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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. Nonparametric data analysis

    I'm asking for advice. Topic of my research is brain iron accumulation. My task is the next . I have one dependent variable that is cathegorical and...

    Started by Mykola‎, 11-13-2017 03:24 PM
    2 Pages
    1 2
    confidence interval, corrections, logit, nonparametric, odds ratio., probability
    • Replies: 19
    • Views: 303
    Yesterday, 04:25 PM Go to last post
  2. Post evaluating performance

    Hi all: We've run up against a bit of a difficult scenario and we're looking for input on how to proceed. I will give some background on our data...

    Started by jamesmartinn‎, 11-16-2017 08:41 AM
    • Replies: 3
    • Views: 98
    Yesterday, 10:27 AM Go to last post
  3. Average standard deviation?

    Hi Everyone, Sorry if a similar question has been asked before. I didn't see a thread focused on my particular query. I have a large dataset of...

    Started by peptideguy‎, 11-15-2017 03:04 PM
    • Replies: 0
    • Views: 52
    11-15-2017, 03:04 PM Go to last post
  4. Question about meta-analysis

    Hello! I'm new here and I'm not a statistician but I would appreciate your inputs. Is it possible to make a meta-analysis investigating results...

    Started by termsndconditions‎, 11-07-2017 07:24 AM
    • Replies: 8
    • Views: 285
    11-10-2017, 10:33 AM Go to last post
  5. Statistical test for annual crude mortality trend (3 years data=3 data points)

    Help, I have the crude mortality figures for 2015, 2016, 2017 and would like to know if the figure for 2017 is statistically different. The...

    Started by JNelson‎, 11-08-2017 10:05 PM
    crude mortality, trend analysis
    • Replies: 1
    • Views: 104
    11-09-2017, 07:15 AM Go to last post
  6. What statistical test should I use?

    Hello, I am currently working on my thesis proposal and am having to state the proposed methods of my data analysis. I am focusing on two aims: 1)...

    Started by Victoria447‎, 11-06-2017 01:52 AM
    cross sectional, longitudinal, regression analysis, thesis
    • Replies: 1
    • Views: 172
    11-07-2017, 02:42 AM Go to last post
  7. Correlation between Platelet Count and Mean Platelet Volume

    I have attached my statistical analysis in this thread. It is about correlation between platelet count and mean platelet volume. I am conducting a...

    Started by IceFeast‎, 11-02-2017 02:37 AM
    • Replies: 0
    • Views: 170
    11-02-2017, 02:37 AM Go to last post
  8. P-Trend, what does it mean and how being calculated?

    Hello all :) I need your help... I am trying to make analysis based on a similar paper, and I can't understand the statistical method to be...

    Started by Yankel‎, 10-28-2017 12:29 PM
    • Replies: 0
    • Views: 231
    10-28-2017, 12:29 PM Go to last post
  9. [SPSS - Mixed Models] Repeated measurements data from randomised controlled trial

    I am analyzing data from a randomized clinical trial, with 2 intervention groups (placebo and intervention) and repeated measurements over time. I am...

    Started by Flightpete‎, 10-05-2017 11:25 AM
    control for, mixed effects model, randomized control trials, spss
    • Replies: 3
    • Views: 344
    10-22-2017, 05:59 AM Go to last post
  10. Means are not different but significant

    Hi. I have a query, generated from PrediXcan analysis but more related to statistics. I have the two means of predicted expression values for...

    Started by aqas‎, 10-20-2017 08:27 AM
    means difference, pvalues, significant
    • Replies: 1
    • Views: 353
    10-20-2017, 08:35 AM Go to last post
  11. Question Multiple t-tests vs ANOVA with Dunnett's post-hoc test

    Hello, I am bit confused about the use of multiple t-tests vs ANOVA with Dunnett's post-hoc test (on normally distributed data). Let's take the...

    Started by Biochemist‎, 10-14-2017 07:46 AM
    • Replies: 2
    • Views: 300
    10-14-2017, 12:18 PM Go to last post
  12. Retrospective chart review subject selection: case vs. control

    I did retrospective chart review on 240 subjects from my previous institute. THe study was on sedation required for bronchoscopy. The procedure used...

    Started by dr_pritish‎, 10-14-2017 10:37 AM
    chart review
    • Replies: 0
    • Views: 150
    10-14-2017, 10:37 AM Go to last post
  13. RCT: estimation of total sample size knowing only the percentage of occurrence

    Dear all, I was asked to estimate the minimum sample size to set up a RCT comparing a standard dose technique to detect recurrence of disease vs...

    Started by MDaniele‎, 10-12-2017 04:31 AM
    estimate, noninferiority, rct, sample size, trial
    • Replies: 0
    • Views: 137
    10-12-2017, 04:31 AM Go to last post
  14. Triangulating multiple data sources of prescription information

    I am currently working on a retrospective database study assessing the real-world effectiveness of a medication. I am faced with a few challenges. I...

    Started by vpmwar‎, 10-06-2017 11:59 AM
    agreement, cohens's kappa, correlation, triangulation
    • Replies: 0
    • Views: 193
    10-06-2017, 11:59 AM Go to last post
  15. Comparing the effectiveness of an intervention in two groups?

    Hi Everyone, I'm stuck trying to find a way to compare whether or not a given intervention has a greater effect in one group (Kids < 5) than...

    Started by jpgordon‎, 10-03-2017 10:29 PM
    • Replies: 1
    • Views: 172
    10-04-2017, 08:01 AM Go to last post
  16. Looking for a test to find if there is a relationship between 2 groups

    Hi all, I have a data set of two frequencies, one is the frequency of air temperature and the second is the frequency that an activity occurs at...

    Started by spulak‎, 10-02-2017 12:07 PM
    • Replies: 2
    • Views: 175
    10-02-2017, 03:37 PM Go to last post
  17. Block design anova

    I have a question about what the most appropriate anova design is for my data. I am posting here because I cannot seem to get the search function to...

    Started by vanguard605‎, 09-11-2017 03:52 PM
    anova, block design, community ecology
    • Replies: 2
    • Views: 435
    09-29-2017, 08:35 AM Go to last post
  18. Using logistic regression to compute age-adjusted rates

    Dear All, Would anybody please give me a breakdown no how to compute "age-adjusted proportions" based on the logistic regression coefficients? ...

    Started by Raok‎, 09-15-2017 06:53 AM
    • Replies: 4
    • Views: 588
    09-22-2017, 10:02 AM Go to last post
  19. Interpreting significance based on confidence interval

    Hi Everyone, Could some of you help to interpret my results based on p values and confidence intervals? A little bit of background: I am trying to...

    Started by julian_DE‎, 09-21-2017 07:48 AM
    • Replies: 3
    • Views: 330
    09-22-2017, 05:04 AM Go to last post
  20. Repeated measures with varying count between group

    I'll explain my problem a bit: I have two groups S(story) and P(picture). Each is composed of the same 48 subjects. My endpoint is a 'score' on an...

    Started by qjuice‎, 09-18-2017 06:46 PM
    • Replies: 5
    • Views: 447
    09-20-2017, 05:05 PM Go to last post
  21. Switch of distribution during observation period (Scratch Assay)

    Dear Stats-Talkers, I performed several Scratch Assays (its an experiment where cells close a cell-free gap over time, see also attached file I)...

    Started by Peters‎, 09-12-2017 04:00 AM
    • Replies: 0
    • Views: 292
    09-12-2017, 04:00 AM Go to last post
  22. Modeling and predicting pathology from multivariate clinical data

    Hello, I have a clinical data set that consists of 5 clinical measurements on thousands of tissue samples. Furthermore, each sample has a pathology...

    Started by jason.parker‎, 09-09-2017 04:50 PM
    biostats, cancer, prediction
    • Replies: 2
    • Views: 252
    09-11-2017, 09:55 AM Go to last post
  23. what statistical test to choose (large smple size)

    Hi all, I need to perform a test which shows if there is a statistical difference between males and females in getting diagnosis. I believe I should...

    Started by bburugap‎, 09-09-2017 08:34 PM
    • Replies: 2
    • Views: 324
    09-10-2017, 09:48 AM Go to last post
  24. Chi square p value <0.01 but graph pad prompts not valid

    Hello all, i have used graph pad prism to calculate p- value. my contingency table contains some observed frequencies which are 0. my p-value has...

    Started by Tiya‎, 09-09-2017 12:52 PM
    • Replies: 1
    • Views: 218
    09-09-2017, 01:09 PM Go to last post
  25. Poll Poll: Similarity instead of differences in means b/w 2 groups

    Hi - long time lurker. First time poster. I'm hoping folks can provide guidance and opinions. I am looking at a small pilot study (n=16) of...

    Started by drtoddchang‎, 08-28-2017 12:16 AM
    equivalence, heart rate, paired, wilcoxon signed
    • Replies: 4
    • Views: 598
    08-28-2017, 03:33 PM Go to last post
  26. Is Chi-square appropriate for a single measurement variable with repeated measures?

    Hi! I am looking at how many burrows are occupied by a skink species at eight sites across a property. Counts of the number of occupied burrows...

    Started by RustyEcologist‎, 08-22-2017 11:54 PM
    • Replies: 2
    • Views: 374
    08-24-2017, 06:20 PM Go to last post
  27. One way ANOVA vs Kruskal Wallis

    Hi, I am comparing four groups (measurements of bone thickness and other bone parameters). The distributions are normal (Kolmogorov–Smirnov test)...

    Started by n.lu‎, 08-23-2017 05:04 AM
    kruskal wallis, nonparametric, one way anova, parametric
    • Replies: 1
    • Views: 465
    08-23-2017, 08:38 AM Go to last post
  28. Question Can I calculate the % of people positive for an outcome from an odds ratio?

    Hi, Thanks for looking at my question. Background I am doing a systematic reveiw and metanalysis, essentially on diagnostic test accuracy and...

    Started by SSSA‎, 08-18-2017 10:09 AM
    odds ratio
    • Replies: 8
    • Views: 436
    08-21-2017, 02:45 AM Go to last post
  29. Cox Regression with missing values

    Very grateful for any advice. I'm trying to perform Cox regression on a data set with multiple random missing values. SPSS is my go-to software,...

    Started by Rowena‎, 08-13-2017 04:36 AM
    cox regression, missing values, sas, spss
    • Replies: 5
    • Views: 564
    08-17-2017, 05:06 AM Go to last post
  30. Best scenario: unpaired or paired situation?

    I have a few questions, but first let me give you some necessary background of the experiment and the underlying questions. Basically, the design...

    Started by tleal‎, 08-15-2017 11:37 AM
    hypothesis testing, matched, paired, pairing, unpaired
    • Replies: 0
    • Views: 356
    08-15-2017, 11:37 AM Go to last post
  31. Freidman test with missing values?

    I have a set of data at four time points, but some subjects only two out of the four time points. Can I still use Friedman test for this in SPSS?

    Started by zhu‎, 08-15-2017 11:34 AM
    • Replies: 0
    • Views: 200
    08-15-2017, 11:34 AM Go to last post
  32. Propensity Score Matching

    Hi! I'm conducting a retrospective study in which we want to analyze time period of 60 days before occurence of a particular adverse event. To do...

    Started by joanna513‎, 08-09-2017 07:06 AM
    propensity score matching
    • Replies: 1
    • Views: 447
    08-09-2017, 08:56 AM Go to last post
  33. Poisson Standard Deviation

    Hi! Just a sanity check as I have to do a few computations for a report manually. Our indicator is defined in the following way: #...

    Started by jamesmartinn‎, 06-05-2017 10:03 AM
    • Replies: 6
    • Views: 1,065
    08-08-2017, 09:34 PM Go to last post
  34. Normal Approximation, Fisher's Exact Test, Relative Risk or Odds Ratio?

    A clinical trial is being planned, in which the primary outcome is binary (success/failure). There are two treatment groups (treatment/control). The...

    Started by WeeG‎, 06-17-2017 01:06 PM
    • Replies: 7
    • Views: 967
    08-08-2017, 09:33 PM Go to last post
  35. Help with correct statistical analysis?

    I am conducting an audit into vitamin D deficiency in children. I have the mean serum concentrations of vitamin D in specific areas (postcodes)...

    Started by MedStudent‎, 07-03-2017 05:54 PM
    • Replies: 5
    • Views: 814
    08-08-2017, 09:32 PM Go to last post
  36. Statistical significance

    Hi, I have the following problem and I would need some piece of advice to solve it: I have a group of 28 patients (17 survived, 11 died) and I...

    Started by Carcassonne‎, 07-10-2017 02:51 AM
    • Replies: 8
    • Views: 753
    08-08-2017, 09:31 PM Go to last post
  37. Critiquing a Network Meta-analysis: Interpreting inconsistency

    Hi all. I'm a non-statistician trying to critique a network meta-analysis on a group of migraine medications called triptans (PDF link). The...

    Started by networkMA‎, 07-18-2017 02:18 PM
    • Replies: 3
    • Views: 439
    08-08-2017, 09:30 PM Go to last post
  38. Exclamation STATA Logistic Regression Intepretation

    Hi, My dependent variable is goes to college coded 0=No and 1= Yes. I am not sure how STATA reads/ranks the dependent variable....thus I am not...

    Started by I_AM_KB‎, 08-03-2017 02:53 PM
    interpreting odds ratios, logistic regression, stata
    • Replies: 0
    • Views: 397
    08-03-2017, 02:53 PM Go to last post
  39. Sphericity with unequal sample sizes

    Hello, I want to do a repeated measures anova in R on a data set consisting of four treatments on subjects, over 4 weeks. However, in week 3 I am...

    Started by Wouterka‎, 07-30-2017 11:21 AM
    • Replies: 0
    • Views: 393
    07-30-2017, 11:21 AM Go to last post
  40. Question Need Appropriate Test for comparing a series of measurements from one bone to another

    My research involves taking measurements at 9 sections at different locations on the shaft of bones. I am having trouble determining which...

    Started by SierraS‎, 07-13-2017 11:58 PM
    bone, pair, series, test
    • Replies: 2
    • Views: 585
    07-23-2017, 08:41 PM Go to last post
  41. Online Biostatistics Course/Master's Degree

    Hi everyone, I'll be glad if someone could recommend me some online Biostatistics Course or Master's Degree for beginner. Thanks!

    Started by ovallecc‎, 07-20-2017 03:07 AM
    • Replies: 1
    • Views: 662
    07-20-2017, 04:23 AM Go to last post
  42. Patient-year Incidence rates comparisons and p value

    Dear all, I would like to statistically compare two incidence rates from two different groupes. I found the Incidence rate difference (IRD)...

    Started by didye‎, 07-19-2017 04:43 AM
    compare rates, incidence rate, ird
    • Replies: 0
    • Views: 410
    07-19-2017, 04:43 AM Go to last post
  43. Help with comparing disease death rates over time

    Hello everyone, I am working with a national mortality file and have pulled certain deaths for a particular disease and created crude rates by...

    Started by LAM_13‎, 07-17-2017 07:03 PM
    • Replies: 0
    • Views: 1,245
    07-17-2017, 07:03 PM Go to last post
  44. Software for NHANES Analysis

    Hello! I'm going to be using NHANES data for some of my research looking at dietary factors and health-related outcomes. I have a bit of exposure to...

    Started by mam326‎, 07-14-2017 04:25 PM
    • Replies: 0
    • Views: 478
    07-14-2017, 04:25 PM Go to last post
  45. Multi-level Meta-regression using random effect for treatment? [R pkg metafor]

    I am a biostatistician consulting on a meta-analysis of 16 studies each w/ 2 treatment arms. The main interest is in the effect of the variable...

    Started by chelbylu‎, 07-06-2017 03:45 AM
    hierarchical model, meta-regression, r metafor, random effects, treatment
    • Replies: 0
    • Views: 507
    07-06-2017, 03:45 AM Go to last post
  46. Help choosing right statistics

    The experiment consisted of testing the effect of several diets on the weight of fish. I want to check what groups differ from each other. There is...

    Started by Andre Barreto‎, 06-26-2017 02:58 PM
    • Replies: 2
    • Views: 714
    06-26-2017, 04:06 PM Go to last post
  47. sample size calculation for chi square test with more than 2 groups

    Greetings everybody I'm running a sample size estimation for a study that will use chi square test of association for the qualitative comparison of...

    Started by Bassam‎, 06-07-2017 06:23 PM
    • Replies: 4
    • Views: 1,374
    06-08-2017, 10:58 AM Go to last post
  48. test for cumulative analysis of outcomes over time in meta-analysis

    A systematic review and meta-analysis I am reading references having tested for chronological cumulative analysis for the effects of the outcomes...

    Started by Roundtoit‎, 06-02-2017 05:41 PM
    • Replies: 3
    • Views: 1,282
    06-04-2017, 03:02 PM Go to last post
  49. Simple question re retrospective study types

    Hi, Please could someone confirm that I'm using the correct terminology to describe two studies listed below. I think that they are both...

    Started by ConnemaraPony‎, 05-30-2017 01:31 PM
    • Replies: 2
    • Views: 1,713
    05-30-2017, 03:48 PM Go to last post
  50. Non Inferiority with a Historical Control

    Is it possible or valid to do a Non-Inferioirty Test againts a historical control. I should point out for the historical control all I have is a...

    Started by polc1410‎, 05-30-2017 04:09 AM
    • Replies: 1
    • Views: 983
    05-30-2017, 08:46 AM Go to last post
  51. Should I perform a PCA on my datas?

    Hi, I'm new to the statistic world. I have doubts about pca. I am performing the statistics of my study and I have a lot of data. I wonder if I can...

    Started by Clarissa‎, 05-26-2017 08:36 AM
    • Replies: 0
    • Views: 993
    05-26-2017, 08:36 AM Go to last post
  52. covariate for only clinical group

    HI I have tried to find an answer on the web but was not able, and will appreciate your help! I have a question regarding the use of a covariate in...

    Started by newbeeme‎, 05-21-2017 01:48 AM
    • Replies: 3
    • Views: 1,547
    05-22-2017, 09:28 AM Go to last post
  53. Absolute values or Log-transformed data

    I want to perform a non parametric test (mann-whitney) for my experiments that is briefly quantification of viral load (Real Time Polymerase chain...

    Started by julian_DE‎, 05-15-2017 01:06 AM
    • Replies: 3
    • Views: 1,259
    05-15-2017, 08:55 PM Go to last post
  54. Smile Mixed Model Analysis SPSS

    Hello All, I have a data set which I am trying to find out what is the best way to go about analyzing. I have been asking around and was advised...

    Started by quix09‎, 05-15-2017 08:24 AM
    • Replies: 0
    • Views: 1,044
    05-15-2017, 08:24 AM Go to last post
  55. Is Cochran's Q the right test for repeated measures with binary outcomes?

    Hi, I am trying to analyze a data set. The question we are looking at is whether the rate of a successful outcome and the risk of a...

    Started by Jennifer Kosty‎, 05-12-2017 12:15 PM
    • Replies: 0
    • Views: 935
    05-12-2017, 12:15 PM Go to last post
  56. Different proportions in different conditions?

    Hi, I am struggling with the proper way to analyze my data. I did some research in and out of this forum but could not find the answer to my...

    Started by Fanny-‎, 04-11-2017 08:06 AM
    • Replies: 3
    • Views: 2,012
    05-07-2017, 03:06 AM Go to last post
  57. GLM with non-linear predictor

    Hi, I am analyzing a dataset looking at procedural skill development. The data itself is binomial, whether or not a procedure was successful. When...

    Started by amw2320‎, 05-06-2017 11:02 PM
    • Replies: 0
    • Views: 924
    05-06-2017, 11:02 PM Go to last post
  58. Contingency tables with proportions only

    Hi, I have a 3x2 contingency table, which contains the observed and expected allele frequencies from a hypothetical population and I'd like to test...

    Started by Acather96‎, 05-04-2017 02:23 PM
    • Replies: 8
    • Views: 2,045
    05-04-2017, 05:59 PM Go to last post
  59. Post Chi-square goodness of fit test

    Hi all, I'm currently conducting research at a radiology department. The setup of our research is that we let 2 radiologists indicate their...

    Started by MaxTalksStats‎, 05-01-2017 03:29 AM
    • Replies: 1
    • Views: 1,161
    05-01-2017, 04:23 AM Go to last post
  60. Association/ correlation binary and continuous data non-normal distribution

    Hi, I want to perform an association analysis between a binary (dichotomous?) variable and continuous variable. The binary variable is whether...

    Started by Hannah212‎, 04-27-2017 03:37 AM
    binary, continuous, correlation analysis, point-biserial
    • Replies: 5
    • Views: 1,209
    04-27-2017, 02:59 PM Go to last post

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