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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Odds ratio and p-value

    could anyone plz help me out.... PRESCENCE OF INURY TO OCULAR ADNEXAE YES NO MILD 70 12 MODERATE ...

    Started by jacob‎, 09-04-2015 11:05 AM
    • Replies: 10
    • Views: 2,641
    09-04-2015, 08:48 PM Go to last post
  2. Test for linear trend in odds ratio in linear regression

    I often see epidemiological studies where a continuous variable has been divided into quantiles and the odds ratios for each quantile compared with a...

    Started by Disvengeance‎, 07-13-2014 09:50 AM
    • Replies: 10
    • Views: 11,666
    09-04-2015, 01:16 PM Go to last post
  3. Age-adjusting survey data to compare weighted estimates from multiple surveys?

    Hello, I am looking to compare weighted estimates (counts and proportions) of people with disabilities from the National Health Interview Survey,...

    Started by GrumpyEpiGuy‎, 09-03-2015 01:36 PM
    • Replies: 0
    • Views: 1,774
    09-03-2015, 01:36 PM Go to last post
  4. Multivariate Analysis for a paired subject longitudinal microbiome study

    I am trying to finish my stats analyses for a microbiome study, and the last thing on my list is multivariate analysis. I have a paired group of...

    Started by Gilthoniel‎, 09-03-2015 09:55 AM
    longitudinal study, microbiome, multivariate analysis, paired sample
    • Replies: 0
    • Views: 801
    09-03-2015, 09:55 AM Go to last post
  5. analysis for sparse contingency table

    I am analyzing a 2x2x3x2 contingency table. The covariates are treatment (2 different kinds, TR1 and TR2, both binary), location of treatment (3...

    Started by jpluta26‎, 08-31-2015 01:58 PM
    categorical data analysis, contingency table, log-linear, sparse
    • Replies: 2
    • Views: 1,957
    08-31-2015, 09:12 PM Go to last post
  6. Risk Ratio and Confidence Intervals...

    Hello, I would be hugely grateful if someone could help shed some light?! As I understand it, Risk Ratio (RR) of <1 indicates under prediction, 1...

    Started by datacrunch‎, 08-19-2015 01:31 PM
    • Replies: 8
    • Views: 1,921
    08-28-2015, 05:15 AM Go to last post
  7. [R]: Mixed model for non-normal y with many 0s and some high values in nested design

    Dear all, I am currently writing my master thesis on the effect of a certain insecticide on bumble bee colonies. In particular I am testing...

    Started by master student‎, 08-05-2015 04:32 AM
    anova, mixed model, nesting, zero inflated, zeros
    • Replies: 9
    • Views: 2,902
    08-28-2015, 04:45 AM Go to last post
  8. repeated measure with some people quit in mid-way

    Got answered from a SPSS forum.

    Started by fengyuwuzu‎, 08-27-2015 03:24 PM
    • Replies: 1
    • Views: 1,707
    08-27-2015, 04:07 PM Go to last post
  9. How should I connect alleles?

    I am new at statistics and I have problem that I have no idea how to solve. I have biological data, which includes expression levels (130...

    Started by ASzy‎, 08-27-2015 10:23 AM
    alleles, biostatistics, small data set
    • Replies: 2
    • Views: 990
    08-27-2015, 12:36 PM Go to last post
  10. Basic Sample Size Question

    hello this is my first thread, i want to ask something, example: i want to to know the association between cholesterol level (categorized as extreme...

    Started by Denxe‎, 08-27-2015 09:02 AM
    • Replies: 3
    • Views: 1,559
    08-27-2015, 09:23 AM Go to last post
  11. Frequent ED attenders - statistical test

    Hi I've a problem at work and looking for some suggestions as to how to progress. We took a sample of 100 patients. For each patient we...

    Started by scotchpie‎, 08-26-2015 05:16 AM
    • Replies: 11
    • Views: 2,288
    08-27-2015, 08:30 AM Go to last post
  12. imputations

    Dear all: I am working with data from a large cohort study in which participants were asked, retrospectively, about their work history. Data are...

    Started by sonia zam‎, 08-23-2015 04:59 PM
    • Replies: 0
    • Views: 1,430
    08-23-2015, 04:59 PM Go to last post
  13. Is a two-way anova enough?

    Hello everyone. As I am far away from being an expert in biostatistics and get confused by it easily (I will do some training in the next year and...

    Started by Makenshi‎, 08-19-2015 06:24 AM
    • Replies: 0
    • Views: 1,246
    08-19-2015, 06:24 AM Go to last post
  14. Is independent t-test still justified?

    Hello! I am kinda stuck and undecided whether I can use the independent samples t-test in a specific case I'm about to describe, so I'm hoping for...

    Started by stabilos‎, 08-18-2015 04:43 AM
    • Replies: 3
    • Views: 1,678
    08-18-2015, 07:14 AM Go to last post
  15. Categorical predictor

    Hi all I have one question concerning the presentation of results from a regression model. If you have a predictor with more than 2 categories...

    Started by sternchen‎, 08-11-2015 12:59 PM
    • Replies: 3
    • Views: 1,877
    08-16-2015, 10:16 AM Go to last post
  16. Case Based Learning

    Hi - I teach a case-based class in Biostatistics at a small liberal arts college and am looking for good (or bad!) examples of primary literature...

    Started by BiostatsProf‎, 08-14-2015 03:31 PM
    • Replies: 0
    • Views: 1,397
    08-14-2015, 03:31 PM Go to last post
  17. Unsure of correct model

    I have limited background in ecological statistics. I have pages of raw data at my disposal including quadrat/transect counts, abundances etc....

    Started by dingo173‎, 08-13-2015 08:50 AM
    • Replies: 0
    • Views: 1,348
    08-13-2015, 08:50 AM Go to last post
  18. CIF with 95% confidence interval STATA 13

    I wanted to ask you for help on how to draw the CIF curve after a competing risk analysis in STATA 13, along with the 95% confidence interval on the...

    Started by eabuassi‎, 08-12-2015 04:40 PM
    • Replies: 0
    • Views: 928
    08-12-2015, 04:40 PM Go to last post
  19. few replicates with several categories and subgroups

    - deleted (not pressing anymore) -

    Started by nalu‎, 08-10-2015 04:01 AM
    • Replies: 0
    • Views: 1,274
    08-10-2015, 04:01 AM Go to last post
  20. GEE model with Error " The generalized Hessian matrix is not positive definite"

    Hi experts, When I was trying to build a marginal GEE model (logit = bin) for a censoring variable in a survival study, I implemented the following...

    Started by freezingswallow‎, 08-08-2015 01:44 PM
    • Replies: 1
    • Views: 5,968
    08-08-2015, 07:01 PM Go to last post
  21. Significant interaction

    Dear all How do you present the results in a publication if you have a significant interaction term in a regression model. In my model I have a...

    Started by sternchen‎, 08-06-2015 04:08 PM
    • Replies: 1
    • Views: 1,717
    08-06-2015, 04:22 PM Go to last post
  22. Conditional logistic regression, multiple testing.

    Hi everyone! I have 10 exposure variables that i would like to analyze univariate. I've applied the conditional logistic regression model to each...

    Started by Nisse‎, 08-05-2015 03:16 PM
    logisitic regression, logistic regression stata, multiple testing, strata
    • Replies: 8
    • Views: 1,315
    08-06-2015, 01:53 PM Go to last post
  23. Paired T-Test and/or repeated measures ANOVA/mixed ANOVA -please help!

    Hey everyone, I've been trying to confirm this for a while but I haven't been able to find a conclusive answer. I'm guessing the answer is pretty...

    Started by lmac366‎, 08-05-2015 01:32 AM
    help me, mixed anova, paired t-test, repeated measure anova
    • Replies: 3
    • Views: 872
    08-05-2015, 05:46 AM Go to last post
  24. Change from baseline in proportion

    Dear all Can anyone give me some advice for the following problem: I'm analyzing a binary outcome (patients being able to perform a specific task...

    Started by sternchen‎, 08-04-2015 12:13 PM
    • Replies: 4
    • Views: 1,423
    08-04-2015, 03:46 PM Go to last post
  25. help to decide statistic approach

    Hi, I am a newbie in statistics and many thanks in advance. My experiment involves three subjects and two types of treatments (A, B). Because the...

    Started by lmuri‎, 08-04-2015 08:29 AM
    • Replies: 0
    • Views: 663
    08-04-2015, 08:29 AM Go to last post
  26. Several concerns about Cox regression analysis models

    Hi, I'm working a retrospective / prospective cohort study on a very rare disease (5 patients a year presenting in my institution). I have a...

    Started by Markica85‎, 07-16-2015 09:18 AM
    • Replies: 8
    • Views: 2,272
    07-31-2015, 10:18 AM Go to last post
  27. ROC analysis using survival data

    Dear readers, I would like to create two groups of patients depending on value of numerical parameter (like age), i.e. younger and older than 60...

    Started by Markica85‎, 07-31-2015 09:44 AM
    • Replies: 1
    • Views: 3,535
    07-31-2015, 10:07 AM Go to last post
  28. Question How to correctly combine two binary variables into one dependent variable?

    I want to create a combined death or stroke rate binary variable. For each row (patient data), I have data for death and stroke (yes/no)...

    Started by hongh‎, 07-31-2015 09:19 AM
    binary dependent variable, combine variables
    • Replies: 0
    • Views: 747
    07-31-2015, 09:19 AM Go to last post
  29. Which test should I apply?

    Hi, I have a set of of things (SNPs) which explain a percentage of variance of a trait. I got a subset of those SNPs and they explain a higher...

    Started by AleixArnau‎, 07-30-2015 10:21 AM
    test question
    • Replies: 1
    • Views: 885
    07-30-2015, 11:37 AM Go to last post
  30. Pearsons Correlation, Two-way ANOVA, Linear Regression Test, Chi-Square Test or None

    During research, you have asked your participants whether or not they have ever experienced financial difficulties (yes or no). You have three...

    Started by robertshane‎, 07-29-2015 02:35 PM
    biostats, chi square test, linear regression, pearson correlation, two way anova
    • Replies: 1
    • Views: 1,241
    07-29-2015, 02:48 PM Go to last post
  31. Variable selection with longitudinal and correlated data

    Hi, I'm working with a high-dimensional medical database, with detailed monthly medication reimbursement data as well as occurence of diverse...

    Started by yohannM‎, 07-27-2015 09:31 AM
    correlated, longitudinal, penalized regression
    • Replies: 2
    • Views: 1,288
    07-28-2015, 03:09 AM Go to last post
  32. Multiple group stats - Protein Work - Anova or T-test

    Hi Everyone, I have a question that I'm stuck on. I think I know the correct way to do it but from what I see when I visually graph I don't believe...

    Started by 12_eggs‎, 07-27-2015 04:21 PM
    • Replies: 0
    • Views: 1,509
    07-27-2015, 04:21 PM Go to last post
  33. Interpretation of Mantel-Haenszel Statistics

    We have conducted an experiment with 2 groups and a dichotomous outcome on 3 occasions and for each occasion we have a 2x2 contingency table. Rather...

    Started by Andybell321‎, 07-25-2015 10:36 AM
    categorical data analysis, mantel-haenszel
    • Replies: 0
    • Views: 1,357
    07-25-2015, 10:36 AM Go to last post
  34. Question The Future of Clinical Trials Biostatistics - Bayesian?

    I have noticed a trend with hiring managers to vault candidates that are well versed in Bayesian analysis to the top. This is not necessarily...

    Started by PRCarpenter‎, 07-22-2015 07:03 PM
    bayesian, biostatistician, clinical trials, jobs, philosophy
    • Replies: 1
    • Views: 890
    07-22-2015, 09:14 PM Go to last post
  35. Question on statistical method

    I have a data set (attached) that I am trying to analyze, specifically I am trying to determine if the independent variables 2,3,4,5,6,7,8 is...

    Started by iamrico00‎, 07-20-2015 08:56 PM
    • Replies: 0
    • Views: 1,538
    07-20-2015, 08:56 PM Go to last post
  36. How to analyze proportions from large datasets

    Hello all! This question will likely reveal my lack of basic statistics knowledge, but I can't seem to find the answer in textbooks or on this forum....

    Started by skaup‎, 07-20-2015 01:01 AM
    binary outcome, nominal data, proportions
    • Replies: 1
    • Views: 1,018
    07-20-2015, 02:23 AM Go to last post
  37. how to interpret or report the result

    i have done a project looking at how many malpositioned nasogastric tubes were detected on doing chest radiography in patients in ICU. can i report...

    Started by tahirrehmatullah‎, 07-16-2015 07:35 PM
    • Replies: 1
    • Views: 1,400
    07-17-2015, 07:43 AM Go to last post
  38. General Linear Model using proportions as raw data - transformation needed?

    Hi, I have become confused in my reading of analysis of proportions. I was all set to analyse my data using a general linear model after...

    Started by DeanP‎, 07-16-2015 11:12 PM
    general linear model, proportions, unequal sampling effort
    • Replies: 0
    • Views: 1,245
    07-16-2015, 11:12 PM Go to last post
  39. Request for help or orientation

    Hello. I am new here and I admit I suck at statistics. I need your help on how to solve a statistical problem. Please don't give the easy answers...

    Started by JorgeMota‎, 07-16-2015 05:44 PM
    • Replies: 1
    • Views: 922
    07-16-2015, 05:46 PM Go to last post
  40. Question Request for help on choosing a statistical test to determine the efficacy of a drug

    Hi, I'm an undergraduate working on a project concerning peptides. I have data for a group of 12 peptides that were tested against 4 types of...

    Started by SeurOre‎, 07-16-2015 09:06 AM
    amp, peptides
    • Replies: 0
    • Views: 1,294
    07-16-2015, 09:06 AM Go to last post
  41. Question Treating Dependent Variable (Ordinal 5 item likert scale variable)

    Hi all, I had a dependent variable of fatigue score in 4 cycles and i need to test with one Independent categorical variable which had 2...

    Started by sharfras‎, 07-13-2015 04:12 AM
    • Replies: 2
    • Views: 2,355
    07-15-2015, 04:39 AM Go to last post
  42. Another "which tests to use?" question

    Hi all, longtime lurker, first-time poster here. Reading people's questions and answers here really helped my understanding back when I was taking...

    Started by Werewolf‎, 07-11-2015 12:17 PM
    • Replies: 0
    • Views: 1,192
    07-11-2015, 12:17 PM Go to last post
  43. Request for advice on what statistical test to use for research on decision times

    Basically the research we are doing involves measuring the time taken for two dolphin subjects to make their decision in a Matching-to-Sample study....

    Started by Nithya‎, 07-09-2015 08:44 AM
    • Replies: 5
    • Views: 1,777
    07-11-2015, 02:41 AM Go to last post
  44. A couple of questions about results in computational neuroscience

    Hi guys, This is my first time posting here. I am a medical student and I have been conducting research in computational neuroscience over the...

    Started by ilzwalrus‎, 07-09-2015 12:32 PM
    • Replies: 0
    • Views: 1,179
    07-09-2015, 12:32 PM Go to last post
  45. Study on prevalence of disease

    Greetings! Can someone advise me on what is the appropriate name for the retrospective study of prevalence of certain disease within patients...

    Started by mukuwa‎, 07-07-2015 12:41 PM
    • Replies: 2
    • Views: 1,188
    07-08-2015, 01:56 PM Go to last post
  46. Clinical trial - stratified randomization

    Hi all, There is something very basic I don't get about stratified randomization and I was hoping you might be willing to help me with. Say I have...

    Started by LeeSG‎, 06-25-2015 05:18 AM
    clinical trial, randomization
    • Replies: 2
    • Views: 1,576
    07-02-2015, 11:54 AM Go to last post
  47. How do I chose between sensitivity/specificity and PPV/NPV?

    I have just finished a validation study, where two specialists used the available information to classify patients according to their diseases status...

    Started by marsh_randy‎, 06-29-2015 11:56 AM
    • Replies: 4
    • Views: 2,416
    07-02-2015, 03:01 AM Go to last post
  48. Incongruity between t-test and 2x2 repeated measures ANOVA/gain scores t-test/ANCOVA

    Hi, it's the first time I post here. Forgive me if my English is not always correct. I want to ask about an incongruity I found when analyzing data...

    Started by Artanis‎, 07-01-2015 10:54 AM
    • Replies: 4
    • Views: 1,455
    07-01-2015, 11:44 AM Go to last post
  49. Power analysis for Cox PH model

    Hello, I am new here but have searched the forum before posting. I am planning a retrospective review of previously collected data. N=480. ...

    Started by mirt2013‎, 06-25-2015 09:29 PM
    • Replies: 1
    • Views: 1,952
    06-29-2015, 02:02 PM Go to last post
  50. sutiable study design?

    Hi everyone. I would be thankful for any helpful advice regarding a suitable study design for a planned research. I have a series of approx. 100...

    Started by aphrux‎, 06-25-2015 01:10 PM
    • Replies: 0
    • Views: 1,210
    06-25-2015, 01:10 PM Go to last post
  51. Cluster analysis when two domains measure the same thing

    Hi all, first of all thank you for your help in advance. I have the following problem: I would like to perform a cluster analysis on my sample...

    Started by Rerun‎, 06-25-2015 09:48 AM
    • Replies: 0
    • Views: 882
    06-25-2015, 09:48 AM Go to last post
  52. Unit of Analysis

    Hi! Trying to determine which analysis is appropriate. Let me explain: -We have access to a community hospital records on the patient level....

    Started by jamesmartinn‎, 06-24-2015 02:00 PM
    • Replies: 0
    • Views: 1,115
    06-24-2015, 02:00 PM Go to last post
  53. Rate ratio interpretation for large estimates

    Hi all, Just a quick question - I have many rate ratios and the 95% CIs, most of which have narrow CIs and reasonable RRs (e.g., 1.23). I've been...

    Started by wernie‎, 06-18-2015 06:23 PM
    • Replies: 6
    • Views: 1,293
    06-23-2015, 06:11 PM Go to last post
  54. how does stata calculate confidence intervals for age standardised means/proportions

    Dear Stat Talkers! I'm using the following Stata command (see help mean): mean x, std(a) stdw(b) over(c) to get age-standardised mean or...

    Started by Amu‎, 06-23-2015 01:35 PM
    confidence interval, direct standardization, stata, weighting
    • Replies: 0
    • Views: 758
    06-23-2015, 01:35 PM Go to last post
  55. Identification of study design

    Hi all, I'm just trying to figure out what to call the study design for the way my research has been set up, so could use some help! I have...

    Started by wernie‎, 06-18-2015 06:37 PM
    • Replies: 2
    • Views: 2,485
    06-21-2015, 10:09 PM Go to last post
  56. What will be the best test to determine the significance in my study?

    The project does not have a simple design. It is planned as follows: 1. It is a longitudinal observation during 120 days in 48 subjects (with...

    Started by gomca‎, 06-19-2015 06:16 AM
    • Replies: 0
    • Views: 1,025
    06-19-2015, 06:16 AM Go to last post
  57. Conflicting Results Evaluating Proportional Hazards Assumption

    Hello, Currently working on a survival analysis of some lung cancer patients. I am building a Cox PH model and was working on validating the PH...

    Started by rhysticlight‎, 06-18-2015 02:10 PM
    cox, proportional hazards, survival analysis
    • Replies: 0
    • Views: 982
    06-18-2015, 02:10 PM Go to last post
  58. Randomized trial with repeated measure - which test?

    Hi, Im currently conducting a randomized placebo trial where we test the effect of one treatment on a single outcome variable. We measure the...

    Started by DrSander‎, 06-17-2015 02:16 AM
    • Replies: 3
    • Views: 1,652
    06-17-2015, 07:15 AM Go to last post
  59. PAF through formula or through Conditional Logistic Regression

    Hi all, In a large registry dataset of psychiatric patients, if one wants to find the excess risk of schizophrenia patients developing depression,...

    Started by Pure_Stats‎, 06-16-2015 10:07 AM
    biostatistics, conditional regression, epidemiology, medical statistics, regression model
    • Replies: 2
    • Views: 1,711
    06-17-2015, 05:38 AM Go to last post
  60. Meta-analysis of cross-sectional studies with both one and two study groups

    Hello, I have a question about a meta-analysis I would like to run, comparing outcome measure Y in 'patients' groups (patients) and 'healthy'...

    Started by RutgerAussie‎, 06-15-2015 10:25 PM
    • Replies: 5
    • Views: 1,887
    06-17-2015, 02:21 AM Go to last post

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