1. 10-14-2010
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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Exclamation Evaluation of correlation trend

    I would like to ask you for help and advice regarding one comment I received during the peer-review process for manuscript I submitted. My colleagues...

    Started by mzmph‎, 01-21-2017 07:19 PM
    correlation analysis
    • Replies: 1
    • Views: 96
    Yesterday, 07:43 PM Go to last post
  2. Clinical Trial Simulator - Your feedback is welcomed!

    Hi all I hope it's alright if I introduce my clinical trial simulator app here. It's free and you can use it online to simulate a trial, check it...

    Started by mzhKU‎, 01-15-2017 11:33 AM
    • Replies: 4
    • Views: 314
    Yesterday, 10:40 AM Go to last post
  3. McNemar or Chi sqared test for case-control study

    Dear all, I'm facing a dilemma which test would be appropriate to compare frequency of a feature in two age, sex and...

    Started by Markica85‎, 01-20-2017 06:59 AM
    • Replies: 3
    • Views: 196
    01-21-2017, 03:55 PM Go to last post
  4. Shiny App - Forest Plots

    Hi I've created a shiny app a while back that will create forest plots based on user supplied data through (a) uploading a data file (b)...

    Started by jamesmartinn‎, 01-16-2017 09:06 AM
    • Replies: 0
    • Views: 161
    01-16-2017, 09:06 AM Go to last post
  5. correlation study - Is my sample size too small?

    Hi there! i'm a pediatrician working in the neonatal ward, and i've recently finished aquiring data about a study that i'm doing - i'm trying to...

    Started by galkim‎, 01-15-2017 04:39 AM
    • Replies: 4
    • Views: 192
    01-16-2017, 02:17 AM Go to last post
  6. Multilinear regression?

    Hi, all: I need help for my research. I would like to develop an analytical method to detect the toxin A metabolites in exposed human urine; I...

    Started by ybz12003‎, 01-14-2017 06:34 PM
    • Replies: 1
    • Views: 153
    01-15-2017, 07:05 AM Go to last post
  7. Power analysis with one and two variables?

    Hi gang, I am severely illiterate in stats and so am struggling with what would seem to be a very straightforward problem. My problem: We...

    Started by ablum‎, 01-04-2017 04:18 PM
    • Replies: 1
    • Views: 335
    01-11-2017, 04:50 PM Go to last post
  8. Question on Odds ratio

    Hi, I have a basic understanding of odds ratio. I can't figure out how to integrate the space S into my odds ratio equation. For the following...

    Started by MinieMe‎, 01-10-2017 01:13 PM
    biostatistics, odds ratio
    • Replies: 2
    • Views: 165
    01-10-2017, 02:38 PM Go to last post
  9. Post What statistical test to use for species abundance between wet and dry season?

    Sorry if this question is trivial, I have a collection of camera trap data of recorded species during the rainy season and the dry season. I am...

    Started by BondHR‎, 01-07-2017 10:24 PM
    abundance, camera trap data, rstats, species data, statistics
    • Replies: 5
    • Views: 280
    01-08-2017, 02:38 PM Go to last post
  10. Temporal Distribution of Death

    Dear all, I plan to conduct a study. The preliminary aim is to examine the temporal distribution of death of terminal cancer patients in hospice...

    Started by bestmic‎, 12-20-2016 06:40 AM
    • Replies: 10
    • Views: 617
    01-03-2017, 04:40 AM Go to last post
  11. Add AUCs

    I want to add Area Under the Curve (AUC) from multiple meta analyses. AUC for each Meta analysis is given. How can I add them together?

    Started by Michael_svm‎, 12-20-2016 05:24 AM
    area under the curve, auc, diagnostic, roc
    • Replies: 6
    • Views: 472
    12-23-2016, 08:08 AM Go to last post
  12. Patterns in DNA, seperating signal from noise -- outliers?

    Hello all, I'm looking at patterns in fragments of RNA. What I need to do is separate the signals from noise in Exons (small regions of DNA/RNA)....

    Started by James1984‎, 10-10-2015 06:30 PM
    • Replies: 2
    • Views: 655
    12-22-2016, 05:05 AM Go to last post
  13. t-test or z-test for two proportions?

    We did an intervention to reduce the frequency of use of a certain type of treatment and now I want to compare the data pre vs post intervention. ...

    Started by hurricanemb‎, 12-18-2016 03:28 PM
    proportions, t-test, z-test
    • Replies: 3
    • Views: 270
    12-19-2016, 11:01 AM Go to last post
  14. Red face Interpreting Odds Ratios... weird question

    Hi, I sort of have a weird question. I have a basic understanding of ORs, and can interpret them, but it's never been clear to me why we...

    Started by Ceci18‎, 12-14-2016 10:34 AM
    • Replies: 6
    • Views: 409
    12-16-2016, 11:37 AM Go to last post
  15. Area under Kaplan Meier curve

    There is one thing bothering me for some time: What does area under Kaplan-Meier survival curve actally represent? Is there a plausible way to...

    Started by Markica85‎, 12-10-2016 05:55 AM
    kaplan meier, survival analysis
    • Replies: 0
    • Views: 408
    12-10-2016, 05:55 AM Go to last post
  16. Pooling time points to perform a Fisher test?

    Hello, I am currently trying to analyse an experiment to assess if rats with cerebral malformations have a sensitivity deficit on one of their...

    Started by Fanny-‎, 12-07-2016 12:10 PM
    anova, chi-square, fisher test
    • Replies: 4
    • Views: 409
    12-09-2016, 03:58 AM Go to last post
  17. What kind of statistical test can be used for my data?

    It is my first post on this forum so please be gentle. If it is not a proper section I would appreciate if moderator moves the thread to the correct...

    Started by Shaxi Liver‎, 12-07-2016 11:56 AM
    • Replies: 1
    • Views: 258
    12-07-2016, 01:27 PM Go to last post
  18. How to obtain an unbiased post-stratified estimator for survival probabilities?

    Suppose I have estimated the survival probabilities $\hat{S(t)}_1, \hat{S(t)}_2, \ldots, \hat{S(t)}_H$ from $H$ strata. Now I want to get an unbiased...

    Started by Blain Waan‎, 08-12-2016 09:14 PM
    estimator, stratification, survival
    • Replies: 3
    • Views: 641
    12-06-2016, 11:07 AM Go to last post
  19. Why not use Kaplan Meier?

    In the method described here http://dmkd.cs.vt.edu/papers/TKDE17.pdf R code implementation is provided ...

    Started by pablrodr‎, 12-02-2016 04:07 PM
    exponential distribution, kaplan meier, weibull distribution
    • Replies: 5
    • Views: 367
    12-03-2016, 09:56 AM Go to last post
  20. Bird Community Ecology - BACI experiment

    Greetings! I'm currently trying to investigate the impact of an event on the bird community of a National Park on my country. For that I have...

    Started by Fsmelo‎, 12-02-2016 10:36 AM
    baci, community ecology, ecology
    • Replies: 2
    • Views: 280
    12-02-2016, 03:19 PM Go to last post
  21. How to use chi-square test correspondence between features and response in R?

    There is a set of tumors,each one includes five features, which relate to one gene type result. Tumor Feature 1 ... Feature 5 Gene type 1 ...

    Started by l35633‎, 11-27-2016 12:56 PM
    chi-square, features, response
    • Replies: 0
    • Views: 327
    11-27-2016, 12:56 PM Go to last post
  22. MDS vs ANOVA / GLM methods - how and why?

    Hello to all :wave: I am a new member of this forum and the reason why I ended up here is the following: like many others, I am in desperate need of...

    Started by caralynne‎, 11-26-2016 06:17 AM
    • Replies: 0
    • Views: 330
    11-26-2016, 06:17 AM Go to last post
  23. How the estimate a smple size ?

    Hi everybody; I am a PhD student, my thesis focuses on the study of reproductive health among teenagers girls . For that, I'am going to work in...

    Started by siham‎, 11-24-2016 05:41 PM
    • Replies: 2
    • Views: 372
    11-25-2016, 12:15 PM Go to last post
  24. Help with linear model

    Hi guys, I'm really struggling with the relevant coding for this, I'm using Rstudio. I need a Linear model with Gaussian error structure to find...

    Started by imbricata‎, 11-07-2016 05:07 AM
    • Replies: 1
    • Views: 372
    11-23-2016, 10:51 AM Go to last post
  25. Model Selection in Survival Analysis

    I'm having trouble with parametric model selection in survival analysis. I founded this sequence of steps in some presentation. This is an...

    Started by askazy‎, 11-20-2016 02:53 PM
    • Replies: 1
    • Views: 313
    11-23-2016, 10:44 AM Go to last post
  26. estimating start point of a production of y" -ie findx for y=0 given y values for x>0

    I hope I can explain the problem clearly and its not an obvious solution. the application area is say an event (in the body) at say day=0 starts the...

    Started by azStats‎, 11-07-2016 09:47 AM
    • Replies: 3
    • Views: 375
    11-23-2016, 04:29 AM Go to last post
  27. Help with calculating probability?

    I have a strange set of data, it was counting the number of animals entering and leaving a shelter as a 'count' of how many were in the shelter. We...

    Started by zoologist‎, 11-22-2016 07:55 PM
    • Replies: 0
    • Views: 265
    11-22-2016, 07:55 PM Go to last post
  28. Exclamation Experimental design: Gender comparison in a novel memory matrix.

    Hello, I am a medical student who knows very little about biostats and would like some one to tell me whether my analysis for my research makes...

    Started by Syeda‎, 11-20-2016 06:13 AM
    • Replies: 4
    • Views: 384
    11-22-2016, 07:55 AM Go to last post
  29. Proportional hazards and Cox Model

    I'm trying to fit a Cox model, but there is some problems. I have the following variables in the model. - Group: 1, 2, ..., 9 - Sex: 1 female...

    Started by askazy‎, 11-09-2016 04:29 PM
    • Replies: 5
    • Views: 711
    11-10-2016, 12:42 PM Go to last post
  30. Cumulative Incidence with Confidence Intervals when using IPTW

    Dear Stata users, I'm doing a time to event analysis with inverse probability of treatment weights(IPTW) estimated with propensity scores from a...

    Started by Soren‎, 11-10-2016 10:41 AM
    cumulative incidence, iptw, propensity scores
    • Replies: 2
    • Views: 335
    11-10-2016, 12:01 PM Go to last post
  31. Help with setting my study!

    Hi all, I'm a newbie to biostatistics and I'm trying to figure out how to set the statistical part of my final project. I'm a dentistry student and...

    Started by Deepchamfer‎, 11-08-2016 09:14 AM
    • Replies: 1
    • Views: 354
    11-08-2016, 09:16 AM Go to last post
  32. Parallel and subsequential diagnostic tests

    Hey guys, i just ran into a problem: I am having two predictive models: Model 1: Sensitivity: 0.8 Specificity: 0.4

    Started by lilchaos‎, 11-02-2016 10:25 AM
    • Replies: 12
    • Views: 646
    11-08-2016, 02:59 AM Go to last post
  33. Dataset for statistical analysis

    Dear all, I work in Rome for the Italian National Health Service (www.iss.it); I am currently working on a European clinic project called EMTICS...

    Started by mtallon‎, 10-17-2016 03:09 PM
    • Replies: 4
    • Views: 518
    11-07-2016, 04:55 AM Go to last post
  34. Please help me select the correct statistical test

    I'm a general surgery resident and am conducting a quality improvement study about waste in the OR. My statistics background is limited to what I was...

    Started by billingsmd‎, 11-06-2016 05:59 PM
    • Replies: 5
    • Views: 406
    11-07-2016, 02:08 AM Go to last post
  35. Medical news story - Is this an OK way to report the stats?

    I'm a medical writer covering an upcoming research paper. I'm new to the forum, so please LMK if this is not an appropriate place for my question. ...

    Started by tobmed‎, 11-04-2016 09:49 AM
    • Replies: 2
    • Views: 418
    11-04-2016, 01:40 PM Go to last post
  36. Observed difference between two test for same patient is due to chance?

    Hi, I have results from two very sensitive but different lab test trying to find pathogen in a patient sample. For some patients results from two...

    Started by deepbiomed‎, 11-02-2016 02:02 PM
    • Replies: 0
    • Views: 301
    11-02-2016, 02:02 PM Go to last post
  37. likelihood ratio test and AIC

    Can somebody please help me answer the question in the attachment. I have a test next week. please help

    Started by Jeff Hardy‎, 10-31-2016 12:47 PM
    • Replies: 5
    • Views: 451
    11-02-2016, 12:40 PM Go to last post
  38. Help with correct model formula for a repeated measures design

    Hi there, I will really appreciate some help denoting the proper formula to fit a GLM for the following repeated measures data: I investigated...

    Started by phmontoya‎, 11-01-2016 11:45 AM
    • Replies: 0
    • Views: 313
    11-01-2016, 11:45 AM Go to last post
  39. Question about sample size penalty for looking at data mid-trial

    Hi, we're running a clinical trial for a skin treatment with a medical device that has a strong effect. We are using an inter-patient control (no...

    Started by bma449‎, 10-24-2016 05:58 PM
    interim analysis
    • Replies: 3
    • Views: 504
    10-29-2016, 02:08 PM Go to last post
  40. Help with regards to deciding appropriate statistical test for success criteria

    Hello, I have the collective data of 35 eyes that underwent trabeculectomy surgery for glaucoma control. There is no control group, and...

    Started by neosage‎, 10-27-2016 02:27 PM
    • Replies: 1
    • Views: 339
    10-27-2016, 06:00 PM Go to last post
  41. Converting GEE and MIXED from SAS to SPSS

    Hello, Im trying to do data analysis with GEE and/or Mixed models but get stuck in choosing the right SPSS syntax. I have data from subjects...

    Started by hoipiepeloi‎, 10-25-2016 05:37 PM
    gee mixed
    • Replies: 0
    • Views: 301
    10-25-2016, 05:37 PM Go to last post
  42. Help for sample size calculation

    in my prospective cohort study I will assess the serum level of a vitamin in a group of patients the normal reference serum range is 10-30 in normal...

    Started by emmyomran‎, 10-22-2016 01:04 PM
    sample size, sample size calculation
    • Replies: 1
    • Views: 451
    10-23-2016, 12:37 PM Go to last post
  43. Correlated variables in Cox model - which one is best

    Hi there, I am building a Cox model. I have two variables that are different measures of the same thing and they are therefore correlated with each...

    Started by dhmallon‎, 10-23-2016 10:27 AM
    cox proportional hazards, survival, variable selection
    • Replies: 0
    • Views: 336
    10-23-2016, 10:27 AM Go to last post
  44. HELP with data collection methods and data analysis in quantitative research : )

    I am doing a research proposal on the effect of a drug on haemorrhage growth in traumatic brain injury. My null hypothesis: TXA does not reduce the...

    Started by murrayk‎, 10-21-2016 10:11 PM
    • Replies: 1
    • Views: 339
    10-22-2016, 01:53 AM Go to last post
  45. Appropriate statistical test for HR's comparison between 2 population

    In case of 2 population, the first has HR X for the study's outcome (between the exposed and non-exposed groups), and the second has HR of Y (between...

    Started by ronitrot‎, 10-20-2016 10:03 AM
    • Replies: 1
    • Views: 461
    10-21-2016, 07:02 AM Go to last post
  46. Which statistical test to use for my data analysis

    Hi everyone, Could someone help me to know which statistics should i use for my data analysis. I did my project on "personal exposure...

    Started by Biosapien‎, 10-15-2016 02:52 PM
    • Replies: 4
    • Views: 507
    10-19-2016, 06:39 AM Go to last post
  47. Recurrent Event Survival Analysis

    Hi there, I'm working on a research on individuals who enter financial distress using the Cox proportional hazards model. In this case the...

    Started by Mkkl‎, 10-17-2016 08:46 AM
    cox proportional hazard, recurrent events, survival analysis
    • Replies: 0
    • Views: 308
    10-17-2016, 08:46 AM Go to last post
  48. Sample Size Calculation (HELP!)

    Hi all, I wish someone could help me out. I am trying to estimate the sample size for a national health survey. From the previous report,...

    Started by chummsy‎, 10-12-2016 09:30 PM
    • Replies: 1
    • Views: 410
    10-14-2016, 06:22 AM Go to last post
  49. Best Method for Comparison of Bacterial Community Compositions

    Hi! I have curated 454 pyrosequencing data using Mothur. I have clustered reads from each sample into OTUs at a unique level. (Please see attached...

    Started by samche42‎, 10-06-2016 10:17 AM
    • Replies: 0
    • Views: 437
    10-06-2016, 10:17 AM Go to last post
  50. Markov Process to estimate time until death

    Are there any websites that show examples of data setup and SAS code using some sort of Markov model to estimate time until or probability of death?...

    Started by lancearmstrong1313‎, 10-05-2016 01:14 PM
    • Replies: 0
    • Views: 387
    10-05-2016, 01:14 PM Go to last post
  51. Which comparison of means test to use?

    I've got myself confused about which test to use. I have done a cross sectional survey exploring the difference between pain as measured with a...

    Started by jackdog3‎, 10-04-2016 07:06 AM
    • Replies: 1
    • Views: 439
    10-04-2016, 12:14 PM Go to last post
  52. comparing sensitivity, specificity, and PPV of different cohorts-is it possible?

    hello and thanks in advance for helping out! i hope that my questions will not be terribly on-profesional .. i'm trying to figure how to compare...

    Started by mrnogi‎, 10-03-2016 04:57 PM
    • Replies: 2
    • Views: 347
    10-04-2016, 12:24 AM Go to last post
  53. Poll: How do you handle subjects having very different patterns?

    Good day everyone - I am curious as to what you all do in these situations. If you are running a sleep study, and you are simply using two...

    Started by allie_moore‎, 09-26-2016 12:35 PM
    • Replies: 2
    • Views: 479
    09-26-2016, 01:14 PM Go to last post
  54. Estimating main effects in a two factorial log linear model when applied to RNA-seq

    Hi everybody, I'm going to apply multiDE, an R package for detection of DEG in multiple treatment conditions, on some RNA-seq time series data......

    Started by Fate.gh‎, 09-16-2016 03:29 PM
    log-linear, rna-seq
    • Replies: 0
    • Views: 602
    09-16-2016, 03:29 PM Go to last post
  55. Survival analysis

    Hi there, I am doing some breast cancer survival analysis on population-based registry data...I have outlined to estimate incidence trends and...

    Started by MAYA85‎, 09-15-2016 03:28 PM
    • Replies: 2
    • Views: 508
    09-16-2016, 05:20 AM Go to last post
  56. What test to use?

    Hi all, I am new to statistics. Now, I am doing a research but I don't know which test to use. Basically, I have four groups with both positive...

    Started by Upupgo‎, 09-14-2016 02:50 PM
    • Replies: 1
    • Views: 427
    09-14-2016, 03:54 PM Go to last post
  57. Question R caret package: problems understanding the functions in confusionMatrix

    Hey, I earlier posted about the problematic interpretation of PPV (positive predictive value). As there seems to be no easy solution for that I...

    Started by lilchaos‎, 09-02-2016 09:17 AM
    • Replies: 2
    • Views: 566
    09-13-2016, 02:44 AM Go to last post
  58. Talking Analysing pre- and post-treatment lactate curves

    Good morning all, Has anyone got experience with analysing lactate against power curves? I have pre- and post-treatment lactate curves for 10...

    Started by WildlifeStats‎, 09-12-2016 04:21 AM
    curve, curves
    • Replies: 0
    • Views: 367
    09-12-2016, 04:21 AM Go to last post
  59. [SPSS - post hoc analysis and Logistic regression] When the result don't line up

    I'm a medical student doing his research interneship. We're currently investigating if there's a link between motoric and mental outcome and MRI...

    Started by j0hnj0hn‎, 09-08-2016 06:34 AM
    fisher exact test, logistic regression, medicine, post hoc tests
    • Replies: 0
    • Views: 429
    09-08-2016, 06:34 AM Go to last post
  60. How to evaluate significance.

    Hi, I have 58 samples and an enrichment analysis was done to each of them. So for each sample I have a list of enriched terms. I've collected the...

    Started by MinieMe‎, 09-06-2016 12:14 PM
    • Replies: 0
    • Views: 432
    09-06-2016, 12:14 PM Go to last post

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