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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Anova

    Hello! I have a problem with data analysis and don't know which method to use. Here is a description of my problem: I have cells that have been...

    Started by iced_eax‎, 07-27-2010 07:56 PM
    • Replies: 0
    • Views: 1,990
    07-27-2010, 07:56 PM Go to last post
  2. Odds Ratio vs. P-value

    Hi Everyone, I am a Master's student in South Africa investigating genetic susceptibility to tuberculosis. I was running a haplotype analysis and...

    Started by canadianamazon‎, 07-27-2010 10:10 AM
    • Replies: 2
    • Views: 8,729
    07-27-2010, 11:08 AM Go to last post
  3. 3-group analysis

    Hello, I have little project, and today doubts just brought me down. I have sample of 25 patients, and 3 types of disease (a person can have more...

    Started by yooguruto‎, 07-26-2010 01:25 PM
    • Replies: 0
    • Views: 3,382
    07-26-2010, 01:25 PM Go to last post
  4. Possible Interaction?

    Hi! I've fit the following logistic regression model: Y = waking up with a soar throat (y=1 if yes, y=0 if no) T = type of device (t=1 if type...

    Started by jamesmartinn‎, 03-26-2010 12:18 AM
    • Replies: 2
    • Views: 3,098
    07-25-2010, 10:22 PM Go to last post
  5. odds ratio question

    I have the following data: Group A starting in Jan.: Pass: 40, Fail: 60 Group B starting in Feb.: Pass: 90, Fail: 50 Group C starting in...

    Started by basasguru‎, 07-24-2010 11:34 PM
    • Replies: 2
    • Views: 2,744
    07-25-2010, 09:59 PM Go to last post
  6. Outlier

    I'd like to ask you a question about some data I have. I have measured the expression of a gene under different conditions. For each condition the...

    Started by iced_eax‎, 07-25-2010 07:26 PM
    • Replies: 0
    • Views: 3,461
    07-25-2010, 07:26 PM Go to last post
  7. Question about interactions in regression

    So recently, I was told that when using regression with interactions, a main term must always be put in the model. I brought up a situation where I...

    Started by Link‎, 07-09-2010 03:14 PM
    • Replies: 2
    • Views: 2,680
    07-11-2010, 05:54 PM Go to last post
  8. Correcting for measurement error in logistic regression?

    Hi guys, Myself and a co-author have recently submitted a journal article assessing a particular criminological theory's adequacy in terms of...

    Started by CowboyBear‎, 07-07-2010 11:29 PM
    • Replies: 5
    • Views: 6,294
    07-08-2010, 07:15 PM Go to last post
  9. censoring provide one example

    Hi there, Censored variables come up usually in survival analysis (also in reliability) where the time to event is censored. Thus, usually (or I...

    Started by leo nidas‎, 07-06-2010 11:34 AM
    • Replies: 7
    • Views: 6,524
    07-08-2010, 06:55 AM Go to last post
  10. Biometric analysis help

    Hello, Im attempting to perform an analysis on a number of characteristics of a subject to identify them. For any given user, I have anywhere...

    Started by b00kworm‎, 05-27-2010 11:36 PM
    • Replies: 5
    • Views: 3,132
    06-23-2010, 09:38 AM Go to last post
  11. Help with a molecular biology project

    Hello guys I am doing my phd research in molecular biology. I am totally illiterate in statistics that is why i am facing some real problems in my...

    Started by dr.m.umer‎, 06-16-2010 03:37 PM
    • Replies: 3
    • Views: 3,689
    06-18-2010, 02:08 PM Go to last post
  12. Seeking basic analysis help

    I have a question regarding an analysis of the number of defects found in products over a certain time period and whether or not a method to fix...

    Started by abelian‎, 06-15-2010 09:00 AM
    • Replies: 1
    • Views: 3,554
    06-15-2010, 10:39 AM Go to last post
  13. median survival time

    Hello, I'm trying to plot a survival curve and I also need median survival time and 95%CI. I specifically need the 95% CI which is not easy to...

    Started by noob‎, 06-06-2010 05:08 PM
    • Replies: 8
    • Views: 15,575
    06-13-2010, 01:28 AM Go to last post
  14. logistic regression model

    hello everyone still a newbie in statistics... I made a regression model with binary logistic regression because i have a dichotomous outcome...

    Started by Lotjeo‎, 06-01-2010 02:09 AM
    • Replies: 2
    • Views: 4,271
    06-01-2010, 11:06 AM Go to last post
  15. Can you calculate the odds ratio for a 2X3 Chi Square?

    I know technically you can do the calculation, but what I really want to know is does this give you any statistically relevent information that you...

    Started by billkarr‎, 05-15-2010 08:19 AM
    • Replies: 1
    • Views: 10,334
    05-15-2010, 06:03 PM Go to last post
  16. Need help ...lost, re: clinical research

    Hello, First, let me thank you for looking at this post. My question is we are trying to see the effect of X drug on fracture rate. In the...

    Started by bisphos00‎, 05-06-2010 09:05 AM
    • Replies: 2
    • Views: 3,001
    05-10-2010, 09:20 AM Go to last post
  17. any Biostatistician around?

    Hi, I'm wondering if there's any Biostatistician around in this forum? Looking for a mentor and an ally here. :wave: -anggraini_13

    Started by anggraini_13‎, 04-28-2010 04:49 AM
    • Replies: 1
    • Views: 2,605
    05-03-2010, 02:49 AM Go to last post
  18. Missing data: Use of the indicator method

    Hello everyone, My question pertains to the treatment of missing data and use of the indicator method in regression analyses (i.e. creating either...

    Started by Nick5930‎, 04-27-2010 10:59 PM
    • Replies: 0
    • Views: 4,675
    04-27-2010, 10:59 PM Go to last post
  19. Unbalanced Panel data (FEM , REM, or Pooled regression)

    Hi, I have unbalanced panel data. Using SAS, the null hypthesis of Hausman Test was not rejected (means the random effects model is better than...

    Started by tantan‎, 04-24-2010 10:44 AM
    • Replies: 0
    • Views: 9,458
    04-24-2010, 10:44 AM Go to last post
  20. Help with diagnostic test analysis

    Hi, Iím doing a project with a physician in a hospital and I am hoping to run some statistics on a data set I have, and Iím realizing now how...

    Started by lostandconfused‎, 04-21-2010 04:21 PM
    • Replies: 0
    • Views: 3,307
    04-21-2010, 04:21 PM Go to last post
  21. Help interpreting a binary logistic regression

    Hi all, I've a question about interpreting the results of a binary logistic regression. I'm using SPSS for my analysis. I've one dependent which...

    Started by blastStu‎, 04-20-2010 04:05 AM
    • Replies: 2
    • Views: 5,732
    04-20-2010, 09:53 AM Go to last post
  22. Interpret the coefficient

    In a study of melanoma, survival times in months were obtained for 214 patients. The following potential explanatory variables were considered: sex...

    Started by gla.ac‎, 04-07-2010 09:56 AM
    • Replies: 0
    • Views: 4,793
    04-07-2010, 09:56 AM Go to last post
  23. Power calculations help..

    Hello all, I don't suppose i can ask a question on power calculations? I've just conducted a RCT involving two student groups one undertaking...

    Started by Logan Manikam‎, 03-24-2010 04:06 PM
    • Replies: 4
    • Views: 5,558
    03-30-2010, 09:39 PM Go to last post
  24. Question Strengths of mixed model

    Hello forum, I am doing a clinical trial with crossover design and repeated measurements. (4 treatment groups and 11 subjects.) I have been...

    Started by jensh‎, 03-25-2010 08:21 AM
    • Replies: 0
    • Views: 3,010
    03-25-2010, 08:21 AM Go to last post
  25. Bacterial death rate statistics - I need help!

    My masters dissertation focusses on bacterial survival time on paper surfaces, using E.coli and S.aureus When plotting log cell count against time...

    Started by sdans‎, 03-24-2010 03:27 PM
    • Replies: 2
    • Views: 3,963
    03-24-2010, 07:09 PM Go to last post
  26. Question Help with GLM/logit diagnostics and result interpretation

    I have this complex toy example trough which I'm trying to learn how I can apply generalized linear models (a logit model to be exact where the...

    Started by Isac3‎, 02-20-2010 11:16 AM
    • Replies: 3
    • Views: 7,224
    03-23-2010, 12:24 AM Go to last post
  27. Positive predictive value

    I've conducted an experiment where I calculated a positive predicted value, what statistical test can I use to assess these values?

    Started by somba‎, 03-16-2010 12:29 PM
    • Replies: 1
    • Views: 5,809
    03-17-2010, 05:43 AM Go to last post
  28. Comparing survival curves while controlling for confounding factors

    I am trying to compare three kaplan-meier survival curves. I am under the impression that a log-rank test would normally be used to accomplish this....

    Started by canvaspants‎, 03-16-2010 11:43 PM
    • Replies: 1
    • Views: 5,406
    03-17-2010, 01:55 AM Go to last post
  29. Statistical test for sensitivity and specificity

    Hi everyone, I'll make this as quick and easy as possible :) I've carried out a project where I compare the efficiency of two tests used for the...

    Started by somba‎, 02-26-2010 10:40 AM
    • Replies: 2
    • Views: 7,061
    03-16-2010, 01:52 AM Go to last post
  30. Simple Logistic Regression

    Five different doses of insecticide were applied under standardized conditions to an insect species. The data are as followed: Dose (mg/l): 2.6...

    Started by jamesmartinn‎, 03-11-2010 08:18 PM
    • Replies: 2
    • Views: 3,059
    03-12-2010, 01:52 PM Go to last post
  31. How to make a heatmap in R for a microarray data?

    Hi guys, I have been given a microarray data for which I need to figure out a heatmap. Unfortunately I have never had a chance and experience in...

    Started by LigongKarlChen‎, 03-08-2010 11:35 AM
    • Replies: 2
    • Views: 13,053
    03-08-2010, 03:16 PM Go to last post
  32. Odds Ratio and Confidence interval for McNemar's Test

    How would you calculated the odds ratio and confidence intervals for a McNemars test applied to a 2 ◊ 2 contingency table on matched, case controled...

    Started by MillyMay‎, 03-08-2010 12:15 PM
    • Replies: 0
    • Views: 5,695
    03-08-2010, 12:15 PM Go to last post
  33. Survival time of components - what approach

    Hey, Some electronic components have had their time to breakdown x, recorded. During manufacturing they have been hardened for different amounts...

    Started by Daviate‎, 02-28-2010 01:20 PM
    • Replies: 0
    • Views: 2,746
    02-28-2010, 01:20 PM Go to last post
  34. Confidence Intervals / Chi Square Methodology

    I'm working on a project for school and I need some help determining how to best understand the following situation (any help is greatly...

    Started by cardiffgiant‎, 02-20-2010 01:08 PM
    • Replies: 2
    • Views: 3,045
    02-22-2010, 07:28 AM Go to last post
  35. G*Power Apriori Power Calculation

    I am wanting to do a power calculation using G*Power. I want to know the sample size when I am intending to do some Multinominal Logistic Regression...

    Started by fraenzchen1‎, 02-16-2010 06:04 PM
    • Replies: 0
    • Views: 6,691
    02-16-2010, 06:04 PM Go to last post
  36. Logistic regression

    Hi, I am stuck with my assignment question for awhile, need some advise on solving. Here is the question: The following logistic model (Model A)...

    Started by blueycool‎, 02-08-2010 10:24 PM
    • Replies: 4
    • Views: 3,571
    02-11-2010, 03:09 AM Go to last post
  37. Question P values in Medical Writing

    My apology for this simple question but it's one I have run into before and would like some assistance with. The following was posted on a medical...

    Started by medwriter‎, 02-10-2010 08:34 AM
    • Replies: 3
    • Views: 6,838
    02-10-2010, 10:58 AM Go to last post
  38. interpreting logistic regression

    I am having a tough time interpreting output in terms of what the coefficients and odds ratio say about the estimated effect. For example, say you...

    Started by traumaprof‎, 01-30-2010 09:14 PM
    • Replies: 1
    • Views: 5,152
    01-31-2010, 07:57 AM Go to last post
  39. Survival Analysis

    Just a quick question on running a survival analysis. Regarding the Time to Event variable, how is it coded? For example, if I'm measuring...

    Started by Cagoguy‎, 01-25-2010 03:14 PM
    • Replies: 4
    • Views: 4,201
    01-27-2010, 08:21 AM Go to last post
  40. Contingency Tables/Chi Square Test

    Hi all, Please help statistics gurus! I've searched through some of the postings but couldn't find the specific answer I was looking for. If I...

    Started by apdragon‎, 01-08-2010 11:30 PM
    • Replies: 2
    • Views: 3,538
    01-10-2010, 06:19 PM Go to last post
  41. Ancova

    Hi, I have a question regarding ANCOVA. I feel it might be a stupid one but there you go. I have 2 groups (men and women) for which I am scoring a...

    Started by mousme‎, 01-08-2010 11:48 AM
    • Replies: 1
    • Views: 2,749
    01-08-2010, 12:23 PM Go to last post
  42. Question ROC curve from logisitc regression Bootstrap analysis in Stata 9.2

    Hello, I am doing an analysis to predict an outcome (death) from a database. The model is suposed to be used to predict which children need immediate...

    Started by MRH‎, 11-16-2009 10:13 PM
    • Replies: 5
    • Views: 9,364
    12-18-2009, 03:27 PM Go to last post
  43. power analysis

    dear friends hi! i am relatively new in the site so plz forgive any errors of me!! i have this problem: i am doing a case control study, trying to...

    Started by melekos‎, 12-11-2009 01:10 PM
    • Replies: 0
    • Views: 2,771
    12-11-2009, 01:10 PM Go to last post
  44. Logistic Regression (Odds Ratio)

    Hi, Question: In terms of the risk reduction as conveyed by the odds ratio, one year of age corresponds to how many pounds of initial weight? Is...

    Started by rlin2009‎, 12-04-2009 08:12 AM
    • Replies: 0
    • Views: 3,904
    12-04-2009, 08:12 AM Go to last post
  45. logistic regression interaction term - change between main effects and full model

    Hello, I would appreciate your help with this problem. I have a binary logistic regression model. The main effects model includes female (coded...

    Started by Tucker04‎, 12-01-2009 03:32 PM
    • Replies: 0
    • Views: 5,689
    12-01-2009, 03:32 PM Go to last post
  46. What implications does the relationship between sensitivity/sentificity have?

    It's the last question in my assignment. I have already worked out that the sensitivity and specificity of a test go in opposite directions depending...

    Started by MickQ‎, 11-26-2009 04:43 PM
    • Replies: 0
    • Views: 2,240
    11-26-2009, 04:43 PM Go to last post
  47. Logistic Regression Help

    I am having difficulty interpreting the significance of this output: Attainment and still enrolled (Dependent variable) Time the job executed...

    Started by LogRegMan‎, 10-23-2009 05:22 PM
    • Replies: 3
    • Views: 3,519
    10-24-2009, 05:57 PM Go to last post
  48. logistic regression intercept is negative and not significant

    Hi, I have a logistic regression question. My dependent variable is coded 0, 1. When I run my models, the intercept (constant) is negative, and...

    Started by Tucker04‎, 10-22-2009 01:42 PM
    • Replies: 3
    • Views: 20,332
    10-23-2009, 11:52 AM Go to last post
  49. Ordinal Regression or Probit Analysis?

    Hi Guys, I am currently researching the survival rates of hedge funds. I am trying to find the effect of certain fund characteristics (risk,...

    Started by jodapo‎, 09-27-2009 10:45 AM
    • Replies: 0
    • Views: 3,762
    09-27-2009, 10:45 AM Go to last post
  50. Determining the probability that a sample is accurate

    I recently read an article concerning a new HIV vaccine developed in Thailand. The article can be found here...

    Started by Headbanger‎, 09-25-2009 02:40 PM
    • Replies: 1
    • Views: 3,437
    09-25-2009, 08:12 PM Go to last post
  51. Calculating sensitivity SS and specificity SP from the SS&SP of subitems

    Hello everyone, so here is a question for you. I have a table of 60 test items that were evaluated in both controls and patients, each item has %...

    Started by bergier‎, 09-21-2009 08:13 AM
    • Replies: 0
    • Views: 4,045
    09-21-2009, 08:13 AM Go to last post
  52. weighted standard error of the mean

    Hi, I am trying to calculate some statistical properties pertaining to mobility of cargo inside cells for my research, but due to my poor...

    Started by jvaughan5‎, 02-26-2008 01:49 PM
    • Replies: 1
    • Views: 13,984
    09-13-2009, 07:19 AM Go to last post
  53. Confidence Level of a Sorting Method?

    We recently had an issue in production. I had come up with a test method that seemed capable of sorting the bad product out from the good product....

    Started by ThaRide‎, 09-11-2009 03:10 PM
    • Replies: 0
    • Views: 3,596
    09-11-2009, 03:10 PM Go to last post
  54. GLM with binomial errors: underestimating interactions?

    I have problems with analyzing survival data, from experiments in a 2x2 factorial setting - the statistical approach which I am using seems to...

    Started by mango_man‎, 08-31-2009 06:13 PM
    • Replies: 3
    • Views: 3,793
    09-01-2009, 07:14 AM Go to last post
  55. Stepwise logistic regression (backwards LR)

    I have done a backwards LR stepwise logistic regression with a small data set of 22 cases and have a few questions. The full model had four...

    Started by dmausel‎, 08-26-2009 12:37 PM
    • Replies: 2
    • Views: 6,783
    08-27-2009, 03:37 PM Go to last post
  56. Exclamation Extreme right skewed data and repeated measures

    Hi! I’m writing for the first time and I would be grateful if someone could help me. I am total statistics beginner and additionally I’m a doctor so...

    Started by dr.iva‎, 08-21-2009 08:43 AM
    • Replies: 7
    • Views: 6,092
    08-22-2009, 07:44 PM Go to last post
  57. cumulative logit model

    Dear all, I would be very grateful if someone could help me! I used binary logistic model to draw a probability curve of areas having...

    Started by lucilan‎, 08-06-2009 07:03 AM
    • Replies: 5
    • Views: 5,197
    08-10-2009, 08:55 AM Go to last post
  58. Logistic regression model

    Hi all I was wondering if you were kind enough to give me a short advice on a statistical query i have. I have a sample of 15 children with...

    Started by kgeras‎, 08-09-2009 05:39 AM
    • Replies: 3
    • Views: 2,967
    08-09-2009, 05:35 PM Go to last post
  59. odds ratio in Fisher's exact test?

    Hi, I ran a fisher's exact test in SAS, in the output they show you the odds ratio and relative risk estimates. Can I use these estimates to...

    Started by jsoto‎, 07-31-2009 11:08 AM
    • Replies: 1
    • Views: 4,643
    08-01-2009, 10:18 AM Go to last post
  60. How to interpret hazard ratio for continuous variable

    Hi, I'm looking at survival curves for some data and wanting to see the effect of covariates in a Cox proportion hazards model, but am new to this...

    Started by pgseye‎, 07-09-2009 10:25 PM
    • Replies: 0
    • Views: 8,796
    07-09-2009, 10:25 PM Go to last post

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