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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Question Can I calculate the % of people positive for an outcome from an odds ratio?

    Hi, Thanks for looking at my question. Background I am doing a systematic reveiw and metanalysis, essentially on diagnostic test accuracy and...

    Started by SSSA‎, 08-18-2017 10:09 AM
    odds ratio
    • Replies: 5
    • Views: 143
    Today, 09:23 AM Go to last post
  2. Cox Regression with missing values

    Very grateful for any advice. I'm trying to perform Cox regression on a data set with multiple random missing values. SPSS is my go-to software,...

    Started by Rowena‎, 08-13-2017 04:36 AM
    cox regression, missing values, sas, spss
    • Replies: 5
    • Views: 230
    08-17-2017, 05:06 AM Go to last post
  3. Best scenario: unpaired or paired situation?

    I have a few questions, but first let me give you some necessary background of the experiment and the underlying questions. Basically, the design...

    Started by tleal‎, 08-15-2017 11:37 AM
    hypothesis testing, matched, paired, pairing, unpaired
    • Replies: 0
    • Views: 92
    08-15-2017, 11:37 AM Go to last post
  4. Freidman test with missing values?

    I have a set of data at four time points, but some subjects only two out of the four time points. Can I still use Friedman test for this in SPSS?

    Started by zhu‎, 08-15-2017 11:34 AM
    • Replies: 0
    • Views: 57
    08-15-2017, 11:34 AM Go to last post
  5. Propensity Score Matching

    Hi! I'm conducting a retrospective study in which we want to analyze time period of 60 days before occurence of a particular adverse event. To do...

    Started by joanna513‎, 08-09-2017 07:06 AM
    propensity score matching
    • Replies: 1
    • Views: 160
    08-09-2017, 08:56 AM Go to last post
  6. Poisson Standard Deviation

    Hi! Just a sanity check as I have to do a few computations for a report manually. Our indicator is defined in the following way: #...

    Started by jamesmartinn‎, 06-05-2017 10:03 AM
    • Replies: 6
    • Views: 643
    08-08-2017, 09:34 PM Go to last post
  7. Normal Approximation, Fisher's Exact Test, Relative Risk or Odds Ratio?

    A clinical trial is being planned, in which the primary outcome is binary (success/failure). There are two treatment groups (treatment/control). The...

    Started by WeeG‎, 06-17-2017 01:06 PM
    • Replies: 7
    • Views: 643
    08-08-2017, 09:33 PM Go to last post
  8. Help with correct statistical analysis?

    I am conducting an audit into vitamin D deficiency in children. I have the mean serum concentrations of vitamin D in specific areas (postcodes)...

    Started by MedStudent‎, 07-03-2017 05:54 PM
    • Replies: 5
    • Views: 356
    08-08-2017, 09:32 PM Go to last post
  9. Statistical significance

    Hi, I have the following problem and I would need some piece of advice to solve it: I have a group of 28 patients (17 survived, 11 died) and I...

    Started by Carcassonne‎, 07-10-2017 02:51 AM
    • Replies: 8
    • Views: 433
    08-08-2017, 09:31 PM Go to last post
  10. Critiquing a Network Meta-analysis: Interpreting inconsistency

    Hi all. I'm a non-statistician trying to critique a network meta-analysis on a group of migraine medications called triptans (PDF link). The...

    Started by networkMA‎, 07-18-2017 02:18 PM
    • Replies: 3
    • Views: 257
    08-08-2017, 09:30 PM Go to last post
  11. Exclamation STATA Logistic Regression Intepretation

    Hi, My dependent variable is goes to college coded 0=No and 1= Yes. I am not sure how STATA reads/ranks the dependent variable....thus I am not...

    Started by I_AM_KB‎, 08-03-2017 02:53 PM
    interpreting odds ratios, logistic regression, stata
    • Replies: 0
    • Views: 209
    08-03-2017, 02:53 PM Go to last post
  12. Sphericity with unequal sample sizes

    Hello, I want to do a repeated measures anova in R on a data set consisting of four treatments on subjects, over 4 weeks. However, in week 3 I am...

    Started by Wouterka‎, 07-30-2017 11:21 AM
    rstudio
    • Replies: 0
    • Views: 190
    07-30-2017, 11:21 AM Go to last post
  13. Question Need Appropriate Test for comparing a series of measurements from one bone to another

    My research involves taking measurements at 9 sections at different locations on the shaft of bones. I am having trouble determining which...

    Started by SierraS‎, 07-13-2017 11:58 PM
    bone, pair, series, test
    • Replies: 2
    • Views: 342
    07-23-2017, 08:41 PM Go to last post
  14. Online Biostatistics Course/Master's Degree

    Hi everyone, I'll be glad if someone could recommend me some online Biostatistics Course or Master's Degree for beginner. Thanks!

    Started by ovallecc‎, 07-20-2017 03:07 AM
    recommendation
    • Replies: 1
    • Views: 284
    07-20-2017, 04:23 AM Go to last post
  15. Patient-year Incidence rates comparisons and p value

    Dear all, I would like to statistically compare two incidence rates from two different groupes. I found the Incidence rate difference (IRD)...

    Started by didye‎, 07-19-2017 04:43 AM
    compare rates, incidence rate, ird
    • Replies: 0
    • Views: 167
    07-19-2017, 04:43 AM Go to last post
  16. Help with comparing disease death rates over time

    Hello everyone, I am working with a national mortality file and have pulled certain deaths for a particular disease and created crude rates by...

    Started by LAM_13‎, 07-17-2017 07:03 PM
    • Replies: 0
    • Views: 201
    07-17-2017, 07:03 PM Go to last post
  17. Software for NHANES Analysis

    Hello! I'm going to be using NHANES data for some of my research looking at dietary factors and health-related outcomes. I have a bit of exposure to...

    Started by mam326‎, 07-14-2017 04:25 PM
    nhanes
    • Replies: 0
    • Views: 242
    07-14-2017, 04:25 PM Go to last post
  18. Multi-level Meta-regression using random effect for treatment? [R pkg metafor]

    I am a biostatistician consulting on a meta-analysis of 16 studies each w/ 2 treatment arms. The main interest is in the effect of the variable...

    Started by chelbylu‎, 07-06-2017 03:45 AM
    hierarchical model, meta-regression, r metafor, random effects, treatment
    • Replies: 0
    • Views: 312
    07-06-2017, 03:45 AM Go to last post
  19. Help choosing right statistics

    The experiment consisted of testing the effect of several diets on the weight of fish. I want to check what groups differ from each other. There is...

    Started by Andre Barreto‎, 06-26-2017 02:58 PM
    • Replies: 2
    • Views: 385
    06-26-2017, 04:06 PM Go to last post
  20. sample size calculation for chi square test with more than 2 groups

    Greetings everybody I'm running a sample size estimation for a study that will use chi square test of association for the qualitative comparison of...

    Started by Bassam‎, 06-07-2017 06:23 PM
    • Replies: 4
    • Views: 726
    06-08-2017, 10:58 AM Go to last post
  21. test for cumulative analysis of outcomes over time in meta-analysis

    A systematic review and meta-analysis I am reading references having tested for chronological cumulative analysis for the effects of the outcomes...

    Started by Roundtoit‎, 06-02-2017 05:41 PM
    • Replies: 3
    • Views: 607
    06-04-2017, 03:02 PM Go to last post
  22. Simple question re retrospective study types

    Hi, Please could someone confirm that I'm using the correct terminology to describe two studies listed below. I think that they are both...

    Started by ConnemaraPony‎, 05-30-2017 01:31 PM
    • Replies: 2
    • Views: 712
    05-30-2017, 03:48 PM Go to last post
  23. Non Inferiority with a Historical Control

    Is it possible or valid to do a Non-Inferioirty Test againts a historical control. I should point out for the historical control all I have is a...

    Started by polc1410‎, 05-30-2017 04:09 AM
    • Replies: 1
    • Views: 404
    05-30-2017, 08:46 AM Go to last post
  24. Should I perform a PCA on my datas?

    Hi, I'm new to the statistic world. I have doubts about pca. I am performing the statistics of my study and I have a lot of data. I wonder if I can...

    Started by Clarissa‎, 05-26-2017 08:36 AM
    • Replies: 0
    • Views: 537
    05-26-2017, 08:36 AM Go to last post
  25. covariate for only clinical group

    HI I have tried to find an answer on the web but was not able, and will appreciate your help! I have a question regarding the use of a covariate in...

    Started by newbeeme‎, 05-21-2017 01:48 AM
    • Replies: 3
    • Views: 785
    05-22-2017, 09:28 AM Go to last post
  26. Absolute values or Log-transformed data

    I want to perform a non parametric test (mann-whitney) for my experiments that is briefly quantification of viral load (Real Time Polymerase chain...

    Started by julian_DE‎, 05-15-2017 01:06 AM
    • Replies: 3
    • Views: 748
    05-15-2017, 08:55 PM Go to last post
  27. Smile Mixed Model Analysis SPSS

    Hello All, I have a data set which I am trying to find out what is the best way to go about analyzing. I have been asking around and was advised...

    Started by quix09‎, 05-15-2017 08:24 AM
    • Replies: 0
    • Views: 521
    05-15-2017, 08:24 AM Go to last post
  28. Is Cochran's Q the right test for repeated measures with binary outcomes?

    Hi, I am trying to analyze a data set. The question we are looking at is whether the rate of a successful outcome and the risk of a...

    Started by Jennifer Kosty‎, 05-12-2017 12:15 PM
    • Replies: 0
    • Views: 488
    05-12-2017, 12:15 PM Go to last post
  29. Different proportions in different conditions?

    Hi, I am struggling with the proper way to analyze my data. I did some research in and out of this forum but could not find the answer to my...

    Started by Fanny-‎, 04-11-2017 08:06 AM
    • Replies: 3
    • Views: 1,170
    05-07-2017, 03:06 AM Go to last post
  30. GLM with non-linear predictor

    Hi, I am analyzing a dataset looking at procedural skill development. The data itself is binomial, whether or not a procedure was successful. When...

    Started by amw2320‎, 05-06-2017 11:02 PM
    • Replies: 0
    • Views: 569
    05-06-2017, 11:02 PM Go to last post
  31. Contingency tables with proportions only

    Hi, I have a 3x2 contingency table, which contains the observed and expected allele frequencies from a hypothetical population and I'd like to test...

    Started by Acather96‎, 05-04-2017 02:23 PM
    • Replies: 8
    • Views: 781
    05-04-2017, 05:59 PM Go to last post
  32. Post Chi-square goodness of fit test

    Hi all, I'm currently conducting research at a radiology department. The setup of our research is that we let 2 radiologists indicate their...

    Started by MaxTalksStats‎, 05-01-2017 03:29 AM
    • Replies: 1
    • Views: 702
    05-01-2017, 04:23 AM Go to last post
  33. Association/ correlation binary and continuous data non-normal distribution

    Hi, I want to perform an association analysis between a binary (dichotomous?) variable and continuous variable. The binary variable is whether...

    Started by Hannah212‎, 04-27-2017 03:37 AM
    binary, continuous, correlation analysis, point-biserial
    • Replies: 5
    • Views: 756
    04-27-2017, 02:59 PM Go to last post
  34. Wink Antibiogram

    greetings :yup: im doing a documentary review of the Clinical Profile and Antibiogram Pattern of Patients With Diabetic Foot Ulcers. Problem is, I...

    Started by otepmeimban‎, 04-27-2017 12:44 PM
    • Replies: 1
    • Views: 607
    04-27-2017, 01:02 PM Go to last post
  35. what statistical test to choose

    Hi all, I am working on a similar kind of project as this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313376/ For table 2, what are the...

    Started by bburugap‎, 04-24-2017 02:15 PM
    • Replies: 0
    • Views: 667
    04-24-2017, 02:15 PM Go to last post
  36. Can i use one sample t-test?

    Hi all Currently im doing a research to see how effective my results as compared to the mean value and standard deviation of previous study. ...

    Started by hnw‎, 04-20-2017 04:41 AM
    one sample t test
    • Replies: 2
    • Views: 896
    04-20-2017, 08:16 AM Go to last post
  37. Question reference interval determination

    Hi all, I was wondering if I could ask for some help from some more statistically inclined persons than myself. We are trying to determine a...

    Started by romes‎, 03-25-2017 10:23 AM
    biostatistics, reference interval
    • Replies: 1
    • Views: 1,017
    04-16-2017, 08:32 AM Go to last post
  38. Problem with normalization and - proteomics analysis (LC-MS)

    Hi folks, I am working with proteomics data, containing mainly LC-MS and NMRI analysis. Firstly, I must normalise data to give valuable compound...

    Started by robertp‎, 04-15-2017 11:04 AM
    biostatistics, data analysis, nmri, normalization, proteomics
    • Replies: 0
    • Views: 503
    04-15-2017, 11:04 AM Go to last post
  39. Bias Question

    My statistics teacher and I are at a disagreement with an answer to one of his questions and I was wondering if you all could help me out. The...

    Started by jimsam321‎, 04-12-2017 04:55 PM
    • Replies: 14
    • Views: 909
    04-13-2017, 09:29 AM Go to last post
  40. Question Comparing groups - Should I do hypotesis testing on raw counts or percentage values?

    Hi, first post here, and I really hope you can help me with this. I'm measuring the number of cells labelled with two markers (let's call them A...

    Started by sgomes‎, 04-10-2017 10:37 AM
    • Replies: 3
    • Views: 690
    04-10-2017, 04:57 PM Go to last post
  41. Chi Square test (not significant when comparing across 4 groups but changes with 2)

    Hi all, I was conducting a chi-square + fisher test and ran across a problem: I am using a chi square to test whether or not there is an...

    Started by Nives_ES‎, 04-07-2017 11:45 AM
    • Replies: 2
    • Views: 783
    04-07-2017, 02:08 PM Go to last post
  42. Statistical help (not independent samples)

    Hello all, I need some help in understanding what statistical test to use when I have 3 groups and the groups are not independent of each other...

    Started by bburugap‎, 04-01-2017 02:40 PM
    • Replies: 2
    • Views: 804
    04-05-2017, 04:04 PM Go to last post
  43. How to do age standardization for morbidity study (2 populations)

    Good day all, I have a question in regards to age standardization. My study is on morbidity(disease) and I have 2 populations. The populations are...

    Started by happiness17‎, 04-04-2017 04:47 AM
    • Replies: 0
    • Views: 661
    04-04-2017, 04:47 AM Go to last post
  44. Unhappy Which test for equivalency?

    I have two machines A & B. 5 patients. I calculate the elasticity of their skin with the two different machines. This gives me two numbers per...

    Started by yolo123‎, 04-01-2017 07:00 PM
    • Replies: 6
    • Views: 927
    04-02-2017, 04:15 PM Go to last post
  45. PCA questions?

    Hi there, I am a bit new to statistics and have a few questions. I am currently doing my dissertation on the consistent and variable...

    Started by Callum94‎, 03-29-2017 12:59 PM
    • Replies: 3
    • Views: 1,064
    03-29-2017, 06:36 PM Go to last post
  46. Predicting outcome with multiple groups

    Hi everyone, I'm currently working with 3 different groups (3 disease populations) and I would like to predict which of the three groups they fall...

    Started by Eric2014‎, 03-28-2017 12:14 PM
    groups, logistic, prediction, regression
    • Replies: 4
    • Views: 802
    03-28-2017, 03:45 PM Go to last post
  47. Finding data given sample mean and variance

    Hello, I have a problem, I am given the sample size, mean, variance, and I know it is normally distributed. The question states that 160...

    Started by dorothy8‎, 03-26-2017 06:56 PM
    • Replies: 2
    • Views: 817
    03-27-2017, 09:56 PM Go to last post
  48. am i overadjusting?

    might sound silly but for my research topic I am looking into insulin resistance (IR) and dietary factors. We are measuring IR by the use of...

    Started by jkerr1‎, 03-27-2017 04:56 AM
    • Replies: 1
    • Views: 688
    03-27-2017, 10:23 AM Go to last post
  49. Confidence interval question

    Fr a sample of 100 hypertensive patients, we find that a 95% confidence interval of systolic BP to be . What statement is FALSE? A- if a drug is...

    Started by dorothy8‎, 03-26-2017 05:53 PM
    • Replies: 1
    • Views: 697
    03-27-2017, 02:20 AM Go to last post
  50. Pre and post comparison for nonparametric unpaired sample

    Hi. I am not sure how to compare the results from the following study. Number of wrong orders out of total orders placed every day for 60 days as...

    Started by anupamsule‎, 03-22-2017 09:01 PM
    • Replies: 2
    • Views: 1,084
    03-24-2017, 07:04 AM Go to last post
  51. Dealing with Log(0)

    Dear all, Iíve been stuck for quite some time with a problem that relates to use of log-scale with values that equal zero. My data comes from an...

    Started by ritmaniac‎, 03-21-2017 07:21 AM
    anova, linear regression, logarithmic
    • Replies: 2
    • Views: 1,328
    03-21-2017, 04:22 PM Go to last post
  52. Sample size calculation for 1:2 matched case-control study

    Hi, I have a matched case-control study with 12 cases and two controls for each case. Evaluating our findings, I want to calculate what our sample...

    Started by teapot‎, 03-08-2017 02:22 PM
    • Replies: 7
    • Views: 1,634
    03-17-2017, 08:59 AM Go to last post
  53. stratified log-rank test and proportional hazards

    Does stratified log-rank test overcome problem of violation of proportional hazards? I encountered a randomized controlled study of a new drug...

    Started by Markica85‎, 03-16-2017 04:53 AM
    • Replies: 0
    • Views: 964
    03-16-2017, 04:53 AM Go to last post
  54. Regarding Maximum Percent different

    Dear all, Could you please explain what maximum percent different for continues vital DiaBP data. How to calculate this? Could you any one...

    Started by Statvijay‎, 03-14-2017 07:08 AM
    • Replies: 0
    • Views: 739
    03-14-2017, 07:08 AM Go to last post
  55. Survival Analysis - Time to utilization of medical services

    Hi all, I work in the medical field and Iím looking into using survival analysis calculate time to utilization of medical services, that is, once...

    Started by avbraga‎, 03-10-2017 04:35 PM
    • Replies: 6
    • Views: 1,226
    03-13-2017, 06:07 PM Go to last post
  56. vision in eyes at different times

    Hi everyone, New to the forum and am seeking a bit of guidance as to how to compare vision (visual acuity) between eyes. So I am trying to...

    Started by jksgoh‎, 03-11-2017 02:44 AM
    • Replies: 1
    • Views: 811
    03-13-2017, 02:42 PM Go to last post
  57. Which statistical tests are appropriate: Group means before and after treatment

    I am trying to find out what statistical tests to run on a set of aggregate data (no individual data) on 3 different groups, variables are summarized...

    Started by PamelaF‎, 03-07-2017 04:17 AM
    • Replies: 1
    • Views: 1,194
    03-09-2017, 04:31 PM Go to last post
  58. Adjustment for correlated data in meta-anlaysis

    Hi, I'm completing a systematic review and performing meta-anlaysis forest plots. The research question related to the finding of risk factors for...

    Started by Ainslie‎, 03-08-2017 12:47 AM
    adjustment, correlated data, meta-analysis
    • Replies: 2
    • Views: 1,159
    03-08-2017, 11:07 AM Go to last post
  59. standard deviation greater than variance, is this ok?

    I am putting together some audit results and it was suggested I present them as mean +/- SD. However there is a significant variance in the results....

    Started by Roundtoit‎, 03-07-2017 05:44 PM
    • Replies: 7
    • Views: 2,327
    03-08-2017, 04:23 AM Go to last post
  60. Comparing diagnostic tests - graphically demonstration

    Hi, This is very basic but really struggling to find the correct terminology to find out what I want to do. I have collected data on two methods...

    Started by k093‎, 03-07-2017 07:17 PM
    • Replies: 0
    • Views: 878
    03-07-2017, 07:17 PM Go to last post

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