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# Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

1. ### Odds ratio and p-value

could anyone plz help me out.... PRESCENCE OF INURY TO OCULAR ADNEXAE YES NO MILD 70 12 MODERATE ...

• Replies: 10
• Views: 2,641
09-04-2015, 08:48 PM
2. ### Test for linear trend in odds ratio in linear regression

I often see epidemiological studies where a continuous variable has been divided into quantiles and the odds ratios for each quantile compared with a...

• Replies: 10
• Views: 11,666
09-04-2015, 01:16 PM
3. ### Age-adjusting survey data to compare weighted estimates from multiple surveys?

Hello, I am looking to compare weighted estimates (counts and proportions) of people with disabilities from the National Health Interview Survey,...

• Replies: 0
• Views: 1,774
09-03-2015, 01:36 PM
4. ### Multivariate Analysis for a paired subject longitudinal microbiome study

I am trying to finish my stats analyses for a microbiome study, and the last thing on my list is multivariate analysis. I have a paired group of...

• Replies: 0
• Views: 801
09-03-2015, 09:55 AM
5. ### analysis for sparse contingency table

I am analyzing a 2x2x3x2 contingency table. The covariates are treatment (2 different kinds, TR1 and TR2, both binary), location of treatment (3...

• Replies: 2
• Views: 1,957
08-31-2015, 09:12 PM
6. ### Risk Ratio and Confidence Intervals...

Hello, I would be hugely grateful if someone could help shed some light?! As I understand it, Risk Ratio (RR) of <1 indicates under prediction, 1...

• Replies: 8
• Views: 1,921
08-28-2015, 05:15 AM
7. ### [R]: Mixed model for non-normal y with many 0s and some high values in nested design

Dear all, I am currently writing my master thesis on the effect of a certain insecticide on bumble bee colonies. In particular I am testing...

• Replies: 9
• Views: 2,902
08-28-2015, 04:45 AM
8. ### repeated measure with some people quit in mid-way

Got answered from a SPSS forum.

• Replies: 1
• Views: 1,707
08-27-2015, 04:07 PM
9. ### How should I connect alleles?

I am new at statistics and I have problem that I have no idea how to solve. I have biological data, which includes expression levels (130...

• Replies: 2
• Views: 990
08-27-2015, 12:36 PM
10. ### Basic Sample Size Question

hello this is my first thread, i want to ask something, example: i want to to know the association between cholesterol level (categorized as extreme...

• Replies: 3
• Views: 1,559
08-27-2015, 09:23 AM
11. ### Frequent ED attenders - statistical test

Hi I've a problem at work and looking for some suggestions as to how to progress. We took a sample of 100 patients. For each patient we...

• Replies: 11
• Views: 2,288
08-27-2015, 08:30 AM
12. ### imputations

Dear all: I am working with data from a large cohort study in which participants were asked, retrospectively, about their work history. Data are...

• Replies: 0
• Views: 1,430
08-23-2015, 04:59 PM
13. ### Is a two-way anova enough?

Hello everyone. As I am far away from being an expert in biostatistics and get confused by it easily (I will do some training in the next year and...

• Replies: 0
• Views: 1,246
08-19-2015, 06:24 AM
14. ### Is independent t-test still justified?

Hello! I am kinda stuck and undecided whether I can use the independent samples t-test in a specific case I'm about to describe, so I'm hoping for...

• Replies: 3
• Views: 1,678
08-18-2015, 07:14 AM
15. ### Categorical predictor

Hi all I have one question concerning the presentation of results from a regression model. If you have a predictor with more than 2 categories...

• Replies: 3
• Views: 1,877
08-16-2015, 10:16 AM
16. ### Case Based Learning

Hi - I teach a case-based class in Biostatistics at a small liberal arts college and am looking for good (or bad!) examples of primary literature...

• Replies: 0
• Views: 1,397
08-14-2015, 03:31 PM
17. ### Unsure of correct model

I have limited background in ecological statistics. I have pages of raw data at my disposal including quadrat/transect counts, abundances etc....

• Replies: 0
• Views: 1,348
08-13-2015, 08:50 AM
18. ### CIF with 95% confidence interval STATA 13

I wanted to ask you for help on how to draw the CIF curve after a competing risk analysis in STATA 13, along with the 95% confidence interval on the...

• Replies: 0
• Views: 928
08-12-2015, 04:40 PM
19. ### few replicates with several categories and subgroups

- deleted (not pressing anymore) -

• Replies: 0
• Views: 1,274
08-10-2015, 04:01 AM
20. ### Significant interaction

Dear all How do you present the results in a publication if you have a significant interaction term in a regression model. In my model I have a...

• Replies: 1
• Views: 1,717
08-06-2015, 04:22 PM
21. ### Conditional logistic regression, multiple testing.

Hi everyone! I have 10 exposure variables that i would like to analyze univariate. I've applied the conditional logistic regression model to each...

• Replies: 8
• Views: 1,315
08-06-2015, 01:53 PM
22. ### Paired T-Test and/or repeated measures ANOVA/mixed ANOVA -please help!

Hey everyone, I've been trying to confirm this for a while but I haven't been able to find a conclusive answer. I'm guessing the answer is pretty...

• Replies: 3
• Views: 872
08-05-2015, 05:46 AM
23. ### Change from baseline in proportion

Dear all Can anyone give me some advice for the following problem: I'm analyzing a binary outcome (patients being able to perform a specific task...

• Replies: 4
• Views: 1,423
08-04-2015, 03:46 PM
24. ### help to decide statistic approach

Hi, I am a newbie in statistics and many thanks in advance. My experiment involves three subjects and two types of treatments (A, B). Because the...

• Replies: 0
• Views: 663
08-04-2015, 08:29 AM
25. ### Several concerns about Cox regression analysis models

Hi, I'm working a retrospective / prospective cohort study on a very rare disease (5 patients a year presenting in my institution). I have a...

• Replies: 8
• Views: 2,272
07-31-2015, 10:18 AM
26. ### ROC analysis using survival data

Dear readers, I would like to create two groups of patients depending on value of numerical parameter (like age), i.e. younger and older than 60...

• Replies: 1
• Views: 3,535
07-31-2015, 10:07 AM
27. ### How to correctly combine two binary variables into one dependent variable?

I want to create a combined death or stroke rate binary variable. For each row (patient data), I have data for death and stroke (yes/no)...

• Replies: 0
• Views: 747
07-31-2015, 09:19 AM
28. ### Which test should I apply?

Hi, I have a set of of things (SNPs) which explain a percentage of variance of a trait. I got a subset of those SNPs and they explain a higher...

• Replies: 1
• Views: 885
07-30-2015, 11:37 AM
29. ### Pearsons Correlation, Two-way ANOVA, Linear Regression Test, Chi-Square Test or None

During research, you have asked your participants whether or not they have ever experienced financial difficulties (yes or no). You have three...

• Replies: 1
• Views: 1,241
07-29-2015, 02:48 PM
30. ### Variable selection with longitudinal and correlated data

Hi, I'm working with a high-dimensional medical database, with detailed monthly medication reimbursement data as well as occurence of diverse...

• Replies: 2
• Views: 1,288
07-28-2015, 03:09 AM
31. ### Multiple group stats - Protein Work - Anova or T-test

Hi Everyone, I have a question that I'm stuck on. I think I know the correct way to do it but from what I see when I visually graph I don't believe...

• Replies: 0
• Views: 1,509
07-27-2015, 04:21 PM
32. ### Interpretation of Mantel-Haenszel Statistics

We have conducted an experiment with 2 groups and a dichotomous outcome on 3 occasions and for each occasion we have a 2x2 contingency table. Rather...

• Replies: 0
• Views: 1,357
07-25-2015, 10:36 AM
33. ### The Future of Clinical Trials Biostatistics - Bayesian?

I have noticed a trend with hiring managers to vault candidates that are well versed in Bayesian analysis to the top. This is not necessarily...

• Replies: 1
• Views: 890
07-22-2015, 09:14 PM
34. ### How to analyze proportions from large datasets

Hello all! This question will likely reveal my lack of basic statistics knowledge, but I can't seem to find the answer in textbooks or on this forum....

• Replies: 1
• Views: 1,018
07-20-2015, 02:23 AM
35. ### how to interpret or report the result

i have done a project looking at how many malpositioned nasogastric tubes were detected on doing chest radiography in patients in ICU. can i report...

• Replies: 1
• Views: 1,400
07-17-2015, 07:43 AM
36. ### General Linear Model using proportions as raw data - transformation needed?

Hi, I have become confused in my reading of analysis of proportions. I was all set to analyse my data using a general linear model after...

• Replies: 0
• Views: 1,245
07-16-2015, 11:12 PM
37. ### Request for help or orientation

Hello. I am new here and I admit I suck at statistics. I need your help on how to solve a statistical problem. Please don't give the easy answers...

• Replies: 1
• Views: 922
07-16-2015, 05:46 PM
38. ### Request for help on choosing a statistical test to determine the efficacy of a drug

Hi, I'm an undergraduate working on a project concerning peptides. I have data for a group of 12 peptides that were tested against 4 types of...

• Replies: 0
• Views: 1,294
07-16-2015, 09:06 AM
39. ### Treating Dependent Variable (Ordinal 5 item likert scale variable)

Hi all, I had a dependent variable of fatigue score in 4 cycles and i need to test with one Independent categorical variable which had 2...

• Replies: 2
• Views: 2,355
07-15-2015, 04:39 AM
40. ### Another "which tests to use?" question

Hi all, longtime lurker, first-time poster here. Reading people's questions and answers here really helped my understanding back when I was taking...

• Replies: 0
• Views: 1,192
07-11-2015, 12:17 PM
41. ### Request for advice on what statistical test to use for research on decision times

Basically the research we are doing involves measuring the time taken for two dolphin subjects to make their decision in a Matching-to-Sample study....

• Replies: 5
• Views: 1,777
07-11-2015, 02:41 AM
42. ### Study on prevalence of disease

Greetings! Can someone advise me on what is the appropriate name for the retrospective study of prevalence of certain disease within patients...

• Replies: 2
• Views: 1,188
07-08-2015, 01:56 PM
43. ### Clinical trial - stratified randomization

Hi all, There is something very basic I don't get about stratified randomization and I was hoping you might be willing to help me with. Say I have...

• Replies: 2
• Views: 1,576
07-02-2015, 11:54 AM
44. ### How do I chose between sensitivity/specificity and PPV/NPV?

I have just finished a validation study, where two specialists used the available information to classify patients according to their diseases status...

• Replies: 4
• Views: 2,416
07-02-2015, 03:01 AM
45. ### Incongruity between t-test and 2x2 repeated measures ANOVA/gain scores t-test/ANCOVA

Hi, it's the first time I post here. Forgive me if my English is not always correct. I want to ask about an incongruity I found when analyzing data...

• Replies: 4
• Views: 1,455
07-01-2015, 11:44 AM
46. ### Power analysis for Cox PH model

Hello, I am new here but have searched the forum before posting. I am planning a retrospective review of previously collected data. N=480. ...

• Replies: 1
• Views: 1,952
06-29-2015, 02:02 PM
47. ### sutiable study design?

Hi everyone. I would be thankful for any helpful advice regarding a suitable study design for a planned research. I have a series of approx. 100...

• Replies: 0
• Views: 1,210
06-25-2015, 01:10 PM
48. ### Cluster analysis when two domains measure the same thing

Hi all, first of all thank you for your help in advance. I have the following problem: I would like to perform a cluster analysis on my sample...

• Replies: 0
• Views: 882
06-25-2015, 09:48 AM
49. ### Unit of Analysis

Hi! Trying to determine which analysis is appropriate. Let me explain: -We have access to a community hospital records on the patient level....

• Replies: 0
• Views: 1,115
06-24-2015, 02:00 PM
50. ### Rate ratio interpretation for large estimates

Hi all, Just a quick question - I have many rate ratios and the 95% CIs, most of which have narrow CIs and reasonable RRs (e.g., 1.23). I've been...

• Replies: 6
• Views: 1,293
06-23-2015, 06:11 PM
51. ### how does stata calculate confidence intervals for age standardised means/proportions

Dear Stat Talkers! I'm using the following Stata command (see help mean): mean x, std(a) stdw(b) over(c) to get age-standardised mean or...

• Replies: 0
• Views: 758
Amu
06-23-2015, 01:35 PM
52. ### Identification of study design

Hi all, I'm just trying to figure out what to call the study design for the way my research has been set up, so could use some help! I have...

• Replies: 2
• Views: 2,485
06-21-2015, 10:09 PM
53. ### What will be the best test to determine the significance in my study?

The project does not have a simple design. It is planned as follows: 1. It is a longitudinal observation during 120 days in 48 subjects (with...

• Replies: 0
• Views: 1,025
06-19-2015, 06:16 AM
54. ### Conflicting Results Evaluating Proportional Hazards Assumption

Hello, Currently working on a survival analysis of some lung cancer patients. I am building a Cox PH model and was working on validating the PH...

• Replies: 0
• Views: 982
06-18-2015, 02:10 PM
55. ### Randomized trial with repeated measure - which test?

Hi, I´m currently conducting a randomized placebo trial where we test the effect of one treatment on a single outcome variable. We measure the...

• Replies: 3
• Views: 1,652
06-17-2015, 07:15 AM
56. ### PAF through formula or through Conditional Logistic Regression

Hi all, In a large registry dataset of psychiatric patients, if one wants to find the excess risk of schizophrenia patients developing depression,...

• Replies: 2
• Views: 1,711
06-17-2015, 05:38 AM

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