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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Interpreting significance based on confidence interval

    Hi Everyone, Could some of you help to interpret my results based on p values and confidence intervals? A little bit of background: I am trying to...

    Started by julian_DE‎, Yesterday 07:48 AM
    • Replies: 2
    • Views: 119
    Today, 01:35 AM Go to last post
  2. Repeated measures with varying count between group

    I'll explain my problem a bit: I have two groups S(story) and P(picture). Each is composed of the same 48 subjects. My endpoint is a 'score' on an...

    Started by qjuice‎, 09-18-2017 06:46 PM
    • Replies: 5
    • Views: 213
    09-20-2017, 05:05 PM Go to last post
  3. Using logistic regression to compute age-adjusted rates

    Dear All, Would anybody please give me a breakdown no how to compute "age-adjusted proportions" based on the logistic regression coefficients? ...

    Started by Raok‎, 09-15-2017 06:53 AM
    • Replies: 3
    • Views: 252
    09-19-2017, 03:04 PM Go to last post
  4. Switch of distribution during observation period (Scratch Assay)

    Dear Stats-Talkers, I performed several Scratch Assays (its an experiment where cells close a cell-free gap over time, see also attached file I)...

    Started by Peters‎, 09-12-2017 04:00 AM
    • Replies: 0
    • Views: 207
    09-12-2017, 04:00 AM Go to last post
  5. Block design anova

    I have a question about what the most appropriate anova design is for my data. I am posting here because I cannot seem to get the search function to...

    Started by vanguard605‎, 09-11-2017 03:52 PM
    anova, block design, community ecology
    • Replies: 0
    • Views: 139
    09-11-2017, 03:52 PM Go to last post
  6. Modeling and predicting pathology from multivariate clinical data

    Hello, I have a clinical data set that consists of 5 clinical measurements on thousands of tissue samples. Furthermore, each sample has a pathology...

    Started by jason.parker‎, 09-09-2017 04:50 PM
    biostats, cancer, prediction
    • Replies: 2
    • Views: 169
    09-11-2017, 09:55 AM Go to last post
  7. what statistical test to choose (large smple size)

    Hi all, I need to perform a test which shows if there is a statistical difference between males and females in getting diagnosis. I believe I should...

    Started by bburugap‎, 09-09-2017 08:34 PM
    • Replies: 2
    • Views: 191
    09-10-2017, 09:48 AM Go to last post
  8. Chi square p value <0.01 but graph pad prompts not valid

    Hello all, i have used graph pad prism to calculate p- value. my contingency table contains some observed frequencies which are 0. my p-value has...

    Started by Tiya‎, 09-09-2017 12:52 PM
    • Replies: 1
    • Views: 133
    09-09-2017, 01:09 PM Go to last post
  9. Poll Poll: Similarity instead of differences in means b/w 2 groups

    Hi - long time lurker. First time poster. I'm hoping folks can provide guidance and opinions. I am looking at a small pilot study (n=16) of...

    Started by drtoddchang‎, 08-28-2017 12:16 AM
    equivalence, heart rate, paired, wilcoxon signed
    • Replies: 4
    • Views: 348
    08-28-2017, 03:33 PM Go to last post
  10. Is Chi-square appropriate for a single measurement variable with repeated measures?

    Hi! I am looking at how many burrows are occupied by a skink species at eight sites across a property. Counts of the number of occupied burrows...

    Started by RustyEcologist‎, 08-22-2017 11:54 PM
    • Replies: 2
    • Views: 296
    08-24-2017, 06:20 PM Go to last post
  11. One way ANOVA vs Kruskal Wallis

    Hi, I am comparing four groups (measurements of bone thickness and other bone parameters). The distributions are normal (Kolmogorov–Smirnov test)...

    Started by n.lu‎, 08-23-2017 05:04 AM
    kruskal wallis, nonparametric, one way anova, parametric
    • Replies: 1
    • Views: 212
    08-23-2017, 08:38 AM Go to last post
  12. Question Can I calculate the % of people positive for an outcome from an odds ratio?

    Hi, Thanks for looking at my question. Background I am doing a systematic reveiw and metanalysis, essentially on diagnostic test accuracy and...

    Started by SSSA‎, 08-18-2017 10:09 AM
    odds ratio
    • Replies: 8
    • Views: 337
    08-21-2017, 02:45 AM Go to last post
  13. Cox Regression with missing values

    Very grateful for any advice. I'm trying to perform Cox regression on a data set with multiple random missing values. SPSS is my go-to software,...

    Started by Rowena‎, 08-13-2017 04:36 AM
    cox regression, missing values, sas, spss
    • Replies: 5
    • Views: 336
    08-17-2017, 05:06 AM Go to last post
  14. Best scenario: unpaired or paired situation?

    I have a few questions, but first let me give you some necessary background of the experiment and the underlying questions. Basically, the design...

    Started by tleal‎, 08-15-2017 11:37 AM
    hypothesis testing, matched, paired, pairing, unpaired
    • Replies: 0
    • Views: 161
    08-15-2017, 11:37 AM Go to last post
  15. Freidman test with missing values?

    I have a set of data at four time points, but some subjects only two out of the four time points. Can I still use Friedman test for this in SPSS?

    Started by zhu‎, 08-15-2017 11:34 AM
    • Replies: 0
    • Views: 112
    08-15-2017, 11:34 AM Go to last post
  16. Propensity Score Matching

    Hi! I'm conducting a retrospective study in which we want to analyze time period of 60 days before occurence of a particular adverse event. To do...

    Started by joanna513‎, 08-09-2017 07:06 AM
    propensity score matching
    • Replies: 1
    • Views: 241
    08-09-2017, 08:56 AM Go to last post
  17. Poisson Standard Deviation

    Hi! Just a sanity check as I have to do a few computations for a report manually. Our indicator is defined in the following way: #...

    Started by jamesmartinn‎, 06-05-2017 10:03 AM
    • Replies: 6
    • Views: 815
    08-08-2017, 09:34 PM Go to last post
  18. Normal Approximation, Fisher's Exact Test, Relative Risk or Odds Ratio?

    A clinical trial is being planned, in which the primary outcome is binary (success/failure). There are two treatment groups (treatment/control). The...

    Started by WeeG‎, 06-17-2017 01:06 PM
    • Replies: 7
    • Views: 796
    08-08-2017, 09:33 PM Go to last post
  19. Help with correct statistical analysis?

    I am conducting an audit into vitamin D deficiency in children. I have the mean serum concentrations of vitamin D in specific areas (postcodes)...

    Started by MedStudent‎, 07-03-2017 05:54 PM
    • Replies: 5
    • Views: 499
    08-08-2017, 09:32 PM Go to last post
  20. Statistical significance

    Hi, I have the following problem and I would need some piece of advice to solve it: I have a group of 28 patients (17 survived, 11 died) and I...

    Started by Carcassonne‎, 07-10-2017 02:51 AM
    • Replies: 8
    • Views: 573
    08-08-2017, 09:31 PM Go to last post
  21. Critiquing a Network Meta-analysis: Interpreting inconsistency

    Hi all. I'm a non-statistician trying to critique a network meta-analysis on a group of migraine medications called triptans (PDF link). The...

    Started by networkMA‎, 07-18-2017 02:18 PM
    • Replies: 3
    • Views: 328
    08-08-2017, 09:30 PM Go to last post
  22. Exclamation STATA Logistic Regression Intepretation

    Hi, My dependent variable is goes to college coded 0=No and 1= Yes. I am not sure how STATA reads/ranks the dependent variable....thus I am not...

    Started by I_AM_KB‎, 08-03-2017 02:53 PM
    interpreting odds ratios, logistic regression, stata
    • Replies: 0
    • Views: 269
    08-03-2017, 02:53 PM Go to last post
  23. Sphericity with unequal sample sizes

    Hello, I want to do a repeated measures anova in R on a data set consisting of four treatments on subjects, over 4 weeks. However, in week 3 I am...

    Started by Wouterka‎, 07-30-2017 11:21 AM
    rstudio
    • Replies: 0
    • Views: 248
    07-30-2017, 11:21 AM Go to last post
  24. Question Need Appropriate Test for comparing a series of measurements from one bone to another

    My research involves taking measurements at 9 sections at different locations on the shaft of bones. I am having trouble determining which...

    Started by SierraS‎, 07-13-2017 11:58 PM
    bone, pair, series, test
    • Replies: 2
    • Views: 416
    07-23-2017, 08:41 PM Go to last post
  25. Online Biostatistics Course/Master's Degree

    Hi everyone, I'll be glad if someone could recommend me some online Biostatistics Course or Master's Degree for beginner. Thanks!

    Started by ovallecc‎, 07-20-2017 03:07 AM
    recommendation
    • Replies: 1
    • Views: 378
    07-20-2017, 04:23 AM Go to last post
  26. Patient-year Incidence rates comparisons and p value

    Dear all, I would like to statistically compare two incidence rates from two different groupes. I found the Incidence rate difference (IRD)...

    Started by didye‎, 07-19-2017 04:43 AM
    compare rates, incidence rate, ird
    • Replies: 0
    • Views: 256
    07-19-2017, 04:43 AM Go to last post
  27. Help with comparing disease death rates over time

    Hello everyone, I am working with a national mortality file and have pulled certain deaths for a particular disease and created crude rates by...

    Started by LAM_13‎, 07-17-2017 07:03 PM
    • Replies: 0
    • Views: 360
    07-17-2017, 07:03 PM Go to last post
  28. Software for NHANES Analysis

    Hello! I'm going to be using NHANES data for some of my research looking at dietary factors and health-related outcomes. I have a bit of exposure to...

    Started by mam326‎, 07-14-2017 04:25 PM
    nhanes
    • Replies: 0
    • Views: 313
    07-14-2017, 04:25 PM Go to last post
  29. Multi-level Meta-regression using random effect for treatment? [R pkg metafor]

    I am a biostatistician consulting on a meta-analysis of 16 studies each w/ 2 treatment arms. The main interest is in the effect of the variable...

    Started by chelbylu‎, 07-06-2017 03:45 AM
    hierarchical model, meta-regression, r metafor, random effects, treatment
    • Replies: 0
    • Views: 399
    07-06-2017, 03:45 AM Go to last post
  30. Help choosing right statistics

    The experiment consisted of testing the effect of several diets on the weight of fish. I want to check what groups differ from each other. There is...

    Started by Andre Barreto‎, 06-26-2017 02:58 PM
    • Replies: 2
    • Views: 502
    06-26-2017, 04:06 PM Go to last post
  31. sample size calculation for chi square test with more than 2 groups

    Greetings everybody I'm running a sample size estimation for a study that will use chi square test of association for the qualitative comparison of...

    Started by Bassam‎, 06-07-2017 06:23 PM
    • Replies: 4
    • Views: 926
    06-08-2017, 10:58 AM Go to last post
  32. test for cumulative analysis of outcomes over time in meta-analysis

    A systematic review and meta-analysis I am reading references having tested for chronological cumulative analysis for the effects of the outcomes...

    Started by Roundtoit‎, 06-02-2017 05:41 PM
    • Replies: 3
    • Views: 822
    06-04-2017, 03:02 PM Go to last post
  33. Simple question re retrospective study types

    Hi, Please could someone confirm that I'm using the correct terminology to describe two studies listed below. I think that they are both...

    Started by ConnemaraPony‎, 05-30-2017 01:31 PM
    • Replies: 2
    • Views: 982
    05-30-2017, 03:48 PM Go to last post
  34. Non Inferiority with a Historical Control

    Is it possible or valid to do a Non-Inferioirty Test againts a historical control. I should point out for the historical control all I have is a...

    Started by polc1410‎, 05-30-2017 04:09 AM
    • Replies: 1
    • Views: 560
    05-30-2017, 08:46 AM Go to last post
  35. Should I perform a PCA on my datas?

    Hi, I'm new to the statistic world. I have doubts about pca. I am performing the statistics of my study and I have a lot of data. I wonder if I can...

    Started by Clarissa‎, 05-26-2017 08:36 AM
    • Replies: 0
    • Views: 700
    05-26-2017, 08:36 AM Go to last post
  36. covariate for only clinical group

    HI I have tried to find an answer on the web but was not able, and will appreciate your help! I have a question regarding the use of a covariate in...

    Started by newbeeme‎, 05-21-2017 01:48 AM
    • Replies: 3
    • Views: 1,086
    05-22-2017, 09:28 AM Go to last post
  37. Absolute values or Log-transformed data

    I want to perform a non parametric test (mann-whitney) for my experiments that is briefly quantification of viral load (Real Time Polymerase chain...

    Started by julian_DE‎, 05-15-2017 01:06 AM
    • Replies: 3
    • Views: 950
    05-15-2017, 08:55 PM Go to last post
  38. Smile Mixed Model Analysis SPSS

    Hello All, I have a data set which I am trying to find out what is the best way to go about analyzing. I have been asking around and was advised...

    Started by quix09‎, 05-15-2017 08:24 AM
    • Replies: 0
    • Views: 702
    05-15-2017, 08:24 AM Go to last post
  39. Is Cochran's Q the right test for repeated measures with binary outcomes?

    Hi, I am trying to analyze a data set. The question we are looking at is whether the rate of a successful outcome and the risk of a...

    Started by Jennifer Kosty‎, 05-12-2017 12:15 PM
    • Replies: 0
    • Views: 618
    05-12-2017, 12:15 PM Go to last post
  40. Different proportions in different conditions?

    Hi, I am struggling with the proper way to analyze my data. I did some research in and out of this forum but could not find the answer to my...

    Started by Fanny-‎, 04-11-2017 08:06 AM
    • Replies: 3
    • Views: 1,484
    05-07-2017, 03:06 AM Go to last post
  41. GLM with non-linear predictor

    Hi, I am analyzing a dataset looking at procedural skill development. The data itself is binomial, whether or not a procedure was successful. When...

    Started by amw2320‎, 05-06-2017 11:02 PM
    • Replies: 0
    • Views: 699
    05-06-2017, 11:02 PM Go to last post
  42. Contingency tables with proportions only

    Hi, I have a 3x2 contingency table, which contains the observed and expected allele frequencies from a hypothetical population and I'd like to test...

    Started by Acather96‎, 05-04-2017 02:23 PM
    • Replies: 8
    • Views: 1,125
    05-04-2017, 05:59 PM Go to last post
  43. Post Chi-square goodness of fit test

    Hi all, I'm currently conducting research at a radiology department. The setup of our research is that we let 2 radiologists indicate their...

    Started by MaxTalksStats‎, 05-01-2017 03:29 AM
    • Replies: 1
    • Views: 862
    05-01-2017, 04:23 AM Go to last post
  44. Association/ correlation binary and continuous data non-normal distribution

    Hi, I want to perform an association analysis between a binary (dichotomous?) variable and continuous variable. The binary variable is whether...

    Started by Hannah212‎, 04-27-2017 03:37 AM
    binary, continuous, correlation analysis, point-biserial
    • Replies: 5
    • Views: 922
    04-27-2017, 02:59 PM Go to last post
  45. Wink Antibiogram

    greetings :yup: im doing a documentary review of the Clinical Profile and Antibiogram Pattern of Patients With Diabetic Foot Ulcers. Problem is, I...

    Started by otepmeimban‎, 04-27-2017 12:44 PM
    • Replies: 1
    • Views: 817
    04-27-2017, 01:02 PM Go to last post
  46. what statistical test to choose

    Hi all, I am working on a similar kind of project as this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313376/ For table 2, what are the...

    Started by bburugap‎, 04-24-2017 02:15 PM
    • Replies: 0
    • Views: 875
    04-24-2017, 02:15 PM Go to last post
  47. Can i use one sample t-test?

    Hi all Currently im doing a research to see how effective my results as compared to the mean value and standard deviation of previous study. ...

    Started by hnw‎, 04-20-2017 04:41 AM
    one sample t test
    • Replies: 2
    • Views: 1,146
    04-20-2017, 08:16 AM Go to last post
  48. Question reference interval determination

    Hi all, I was wondering if I could ask for some help from some more statistically inclined persons than myself. We are trying to determine a...

    Started by romes‎, 03-25-2017 10:23 AM
    biostatistics, reference interval
    • Replies: 1
    • Views: 1,327
    04-16-2017, 08:32 AM Go to last post
  49. Problem with normalization and - proteomics analysis (LC-MS)

    Hi folks, I am working with proteomics data, containing mainly LC-MS and NMRI analysis. Firstly, I must normalise data to give valuable compound...

    Started by robertp‎, 04-15-2017 11:04 AM
    biostatistics, data analysis, nmri, normalization, proteomics
    • Replies: 0
    • Views: 656
    04-15-2017, 11:04 AM Go to last post
  50. Bias Question

    My statistics teacher and I are at a disagreement with an answer to one of his questions and I was wondering if you all could help me out. The...

    Started by jimsam321‎, 04-12-2017 04:55 PM
    • Replies: 14
    • Views: 1,102
    04-13-2017, 09:29 AM Go to last post
  51. Question Comparing groups - Should I do hypotesis testing on raw counts or percentage values?

    Hi, first post here, and I really hope you can help me with this. I'm measuring the number of cells labelled with two markers (let's call them A...

    Started by sgomes‎, 04-10-2017 10:37 AM
    • Replies: 3
    • Views: 835
    04-10-2017, 04:57 PM Go to last post
  52. Chi Square test (not significant when comparing across 4 groups but changes with 2)

    Hi all, I was conducting a chi-square + fisher test and ran across a problem: I am using a chi square to test whether or not there is an...

    Started by Nives_ES‎, 04-07-2017 11:45 AM
    • Replies: 2
    • Views: 962
    04-07-2017, 02:08 PM Go to last post
  53. Statistical help (not independent samples)

    Hello all, I need some help in understanding what statistical test to use when I have 3 groups and the groups are not independent of each other...

    Started by bburugap‎, 04-01-2017 02:40 PM
    • Replies: 2
    • Views: 1,009
    04-05-2017, 04:04 PM Go to last post
  54. How to do age standardization for morbidity study (2 populations)

    Good day all, I have a question in regards to age standardization. My study is on morbidity(disease) and I have 2 populations. The populations are...

    Started by happiness17‎, 04-04-2017 04:47 AM
    • Replies: 0
    • Views: 843
    04-04-2017, 04:47 AM Go to last post
  55. Unhappy Which test for equivalency?

    I have two machines A & B. 5 patients. I calculate the elasticity of their skin with the two different machines. This gives me two numbers per...

    Started by yolo123‎, 04-01-2017 07:00 PM
    • Replies: 6
    • Views: 1,180
    04-02-2017, 04:15 PM Go to last post
  56. PCA questions?

    Hi there, I am a bit new to statistics and have a few questions. I am currently doing my dissertation on the consistent and variable...

    Started by Callum94‎, 03-29-2017 12:59 PM
    • Replies: 3
    • Views: 1,280
    03-29-2017, 06:36 PM Go to last post
  57. Predicting outcome with multiple groups

    Hi everyone, I'm currently working with 3 different groups (3 disease populations) and I would like to predict which of the three groups they fall...

    Started by Eric2014‎, 03-28-2017 12:14 PM
    groups, logistic, prediction, regression
    • Replies: 4
    • Views: 974
    03-28-2017, 03:45 PM Go to last post
  58. Finding data given sample mean and variance

    Hello, I have a problem, I am given the sample size, mean, variance, and I know it is normally distributed. The question states that 160...

    Started by dorothy8‎, 03-26-2017 06:56 PM
    • Replies: 2
    • Views: 1,124
    03-27-2017, 09:56 PM Go to last post
  59. am i overadjusting?

    might sound silly but for my research topic I am looking into insulin resistance (IR) and dietary factors. We are measuring IR by the use of...

    Started by jkerr1‎, 03-27-2017 04:56 AM
    • Replies: 1
    • Views: 876
    03-27-2017, 10:23 AM Go to last post
  60. Confidence interval question

    Fr a sample of 100 hypertensive patients, we find that a 95% confidence interval of systolic BP to be . What statement is FALSE? A- if a drug is...

    Started by dorothy8‎, 03-26-2017 05:53 PM
    • Replies: 1
    • Views: 880
    03-27-2017, 02:20 AM Go to last post

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