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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Post What statistical test to use for species abundance between wet and dry season?

    Sorry if this question is trivial, I have a collection of camera trap data of recorded species during the rainy season and the dry season. I am...

    Started by BondHR‎, 01-07-2017 10:24 PM
    abundance, camera trap data, rstats, species data, statistics
    • Replies: 5
    • Views: 3,421
    01-08-2017, 02:38 PM Go to last post
  2. Temporal Distribution of Death

    Dear all, I plan to conduct a study. The preliminary aim is to examine the temporal distribution of death of terminal cancer patients in hospice...

    Started by bestmic‎, 12-20-2016 06:40 AM
    • Replies: 10
    • Views: 4,515
    01-03-2017, 04:40 AM Go to last post
  3. Add AUCs

    I want to add Area Under the Curve (AUC) from multiple meta analyses. AUC for each Meta analysis is given. How can I add them together?

    Started by Michael_svm‎, 12-20-2016 05:24 AM
    area under the curve, auc, diagnostic, roc
    • Replies: 6
    • Views: 4,249
    12-23-2016, 08:08 AM Go to last post
  4. Patterns in DNA, seperating signal from noise -- outliers?

    Hello all, I'm looking at patterns in fragments of RNA. What I need to do is separate the signals from noise in Exons (small regions of DNA/RNA)....

    Started by James1984‎, 10-10-2015 05:30 PM
    • Replies: 2
    • Views: 3,554
    12-22-2016, 05:05 AM Go to last post
  5. t-test or z-test for two proportions?

    We did an intervention to reduce the frequency of use of a certain type of treatment and now I want to compare the data pre vs post intervention. ...

    Started by hurricanemb‎, 12-18-2016 03:28 PM
    proportions, t-test, z-test
    • Replies: 3
    • Views: 3,901
    12-19-2016, 11:01 AM Go to last post
  6. Red face Interpreting Odds Ratios... weird question

    Hi, I sort of have a weird question. I have a basic understanding of ORs, and can interpret them, but it's never been clear to me why we...

    Started by Ceci18‎, 12-14-2016 10:34 AM
    • Replies: 6
    • Views: 3,619
    12-16-2016, 11:37 AM Go to last post
  7. Area under Kaplan Meier curve

    There is one thing bothering me for some time: What does area under Kaplan-Meier survival curve actally represent? Is there a plausible way to...

    Started by Markica85‎, 12-10-2016 05:55 AM
    kaplan meier, survival analysis
    • Replies: 0
    • Views: 3,681
    12-10-2016, 05:55 AM Go to last post
  8. Pooling time points to perform a Fisher test?

    Hello, I am currently trying to analyse an experiment to assess if rats with cerebral malformations have a sensitivity deficit on one of their...

    Started by Fanny-‎, 12-07-2016 12:10 PM
    anova, chi-square, fisher test
    • Replies: 4
    • Views: 3,972
    12-09-2016, 03:58 AM Go to last post
  9. What kind of statistical test can be used for my data?

    It is my first post on this forum so please be gentle. If it is not a proper section I would appreciate if moderator moves the thread to the correct...

    Started by Shaxi Liver‎, 12-07-2016 11:56 AM
    • Replies: 1
    • Views: 3,008
    12-07-2016, 01:27 PM Go to last post
  10. How to obtain an unbiased post-stratified estimator for survival probabilities?

    Suppose I have estimated the survival probabilities $\hat{S(t)}_1, \hat{S(t)}_2, \ldots, \hat{S(t)}_H$ from $H$ strata. Now I want to get an unbiased...

    Started by Blain Waan‎, 08-12-2016 08:14 PM
    estimator, stratification, survival
    • Replies: 3
    • Views: 3,828
    12-06-2016, 11:07 AM Go to last post
  11. Why not use Kaplan Meier?

    In the method described here http://dmkd.cs.vt.edu/papers/TKDE17.pdf R code implementation is provided ...

    Started by pablrodr‎, 12-02-2016 04:07 PM
    exponential distribution, kaplan meier, weibull distribution
    • Replies: 5
    • Views: 3,121
    12-03-2016, 09:56 AM Go to last post
  12. Bird Community Ecology - BACI experiment

    Greetings! I'm currently trying to investigate the impact of an event on the bird community of a National Park on my country. For that I have...

    Started by Fsmelo‎, 12-02-2016 10:36 AM
    baci, community ecology, ecology
    • Replies: 2
    • Views: 3,356
    12-02-2016, 03:19 PM Go to last post
  13. How to use chi-square test correspondence between features and response in R?

    There is a set of tumors,each one includes five features, which relate to one gene type result. Tumor Feature 1 ... Feature 5 Gene type 1 ...

    Started by l35633‎, 11-27-2016 12:56 PM
    chi-square, features, response
    • Replies: 0
    • Views: 3,222
    11-27-2016, 12:56 PM Go to last post
  14. MDS vs ANOVA / GLM methods - how and why?

    Hello to all :wave: I am a new member of this forum and the reason why I ended up here is the following: like many others, I am in desperate need of...

    Started by caralynne‎, 11-26-2016 06:17 AM
    • Replies: 0
    • Views: 3,206
    11-26-2016, 06:17 AM Go to last post
  15. How the estimate a smple size ?

    Hi everybody; I am a PhD student, my thesis focuses on the study of reproductive health among teenagers girls . For that, I'am going to work in...

    Started by siham‎, 11-24-2016 05:41 PM
    • Replies: 2
    • Views: 3,146
    11-25-2016, 12:15 PM Go to last post
  16. Help with linear model

    Hi guys, I'm really struggling with the relevant coding for this, I'm using Rstudio. I need a Linear model with Gaussian error structure to find...

    Started by imbricata‎, 11-07-2016 05:07 AM
    • Replies: 1
    • Views: 3,769
    11-23-2016, 10:51 AM Go to last post
  17. Model Selection in Survival Analysis

    I'm having trouble with parametric model selection in survival analysis. I founded this sequence of steps in some presentation. This is an...

    Started by askazy‎, 11-20-2016 02:53 PM
    • Replies: 1
    • Views: 3,541
    11-23-2016, 10:44 AM Go to last post
  18. estimating start point of a production of y" -ie findx for y=0 given y values for x>0

    I hope I can explain the problem clearly and its not an obvious solution. the application area is say an event (in the body) at say day=0 starts the...

    Started by azStats‎, 11-07-2016 09:47 AM
    • Replies: 3
    • Views: 4,125
    11-23-2016, 04:29 AM Go to last post
  19. Help with calculating probability?

    I have a strange set of data, it was counting the number of animals entering and leaving a shelter as a 'count' of how many were in the shelter. We...

    Started by zoologist‎, 11-22-2016 07:55 PM
    • Replies: 0
    • Views: 2,484
    11-22-2016, 07:55 PM Go to last post
  20. Exclamation Experimental design: Gender comparison in a novel memory matrix.

    Hello, I am a medical student who knows very little about biostats and would like some one to tell me whether my analysis for my research makes...

    Started by Syeda‎, 11-20-2016 06:13 AM
    • Replies: 4
    • Views: 3,232
    11-22-2016, 07:55 AM Go to last post
  21. Proportional hazards and Cox Model

    I'm trying to fit a Cox model, but there is some problems. I have the following variables in the model. - Group: 1, 2, ..., 9 - Sex: 1 female...

    Started by askazy‎, 11-09-2016 04:29 PM
    • Replies: 5
    • Views: 3,444
    11-10-2016, 12:42 PM Go to last post
  22. Cumulative Incidence with Confidence Intervals when using IPTW

    Dear Stata users, I'm doing a time to event analysis with inverse probability of treatment weights(IPTW) estimated with propensity scores from a...

    Started by Soren‎, 11-10-2016 10:41 AM
    cumulative incidence, iptw, propensity scores
    • Replies: 2
    • Views: 3,668
    11-10-2016, 12:01 PM Go to last post
  23. Help with setting my study!

    Hi all, I'm a newbie to biostatistics and I'm trying to figure out how to set the statistical part of my final project. I'm a dentistry student and...

    Started by Deepchamfer‎, 11-08-2016 09:14 AM
    • Replies: 1
    • Views: 2,702
    11-08-2016, 09:16 AM Go to last post
  24. Parallel and subsequential diagnostic tests

    Hey guys, i just ran into a problem: I am having two predictive models: Model 1: Sensitivity: 0.8 Specificity: 0.4

    Started by lilchaos‎, 11-02-2016 09:25 AM
    • Replies: 12
    • Views: 3,942
    11-08-2016, 02:59 AM Go to last post
  25. Dataset for statistical analysis

    Dear all, I work in Rome for the Italian National Health Service (www.iss.it); I am currently working on a European clinic project called EMTICS...

    Started by mtallon‎, 10-17-2016 02:09 PM
    • Replies: 4
    • Views: 4,729
    11-07-2016, 04:55 AM Go to last post
  26. Please help me select the correct statistical test

    I'm a general surgery resident and am conducting a quality improvement study about waste in the OR. My statistics background is limited to what I was...

    Started by billingsmd‎, 11-06-2016 05:59 PM
    • Replies: 5
    • Views: 3,674
    11-07-2016, 02:08 AM Go to last post
  27. Medical news story - Is this an OK way to report the stats?

    I'm a medical writer covering an upcoming research paper. I'm new to the forum, so please LMK if this is not an appropriate place for my question. ...

    Started by tobmed‎, 11-04-2016 08:49 AM
    • Replies: 2
    • Views: 3,715
    11-04-2016, 12:40 PM Go to last post
  28. Observed difference between two test for same patient is due to chance?

    Hi, I have results from two very sensitive but different lab test trying to find pathogen in a patient sample. For some patients results from two...

    Started by deepbiomed‎, 11-02-2016 01:02 PM
    • Replies: 0
    • Views: 2,511
    11-02-2016, 01:02 PM Go to last post
  29. likelihood ratio test and AIC

    Can somebody please help me answer the question in the attachment. I have a test next week. please help

    Started by Jeff Hardy‎, 10-31-2016 11:47 AM
    • Replies: 5
    • Views: 3,532
    11-02-2016, 11:40 AM Go to last post
  30. Help with correct model formula for a repeated measures design

    Hi there, I will really appreciate some help denoting the proper formula to fit a GLM for the following repeated measures data: I investigated...

    Started by phmontoya‎, 11-01-2016 10:45 AM
    • Replies: 0
    • Views: 2,211
    11-01-2016, 10:45 AM Go to last post
  31. Question about sample size penalty for looking at data mid-trial

    Hi, we're running a clinical trial for a skin treatment with a medical device that has a strong effect. We are using an inter-patient control (no...

    Started by bma449‎, 10-24-2016 04:58 PM
    interim analysis
    • Replies: 3
    • Views: 4,400
    10-29-2016, 01:08 PM Go to last post
  32. Help with regards to deciding appropriate statistical test for success criteria

    Hello, I have the collective data of 35 eyes that underwent trabeculectomy surgery for glaucoma control. There is no control group, and...

    Started by neosage‎, 10-27-2016 01:27 PM
    • Replies: 1
    • Views: 2,772
    10-27-2016, 05:00 PM Go to last post
  33. Converting GEE and MIXED from SAS to SPSS

    Hello, Im trying to do data analysis with GEE and/or Mixed models but get stuck in choosing the right SPSS syntax. I have data from subjects...

    Started by hoipiepeloi‎, 10-25-2016 04:37 PM
    gee mixed
    • Replies: 0
    • Views: 2,901
    10-25-2016, 04:37 PM Go to last post
  34. Help for sample size calculation

    in my prospective cohort study I will assess the serum level of a vitamin in a group of patients the normal reference serum range is 10-30 in normal...

    Started by emmyomran‎, 10-22-2016 12:04 PM
    sample size, sample size calculation
    • Replies: 1
    • Views: 3,303
    10-23-2016, 11:37 AM Go to last post
  35. Correlated variables in Cox model - which one is best

    Hi there, I am building a Cox model. I have two variables that are different measures of the same thing and they are therefore correlated with each...

    Started by dhmallon‎, 10-23-2016 09:27 AM
    cox proportional hazards, survival, variable selection
    • Replies: 0
    • Views: 2,697
    10-23-2016, 09:27 AM Go to last post
  36. HELP with data collection methods and data analysis in quantitative research : )

    I am doing a research proposal on the effect of a drug on haemorrhage growth in traumatic brain injury. My null hypothesis: TXA does not reduce the...

    Started by murrayk‎, 10-21-2016 09:11 PM
    • Replies: 1
    • Views: 2,800
    10-22-2016, 12:53 AM Go to last post
  37. Appropriate statistical test for HR's comparison between 2 population

    In case of 2 population, the first has HR X for the study's outcome (between the exposed and non-exposed groups), and the second has HR of Y (between...

    Started by ronitrot‎, 10-20-2016 09:03 AM
    • Replies: 1
    • Views: 3,114
    10-21-2016, 06:02 AM Go to last post
  38. Which statistical test to use for my data analysis

    Hi everyone, Could someone help me to know which statistics should i use for my data analysis. I did my project on "personal exposure...

    Started by Biosapien‎, 10-15-2016 01:52 PM
    • Replies: 4
    • Views: 2,872
    10-19-2016, 05:39 AM Go to last post
  39. Recurrent Event Survival Analysis

    Hi there, I'm working on a research on individuals who enter financial distress using the Cox proportional hazards model. In this case the...

    Started by Mkkl‎, 10-17-2016 07:46 AM
    cox proportional hazard, recurrent events, survival analysis
    • Replies: 0
    • Views: 2,506
    10-17-2016, 07:46 AM Go to last post
  40. Sample Size Calculation (HELP!)

    Hi all, I wish someone could help me out. I am trying to estimate the sample size for a national health survey. From the previous report,...

    Started by chummsy‎, 10-12-2016 08:30 PM
    • Replies: 1
    • Views: 2,770
    10-14-2016, 05:22 AM Go to last post
  41. Best Method for Comparison of Bacterial Community Compositions

    Hi! I have curated 454 pyrosequencing data using Mothur. I have clustered reads from each sample into OTUs at a unique level. (Please see attached...

    Started by samche42‎, 10-06-2016 09:17 AM
    • Replies: 0
    • Views: 2,960
    10-06-2016, 09:17 AM Go to last post
  42. Markov Process to estimate time until death

    Are there any websites that show examples of data setup and SAS code using some sort of Markov model to estimate time until or probability of death?...

    Started by lancearmstrong1313‎, 10-05-2016 12:14 PM
    • Replies: 0
    • Views: 2,832
    10-05-2016, 12:14 PM Go to last post
  43. Which comparison of means test to use?

    I've got myself confused about which test to use. I have done a cross sectional survey exploring the difference between pain as measured with a...

    Started by jackdog3‎, 10-04-2016 06:06 AM
    • Replies: 1
    • Views: 2,480
    10-04-2016, 11:14 AM Go to last post
  44. comparing sensitivity, specificity, and PPV of different cohorts-is it possible?

    hello and thanks in advance for helping out! i hope that my questions will not be terribly on-profesional .. i'm trying to figure how to compare...

    Started by mrnogi‎, 10-03-2016 03:57 PM
    • Replies: 2
    • Views: 2,972
    10-03-2016, 11:24 PM Go to last post
  45. Poll: How do you handle subjects having very different patterns?

    Good day everyone - I am curious as to what you all do in these situations. If you are running a sleep study, and you are simply using two...

    Started by allie_moore‎, 09-26-2016 11:35 AM
    • Replies: 2
    • Views: 3,569
    09-26-2016, 12:14 PM Go to last post
  46. Estimating main effects in a two factorial log linear model when applied to RNA-seq

    Hi everybody, I'm going to apply multiDE, an R package for detection of DEG in multiple treatment conditions, on some RNA-seq time series data......

    Started by Fate.gh‎, 09-16-2016 02:29 PM
    log-linear, rna-seq
    • Replies: 0
    • Views: 2,670
    09-16-2016, 02:29 PM Go to last post
  47. Survival analysis

    Hi there, I am doing some breast cancer survival analysis on population-based registry data...I have outlined to estimate incidence trends and...

    Started by MAYA85‎, 09-15-2016 02:28 PM
    • Replies: 2
    • Views: 3,519
    09-16-2016, 04:20 AM Go to last post
  48. What test to use?

    Hi all, I am new to statistics. Now, I am doing a research but I don't know which test to use. Basically, I have four groups with both positive...

    Started by Upupgo‎, 09-14-2016 01:50 PM
    • Replies: 1
    • Views: 2,713
    09-14-2016, 02:54 PM Go to last post
  49. Question R caret package: problems understanding the functions in confusionMatrix

    Hey, I earlier posted about the problematic interpretation of PPV (positive predictive value). As there seems to be no easy solution for that I...

    Started by lilchaos‎, 09-02-2016 08:17 AM
    • Replies: 2
    • Views: 3,244
    09-13-2016, 01:44 AM Go to last post
  50. Talking Analysing pre- and post-treatment lactate curves

    Good morning all, Has anyone got experience with analysing lactate against power curves? I have pre- and post-treatment lactate curves for 10...

    Started by WildlifeStats‎, 09-12-2016 03:21 AM
    curve, curves
    • Replies: 0
    • Views: 2,633
    09-12-2016, 03:21 AM Go to last post
  51. [SPSS - post hoc analysis and Logistic regression] When the result don't line up

    I'm a medical student doing his research interneship. We're currently investigating if there's a link between motoric and mental outcome and MRI...

    Started by j0hnj0hn‎, 09-08-2016 05:34 AM
    fisher exact test, logistic regression, medicine, post hoc tests
    • Replies: 0
    • Views: 3,053
    09-08-2016, 05:34 AM Go to last post
  52. How to evaluate significance.

    Hi, I have 58 samples and an enrichment analysis was done to each of them. So for each sample I have a list of enriched terms. I've collected the...

    Started by MinieMe‎, 09-06-2016 11:14 AM
    • Replies: 0
    • Views: 2,457
    09-06-2016, 11:14 AM Go to last post
  53. ROC curve cutoff not significant, but it works

    I'm dealing with a numerical variable and its prognostic significance in a sample of cancer patients. I'm trying to find an optimal cutoff point for...

    Started by Markica85‎, 09-04-2016 07:05 AM
    • Replies: 4
    • Views: 3,188
    09-04-2016, 01:14 PM Go to last post
  54. How to analyze this data

    Hello, I need guidance in analyzing the outcome. I have 4 independent variables, and 2 dependent variables. The sample size is ~600. I...

    Started by reddy‎, 09-01-2016 03:22 PM
    statistical methods
    • Replies: 1
    • Views: 2,283
    09-02-2016, 03:46 AM Go to last post
  55. Help deciding paired vs unpaired t-test

    Hi, I am analyzing an experiment in which protein levels were examined in two different strains of bacteria. Lets call them A and B. Three...

    Started by abbey‎, 09-01-2016 01:37 PM
    comparison, t-test
    • Replies: 2
    • Views: 2,487
    09-01-2016, 02:19 PM Go to last post
  56. Help decide on appropriate test for experiment design

    Hello - new to the forums here! I work in cell biology and a colleague and I are designing an experiment to determine the appropriate...

    Started by Dan Kordella‎, 08-11-2016 01:04 PM
    • Replies: 5
    • Views: 3,007
    08-30-2016, 04:01 PM Go to last post
  57. Positive predictive value of biased data

    Hey, I am currently dealing with prediction of binary data due to structural alerts. This means if a substructure is within the query structure it...

    Started by lilchaos‎, 08-29-2016 03:03 AM
    • Replies: 2
    • Views: 2,415
    08-30-2016, 01:21 AM Go to last post
  58. Matched Groups Statistics

    Hello all hope this is the right thread for the question and that someone will be able to help me out :confused: I have created a propensity...

    Started by summit cross‎, 08-29-2016 03:21 AM
    matched, matched controls, propensity score matching, regression analysis
    • Replies: 2
    • Views: 3,073
    08-29-2016, 01:42 PM Go to last post
  59. I need advice on Fisher's exact test

    I recently submitted a paper and in my study, I wanted to see if there is an association between a gene mutation and the absence/presence of the...

    Started by Coral‎, 08-25-2016 03:58 AM
    • Replies: 4
    • Views: 3,305
    08-29-2016, 03:50 AM Go to last post
  60. calculate p value significance

    How to calculate p value significance for the following? We educated 334 individuals over the age of 50 about cancer. 87 (26.05%) of them made...

    Started by deepbiomed‎, 08-26-2016 11:24 AM
    #cancer #education effect
    • Replies: 2
    • Views: 2,669
    08-27-2016, 06:48 AM Go to last post

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