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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Help with biostatistical analysis for a study

    Hello. I need some guidance with respect to biostatistical analysis of my study data: Prospective study which studies the outcome of a surgical...

    Started by GreyGhostRos‎, Today 09:34 AM
    • Replies: 5
    • Views: 66
    Today, 08:42 PM Go to last post
  2. Best way to handle data

    Hello, I am running a one-arm study in which a scale result (blood ketones) are reported across two consecutive 28 day periods (Control...

    Started by researchrob‎, Today 11:40 AM
    • Replies: 0
    • Views: 27
    Today, 11:40 AM Go to last post
  3. Geospatial best fit - Histogram against continous measured data?

    Hi, I have some remote sensing images from which I extracted the pixel values as histogramms: Pixel value respectively classes 1 - 255 ...

    Started by tommyw‎, 11-20-2017 06:47 PM
    continous variable, histogram comparison
    • Replies: 0
    • Views: 99
    11-20-2017, 06:47 PM Go to last post
  4. Post evaluating performance

    Hi all: We've run up against a bit of a difficult scenario and we're looking for input on how to proceed. I will give some background on our data...

    Started by jamesmartinn‎, 11-16-2017 08:41 AM
    • Replies: 4
    • Views: 183
    11-20-2017, 07:56 AM Go to last post
  5. Average standard deviation?

    Hi Everyone, Sorry if a similar question has been asked before. I didn't see a thread focused on my particular query. I have a large dataset of...

    Started by peptideguy‎, 11-15-2017 03:04 PM
    • Replies: 1
    • Views: 102
    11-20-2017, 02:40 AM Go to last post
  6. Nonparametric data analysis

    I'm asking for advice. Topic of my research is brain iron accumulation. My task is the next . I have one dependent variable that is cathegorical and...

    Started by Mykola‎, 11-13-2017 03:24 PM
    2 Pages
    1 2
    confidence interval, corrections, logit, nonparametric, odds ratio., probability
    • Replies: 21
    • Views: 476
    11-18-2017, 07:59 PM Go to last post
  7. Question about meta-analysis

    Hello! I'm new here and I'm not a statistician but I would appreciate your inputs. Is it possible to make a meta-analysis investigating results...

    Started by termsndconditions‎, 11-07-2017 07:24 AM
    • Replies: 8
    • Views: 319
    11-10-2017, 10:33 AM Go to last post
  8. Statistical test for annual crude mortality trend (3 years data=3 data points)

    Help, I have the crude mortality figures for 2015, 2016, 2017 and would like to know if the figure for 2017 is statistically different. The...

    Started by JNelson‎, 11-08-2017 10:05 PM
    crude mortality, trend analysis
    • Replies: 1
    • Views: 124
    11-09-2017, 07:15 AM Go to last post
  9. What statistical test should I use?

    Hello, I am currently working on my thesis proposal and am having to state the proposed methods of my data analysis. I am focusing on two aims: 1)...

    Started by Victoria447‎, 11-06-2017 01:52 AM
    cross sectional, longitudinal, regression analysis, thesis
    • Replies: 1
    • Views: 203
    11-07-2017, 02:42 AM Go to last post
  10. Correlation between Platelet Count and Mean Platelet Volume

    I have attached my statistical analysis in this thread. It is about correlation between platelet count and mean platelet volume. I am conducting a...

    Started by IceFeast‎, 11-02-2017 02:37 AM
    • Replies: 0
    • Views: 193
    11-02-2017, 02:37 AM Go to last post
  11. P-Trend, what does it mean and how being calculated?

    Hello all :) I need your help... I am trying to make analysis based on a similar paper, and I can't understand the statistical method to be...

    Started by Yankel‎, 10-28-2017 12:29 PM
    • Replies: 0
    • Views: 254
    10-28-2017, 12:29 PM Go to last post
  12. [SPSS - Mixed Models] Repeated measurements data from randomised controlled trial

    I am analyzing data from a randomized clinical trial, with 2 intervention groups (placebo and intervention) and repeated measurements over time. I am...

    Started by Flightpete‎, 10-05-2017 11:25 AM
    control for, mixed effects model, randomized control trials, spss
    • Replies: 3
    • Views: 368
    10-22-2017, 05:59 AM Go to last post
  13. Means are not different but significant

    Hi. I have a query, generated from PrediXcan analysis but more related to statistics. I have the two means of predicted expression values for...

    Started by aqas‎, 10-20-2017 08:27 AM
    means difference, pvalues, significant
    • Replies: 1
    • Views: 373
    10-20-2017, 08:35 AM Go to last post
  14. Question Multiple t-tests vs ANOVA with Dunnett's post-hoc test

    Hello, I am bit confused about the use of multiple t-tests vs ANOVA with Dunnett's post-hoc test (on normally distributed data). Let's take the...

    Started by Biochemist‎, 10-14-2017 07:46 AM
    • Replies: 2
    • Views: 322
    10-14-2017, 12:18 PM Go to last post
  15. Retrospective chart review subject selection: case vs. control

    I did retrospective chart review on 240 subjects from my previous institute. THe study was on sedation required for bronchoscopy. The procedure used...

    Started by dr_pritish‎, 10-14-2017 10:37 AM
    chart review
    • Replies: 0
    • Views: 164
    10-14-2017, 10:37 AM Go to last post
  16. RCT: estimation of total sample size knowing only the percentage of occurrence

    Dear all, I was asked to estimate the minimum sample size to set up a RCT comparing a standard dose technique to detect recurrence of disease vs...

    Started by MDaniele‎, 10-12-2017 04:31 AM
    estimate, noninferiority, rct, sample size, trial
    • Replies: 0
    • Views: 148
    10-12-2017, 04:31 AM Go to last post
  17. Triangulating multiple data sources of prescription information

    I am currently working on a retrospective database study assessing the real-world effectiveness of a medication. I am faced with a few challenges. I...

    Started by vpmwar‎, 10-06-2017 11:59 AM
    agreement, cohens's kappa, correlation, triangulation
    • Replies: 0
    • Views: 205
    10-06-2017, 11:59 AM Go to last post
  18. Comparing the effectiveness of an intervention in two groups?

    Hi Everyone, I'm stuck trying to find a way to compare whether or not a given intervention has a greater effect in one group (Kids < 5) than...

    Started by jpgordon‎, 10-03-2017 10:29 PM
    • Replies: 1
    • Views: 188
    10-04-2017, 08:01 AM Go to last post
  19. Looking for a test to find if there is a relationship between 2 groups

    Hi all, I have a data set of two frequencies, one is the frequency of air temperature and the second is the frequency that an activity occurs at...

    Started by spulak‎, 10-02-2017 12:07 PM
    • Replies: 2
    • Views: 195
    10-02-2017, 03:37 PM Go to last post
  20. Block design anova

    I have a question about what the most appropriate anova design is for my data. I am posting here because I cannot seem to get the search function to...

    Started by vanguard605‎, 09-11-2017 03:52 PM
    anova, block design, community ecology
    • Replies: 2
    • Views: 467
    09-29-2017, 08:35 AM Go to last post
  21. Using logistic regression to compute age-adjusted rates

    Dear All, Would anybody please give me a breakdown no how to compute "age-adjusted proportions" based on the logistic regression coefficients? ...

    Started by Raok‎, 09-15-2017 06:53 AM
    • Replies: 4
    • Views: 616
    09-22-2017, 10:02 AM Go to last post
  22. Interpreting significance based on confidence interval

    Hi Everyone, Could some of you help to interpret my results based on p values and confidence intervals? A little bit of background: I am trying to...

    Started by julian_DE‎, 09-21-2017 07:48 AM
    • Replies: 3
    • Views: 367
    09-22-2017, 05:04 AM Go to last post
  23. Repeated measures with varying count between group

    I'll explain my problem a bit: I have two groups S(story) and P(picture). Each is composed of the same 48 subjects. My endpoint is a 'score' on an...

    Started by qjuice‎, 09-18-2017 06:46 PM
    • Replies: 5
    • Views: 482
    09-20-2017, 05:05 PM Go to last post
  24. Switch of distribution during observation period (Scratch Assay)

    Dear Stats-Talkers, I performed several Scratch Assays (its an experiment where cells close a cell-free gap over time, see also attached file I)...

    Started by Peters‎, 09-12-2017 04:00 AM
    • Replies: 0
    • Views: 310
    09-12-2017, 04:00 AM Go to last post
  25. Modeling and predicting pathology from multivariate clinical data

    Hello, I have a clinical data set that consists of 5 clinical measurements on thousands of tissue samples. Furthermore, each sample has a pathology...

    Started by jason.parker‎, 09-09-2017 04:50 PM
    biostats, cancer, prediction
    • Replies: 2
    • Views: 268
    09-11-2017, 09:55 AM Go to last post
  26. what statistical test to choose (large smple size)

    Hi all, I need to perform a test which shows if there is a statistical difference between males and females in getting diagnosis. I believe I should...

    Started by bburugap‎, 09-09-2017 08:34 PM
    • Replies: 2
    • Views: 351
    09-10-2017, 09:48 AM Go to last post
  27. Chi square p value <0.01 but graph pad prompts not valid

    Hello all, i have used graph pad prism to calculate p- value. my contingency table contains some observed frequencies which are 0. my p-value has...

    Started by Tiya‎, 09-09-2017 12:52 PM
    • Replies: 1
    • Views: 232
    09-09-2017, 01:09 PM Go to last post
  28. Poll Poll: Similarity instead of differences in means b/w 2 groups

    Hi - long time lurker. First time poster. I'm hoping folks can provide guidance and opinions. I am looking at a small pilot study (n=16) of...

    Started by drtoddchang‎, 08-28-2017 12:16 AM
    equivalence, heart rate, paired, wilcoxon signed
    • Replies: 4
    • Views: 655
    08-28-2017, 03:33 PM Go to last post
  29. Is Chi-square appropriate for a single measurement variable with repeated measures?

    Hi! I am looking at how many burrows are occupied by a skink species at eight sites across a property. Counts of the number of occupied burrows...

    Started by RustyEcologist‎, 08-22-2017 11:54 PM
    • Replies: 2
    • Views: 397
    08-24-2017, 06:20 PM Go to last post
  30. One way ANOVA vs Kruskal Wallis

    Hi, I am comparing four groups (measurements of bone thickness and other bone parameters). The distributions are normal (Kolmogorov–Smirnov test)...

    Started by n.lu‎, 08-23-2017 05:04 AM
    kruskal wallis, nonparametric, one way anova, parametric
    • Replies: 1
    • Views: 491
    08-23-2017, 08:38 AM Go to last post
  31. Question Can I calculate the % of people positive for an outcome from an odds ratio?

    Hi, Thanks for looking at my question. Background I am doing a systematic reveiw and metanalysis, essentially on diagnostic test accuracy and...

    Started by SSSA‎, 08-18-2017 10:09 AM
    odds ratio
    • Replies: 8
    • Views: 459
    08-21-2017, 02:45 AM Go to last post
  32. Cox Regression with missing values

    Very grateful for any advice. I'm trying to perform Cox regression on a data set with multiple random missing values. SPSS is my go-to software,...

    Started by Rowena‎, 08-13-2017 04:36 AM
    cox regression, missing values, sas, spss
    • Replies: 5
    • Views: 610
    08-17-2017, 05:06 AM Go to last post
  33. Best scenario: unpaired or paired situation?

    I have a few questions, but first let me give you some necessary background of the experiment and the underlying questions. Basically, the design...

    Started by tleal‎, 08-15-2017 11:37 AM
    hypothesis testing, matched, paired, pairing, unpaired
    • Replies: 0
    • Views: 391
    08-15-2017, 11:37 AM Go to last post
  34. Freidman test with missing values?

    I have a set of data at four time points, but some subjects only two out of the four time points. Can I still use Friedman test for this in SPSS?

    Started by zhu‎, 08-15-2017 11:34 AM
    • Replies: 0
    • Views: 218
    08-15-2017, 11:34 AM Go to last post
  35. Propensity Score Matching

    Hi! I'm conducting a retrospective study in which we want to analyze time period of 60 days before occurence of a particular adverse event. To do...

    Started by joanna513‎, 08-09-2017 07:06 AM
    propensity score matching
    • Replies: 1
    • Views: 490
    08-09-2017, 08:56 AM Go to last post
  36. Poisson Standard Deviation

    Hi! Just a sanity check as I have to do a few computations for a report manually. Our indicator is defined in the following way: #...

    Started by jamesmartinn‎, 06-05-2017 10:03 AM
    • Replies: 6
    • Views: 1,104
    08-08-2017, 09:34 PM Go to last post
  37. Normal Approximation, Fisher's Exact Test, Relative Risk or Odds Ratio?

    A clinical trial is being planned, in which the primary outcome is binary (success/failure). There are two treatment groups (treatment/control). The...

    Started by WeeG‎, 06-17-2017 01:06 PM
    • Replies: 7
    • Views: 993
    08-08-2017, 09:33 PM Go to last post
  38. Help with correct statistical analysis?

    I am conducting an audit into vitamin D deficiency in children. I have the mean serum concentrations of vitamin D in specific areas (postcodes)...

    Started by MedStudent‎, 07-03-2017 05:54 PM
    • Replies: 5
    • Views: 852
    08-08-2017, 09:32 PM Go to last post
  39. Statistical significance

    Hi, I have the following problem and I would need some piece of advice to solve it: I have a group of 28 patients (17 survived, 11 died) and I...

    Started by Carcassonne‎, 07-10-2017 02:51 AM
    • Replies: 8
    • Views: 780
    08-08-2017, 09:31 PM Go to last post
  40. Critiquing a Network Meta-analysis: Interpreting inconsistency

    Hi all. I'm a non-statistician trying to critique a network meta-analysis on a group of migraine medications called triptans (PDF link). The...

    Started by networkMA‎, 07-18-2017 02:18 PM
    • Replies: 3
    • Views: 456
    08-08-2017, 09:30 PM Go to last post
  41. Exclamation STATA Logistic Regression Intepretation

    Hi, My dependent variable is goes to college coded 0=No and 1= Yes. I am not sure how STATA reads/ranks the dependent variable....thus I am not...

    Started by I_AM_KB‎, 08-03-2017 02:53 PM
    interpreting odds ratios, logistic regression, stata
    • Replies: 0
    • Views: 415
    08-03-2017, 02:53 PM Go to last post
  42. Sphericity with unequal sample sizes

    Hello, I want to do a repeated measures anova in R on a data set consisting of four treatments on subjects, over 4 weeks. However, in week 3 I am...

    Started by Wouterka‎, 07-30-2017 11:21 AM
    • Replies: 0
    • Views: 413
    07-30-2017, 11:21 AM Go to last post
  43. Question Need Appropriate Test for comparing a series of measurements from one bone to another

    My research involves taking measurements at 9 sections at different locations on the shaft of bones. I am having trouble determining which...

    Started by SierraS‎, 07-13-2017 11:58 PM
    bone, pair, series, test
    • Replies: 2
    • Views: 614
    07-23-2017, 08:41 PM Go to last post
  44. Online Biostatistics Course/Master's Degree

    Hi everyone, I'll be glad if someone could recommend me some online Biostatistics Course or Master's Degree for beginner. Thanks!

    Started by ovallecc‎, 07-20-2017 03:07 AM
    • Replies: 1
    • Views: 699
    07-20-2017, 04:23 AM Go to last post
  45. Patient-year Incidence rates comparisons and p value

    Dear all, I would like to statistically compare two incidence rates from two different groupes. I found the Incidence rate difference (IRD)...

    Started by didye‎, 07-19-2017 04:43 AM
    compare rates, incidence rate, ird
    • Replies: 0
    • Views: 434
    07-19-2017, 04:43 AM Go to last post
  46. Help with comparing disease death rates over time

    Hello everyone, I am working with a national mortality file and have pulled certain deaths for a particular disease and created crude rates by...

    Started by LAM_13‎, 07-17-2017 07:03 PM
    • Replies: 0
    • Views: 1,319
    07-17-2017, 07:03 PM Go to last post
  47. Software for NHANES Analysis

    Hello! I'm going to be using NHANES data for some of my research looking at dietary factors and health-related outcomes. I have a bit of exposure to...

    Started by mam326‎, 07-14-2017 04:25 PM
    • Replies: 0
    • Views: 505
    07-14-2017, 04:25 PM Go to last post
  48. Multi-level Meta-regression using random effect for treatment? [R pkg metafor]

    I am a biostatistician consulting on a meta-analysis of 16 studies each w/ 2 treatment arms. The main interest is in the effect of the variable...

    Started by chelbylu‎, 07-06-2017 03:45 AM
    hierarchical model, meta-regression, r metafor, random effects, treatment
    • Replies: 0
    • Views: 530
    07-06-2017, 03:45 AM Go to last post
  49. Help choosing right statistics

    The experiment consisted of testing the effect of several diets on the weight of fish. I want to check what groups differ from each other. There is...

    Started by Andre Barreto‎, 06-26-2017 02:58 PM
    • Replies: 2
    • Views: 755
    06-26-2017, 04:06 PM Go to last post
  50. sample size calculation for chi square test with more than 2 groups

    Greetings everybody I'm running a sample size estimation for a study that will use chi square test of association for the qualitative comparison of...

    Started by Bassam‎, 06-07-2017 06:23 PM
    • Replies: 4
    • Views: 1,437
    06-08-2017, 10:58 AM Go to last post
  51. test for cumulative analysis of outcomes over time in meta-analysis

    A systematic review and meta-analysis I am reading references having tested for chronological cumulative analysis for the effects of the outcomes...

    Started by Roundtoit‎, 06-02-2017 05:41 PM
    • Replies: 3
    • Views: 1,335
    06-04-2017, 03:02 PM Go to last post
  52. Simple question re retrospective study types

    Hi, Please could someone confirm that I'm using the correct terminology to describe two studies listed below. I think that they are both...

    Started by ConnemaraPony‎, 05-30-2017 01:31 PM
    • Replies: 2
    • Views: 1,754
    05-30-2017, 03:48 PM Go to last post
  53. Non Inferiority with a Historical Control

    Is it possible or valid to do a Non-Inferioirty Test againts a historical control. I should point out for the historical control all I have is a...

    Started by polc1410‎, 05-30-2017 04:09 AM
    • Replies: 1
    • Views: 1,030
    05-30-2017, 08:46 AM Go to last post
  54. Should I perform a PCA on my datas?

    Hi, I'm new to the statistic world. I have doubts about pca. I am performing the statistics of my study and I have a lot of data. I wonder if I can...

    Started by Clarissa‎, 05-26-2017 08:36 AM
    • Replies: 0
    • Views: 1,015
    05-26-2017, 08:36 AM Go to last post
  55. covariate for only clinical group

    HI I have tried to find an answer on the web but was not able, and will appreciate your help! I have a question regarding the use of a covariate in...

    Started by newbeeme‎, 05-21-2017 01:48 AM
    • Replies: 3
    • Views: 1,588
    05-22-2017, 09:28 AM Go to last post
  56. Absolute values or Log-transformed data

    I want to perform a non parametric test (mann-whitney) for my experiments that is briefly quantification of viral load (Real Time Polymerase chain...

    Started by julian_DE‎, 05-15-2017 01:06 AM
    • Replies: 3
    • Views: 1,296
    05-15-2017, 08:55 PM Go to last post
  57. Smile Mixed Model Analysis SPSS

    Hello All, I have a data set which I am trying to find out what is the best way to go about analyzing. I have been asking around and was advised...

    Started by quix09‎, 05-15-2017 08:24 AM
    • Replies: 0
    • Views: 1,086
    05-15-2017, 08:24 AM Go to last post
  58. Is Cochran's Q the right test for repeated measures with binary outcomes?

    Hi, I am trying to analyze a data set. The question we are looking at is whether the rate of a successful outcome and the risk of a...

    Started by Jennifer Kosty‎, 05-12-2017 12:15 PM
    • Replies: 0
    • Views: 969
    05-12-2017, 12:15 PM Go to last post
  59. Different proportions in different conditions?

    Hi, I am struggling with the proper way to analyze my data. I did some research in and out of this forum but could not find the answer to my...

    Started by Fanny-‎, 04-11-2017 08:06 AM
    • Replies: 3
    • Views: 2,070
    05-07-2017, 03:06 AM Go to last post
  60. GLM with non-linear predictor

    Hi, I am analyzing a dataset looking at procedural skill development. The data itself is binomial, whether or not a procedure was successful. When...

    Started by amw2320‎, 05-06-2017 11:02 PM
    • Replies: 0
    • Views: 948
    05-06-2017, 11:02 PM Go to last post

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