started by DeanP‎, 03-01-2012 10:33 PM
    • Replies: 1
    • Views: 3,293
    03-01-2012, 11:09 PM Go to last post
  31. Scheirer-Ray-Hare test

    Hi, can I use a Scheirer-Ray-Hare test on an analysis where one factor has 2 levels and the other one 11?? A more general question would be can I use...

    Started by mousme‎, 03-01-2012 12:50 PM
    • Replies: 0
    • Views: 3,379
    03-01-2012, 12:50 PM Go to last post
  32. Confidence interval for correlated proportions, one from a subgroup of the total

    Hi, I found a derivation for a closed-form variance estimate for the difference of 2 correlated proportions, one of which is from a subgroup of the...

    Started by Suzannah‎, 02-28-2012 08:10 PM
    • Replies: 0
    • Views: 1,586
    02-28-2012, 08:10 PM Go to last post
  33. Comparing two correlated statistics

    I need to compare two betas that are calculated in the same sample and so are not independent. the betas are estimates of cognitive change over 20...

    Started by PetiteG‎, 02-10-2012 05:32 AM
    • Replies: 1
    • Views: 1,242
    02-28-2012, 07:57 PM Go to last post
  34. modeling temporal variation

    Hi I have 6 years of patient-level data and I'm using a hierachical (2-level) regression model. Could anyone suggest ways to model the temporal...

    Started by longrob‎, 01-05-2012 09:48 AM
    multilevel model, random effects
    • Replies: 1
    • Views: 1,341
    02-27-2012, 02:18 PM Go to last post
  35. How best to analyze this data?

    I am crossposting this from the main forum, I hope that is not a problem... I'm sure I learned about this at one time, but I'm a little rusty....

    Started by dingdong‎, 02-26-2012 02:29 PM
    • Replies: 1
    • Views: 1,340
    02-26-2012, 02:33 PM Go to last post
  36. Test for treatment effects over time with repeated measures

    Hi, I am a medical researcher and we are trying to design an experiment to test the effects of 5 different analgesic combinations against placebo....

    Started by RikT‎, 02-24-2012 06:50 AM
    • Replies: 0
    • Views: 1,406
    02-24-2012, 06:50 AM Go to last post
  37. Exclamation Need Help Graphing Multiple Graphs into One Graph

    Hello, I am an undergraduate student in biology. I have not yet completed a statistics course but I do have basic familiarity with graphing in...

    Started by nnayyar‎, 02-23-2012 11:18 AM
    • Replies: 0
    • Views: 1,477
    02-23-2012, 11:18 AM Go to last post
  38. How to adjust data of confounding variables adjusting diabetes to BMI and age

    I am doing a study of pregnant diabetes women. There are 3 types Type 1 , 2 and gestational. Then various ages and bmis. Outcomes study include type...

    Started by FSNWRM‎, 02-21-2012 01:34 AM
    • Replies: 6
    • Views: 11,609
    02-22-2012, 08:41 AM Go to last post
  39. nonparametric test for reaction times

    Dear all, I have problems with analysing the following data set consisting of reaction times: 20 subjects performed alltogether 3 tasks...

    Started by Nazuna‎, 02-19-2012 11:11 AM
    • Replies: 2
    • Views: 2,334
    02-21-2012, 05:21 AM Go to last post
  40. Is it really significant ?

    Hello, I ran a series of 100 t-tests and 100 Mann Whitnety U test, I had an "array" of 100 variables and I compare their values between healthy...

    Started by NN_STAT‎, 02-05-2012 02:47 PM
    • Replies: 12
    • Views: 3,575
    02-18-2012, 02:52 PM Go to last post
  41. WinBugs to model West Nile Virus

    :wave:v Anyone experienced in using WinBugs for modeling spatial and temporal disease data? I needed some reference on how to write the model of...

    Started by Archie‎, 02-17-2012 12:38 PM
    • Replies: 4
    • Views: 2,579
    02-17-2012, 10:30 PM Go to last post
  42. Can I compare 4 response variables in one test?

    My study has 6 Locations and each location was subsampled by setting up 6 Subplots. The number of subjects in each subplot (and ultimately location)...

    Started by SeatOFpants‎, 02-16-2012 12:15 PM
    • Replies: 0
    • Views: 1,415
    02-16-2012, 12:15 PM Go to last post
  43. How to calculate the Standard deviation of the ratio of two means

    Hi I need to calculate the standard deviation of the ratio between two average values (I have the standard deviation of each average). Steps: -...

    Started by mromano‎, 02-13-2012 10:51 AM
    • Replies: 2
    • Views: 20,221
    02-15-2012, 05:08 PM Go to last post
  44. Significantly higher ?

    Hi, This is probably a very basic question! See attached pdf. This is a bar graph representing the counts in each sample. I have approx. 60...

    Started by sjlabrie‎, 02-14-2012 11:47 AM
    • Replies: 8
    • Views: 3,668
    02-15-2012, 03:03 PM Go to last post
  45. equal or unequal sample size ?

    I have a simple theoretical question... Let's say I have a sample of 30 subjects from group A and 150 from group B, and I want to run a t-test. ...

    Started by NN_STAT‎, 02-14-2012 07:56 AM
    • Replies: 6
    • Views: 12,511
    02-15-2012, 09:06 AM Go to last post
  46. Outlier detection

    Does anybody have any ideas on how to detect outliers in multidimensional data? I have a huge amount of proteomics data, and I'm unsure of the...

    Started by jmr‎, 02-09-2012 11:14 AM
    • Replies: 2
    • Views: 1,508
    02-09-2012, 12:31 PM Go to last post
  47. mauchly's test

    I am analysing the results of my research. In this research I has a sample size of 4 and I was testing the effect of 3 factors (light, feeding and...

    Started by Saskia‎, 02-09-2012 04:29 AM
    • Replies: 1
    • Views: 4,297
    02-09-2012, 09:40 AM Go to last post
  48. Binary panel data analysis question

    Dear, I am trying to analyze an unbalanced panel data set. It contains yearly data on a fairly large number of patients and spans almost twenty...

    Started by kimpeeters‎, 02-08-2012 04:11 AM
    • Replies: 1
    • Views: 2,028
    02-08-2012, 03:41 PM Go to last post
  49. Relationship over time, depiste loss of participants

    Here is the problem: I have 56 patients in my sample, all of which have variable lengths of stay so they exit the ED at irregular times. Nurses...

    Started by varndellw‎, 02-06-2012 05:42 PM
    • Replies: 2
    • Views: 2,650
    02-07-2012, 05:21 PM Go to last post
  50. qPCR relative expression significance

    Hy people, my first post here and it has a lot of questions. I'm currently working on my master thesis in molecular genetics doing mainly qPCR...

    Started by Nast‎, 02-07-2012 10:28 AM
    • Replies: 0
    • Views: 4,387
    02-07-2012, 10:28 AM Go to last post
  51. Question What sort of statistics can I do in my project (Study with control/experiment group

    Hello, What sort of statistics I can do in my project ( see details below) and how I can enhance it further with incorporating research too. I...

    Started by siot2012‎, 02-06-2012 04:46 PM
    • Replies: 1
    • Views: 3,415
    02-06-2012, 06:17 PM Go to last post
  52. Chi-Square Question

    I want to see if one population of trees has a significantly lower density of seedlings than two other populations of trees becasue it certainly...

    Started by utahensis‎, 02-04-2012 05:19 PM
    • Replies: 0
    • Views: 1,497
    02-04-2012, 05:19 PM Go to last post
  53. Regression analysis q-q plots and residual histogram

    Hi, Would someone mind taking a look at my data and see if it's close enough to normality for a regression analysis. If they aren't would anyone...

    Started by mr_bennyc‎, 02-03-2012 11:13 AM
    • Replies: 2
    • Views: 4,014
    02-03-2012, 11:35 AM Go to last post
  54. Proportional Hazards Regression the Best Option for Me?

    Hi all, I'm planning to collect data on an ecological momentary assessment predicting assessing two psychological dimensions. Basically, I will...

    Started by njacobson88‎, 01-26-2012 03:26 PM
    • Replies: 4
    • Views: 1,757
    02-02-2012, 11:45 AM Go to last post
  55. Which statistical test should i use

    Hi all, I ran an experiment and measured my dependant variable (protein expression) in different time points with different animals. I want to...

    Started by sharonin1‎, 02-02-2012 08:09 AM
    • Replies: 1
    • Views: 1,779
    02-02-2012, 09:41 AM Go to last post
  56. Statistics with Qualitative Data...Chi-Square and Kruskal?

    Hello! I am looking for some help as I am new to the qualitative analysis. We have data from 3 countries, and I am simply trying to see if there are...

    Started by em1886‎, 01-30-2012 09:18 AM
    • Replies: 1
    • Views: 2,497
    01-30-2012, 04:04 PM Go to last post
  57. From p-value to sensitivity

    Hi All! I've devised a statistical way to weigh up evidence for and against a positive diagnosis. My null hypothesis is that there is that the...

    Started by Johann Kotze‎, 01-27-2012 06:57 AM
    • Replies: 4
    • Views: 5,672
    01-30-2012, 04:22 AM Go to last post
  58. [SOLVED] Medical Assignment

    I am working on a school assignment on medical data. I am trying to determine what test/methods to use on this assignment. I am using the date/time...

    Started by Medic49‎, 12-21-2011 12:25 AM
    • Replies: 10
    • Views: 2,527
    01-29-2012, 09:49 PM Go to last post
  59. Best test for multiple interventions

    I am hoping someone can help me with analysis of a small data set. I am trying to determine the effects of different interventions on a single...

    Started by JohnAndrews‎, 01-28-2012 05:51 PM
    • Replies: 2
    • Views: 1,795
    01-28-2012, 05:59 PM Go to last post
  60. small sample size

    Hi everyone! Nice to meet people do same things on the web:) Here the question: I have independent two group of patients first group have 10...

    Started by furkan‎, 01-26-2012 10:19 AM
    compare groups, samle size, statistical test
    • Replies: 2
    • Views: 1,973
    01-27-2012, 02:17 AM Go to last post

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