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Forum: Biostatistics

Epidemiology and biostatistics, public health research. GLM, logistic regression, survival analysis, clinical trials.

  1. "As treated" analysis, fixed cohort analysis, and NNH?

    I had a few questions in regards to this study: http://www.bmj.com/content/346/bmj.f880.pdf%2Bhtml They conducted an "as treated" analysis and...

    Started by Matt1147‎, 06-23-2013 09:50 PM
    • Replies: 0
    • Views: 2,747
    06-23-2013, 09:50 PM Go to last post
  2. "Is there a sig. difference in amount of subunits between 2 groups according to age"

    Hello! I think I've said it all in the title. I need to run right statistics to answer my question. I guess I have 2 independent variables (age in...

    Started by Tamara‎, 12-03-2013 11:54 AM
    anova, linear, regression, study, variables
    • Replies: 0
    • Views: 1,236
    12-03-2013, 11:54 AM Go to last post
  3. 2 methods proportional hazard in SPSS

    Goodafternoon, (Answers are welcome in English, Dutch and German) I have a question concerning how to test for the proportional hazard assumption,...

    Started by dllique‎, 06-23-2011 09:19 AM
    • Replies: 0
    • Views: 8,418
    06-23-2011, 09:19 AM Go to last post
  4. 2 roc curves (from a study with 2 biomarkers) in one curve

    Hy, I have a problem about solving something in R. It's about 2 roc curves of a 2 biomarkers... and I have to plot it in one curve and calculate the...

    Started by raluca‎, 10-16-2015 08:59 AM
    roc curves
    • Replies: 3
    • Views: 2,521
    10-16-2015, 12:45 PM Go to last post
  5. 2 x 2 ANOVA vs. Paired t-test

    I'm trying to figure out which is more appropriate for a trial. I have two groups in a double-blinded, randomized, placebo-controlled trial. We are...

    Started by ricktan‎, 02-09-2011 12:37 PM
    • Replies: 0
    • Views: 4,491
    02-09-2011, 12:37 PM Go to last post
  6. 2-way Anova design repeated across an extra factor. Which approach is the best?

    Hello to everybody, I am a student working on a trial experiment to find the best combination of growing media, fertilizer application and...

    Started by Augustas‎, 06-28-2014 10:52 AM
    • Replies: 0
    • Views: 1,461
    06-28-2014, 10:52 AM Go to last post
  7. 2-way ANOVA on non-normal, hetergeneous data

    I'm trying to analyze growth data from chicks, and I need to perform the equivalent of a 2-way ANOVA (2x2 design, unequal sample sizes), but my data...

    Started by mogetons‎, 05-23-2011 06:59 PM
    • Replies: 8
    • Views: 29,204
    06-01-2015, 05:19 AM Go to last post
  8. 2-way ANOVA or not 2-way ANOVA?

    Hi, I'm currently doing an experiment assessing the effect that 4 different growth mediums have in 3 different O2 concentrations. There are 6...

    Started by Kudu97‎, 07-08-2014 07:09 AM
    • Replies: 1
    • Views: 1,322
    07-08-2014, 08:51 AM Go to last post
  9. 2-way ANOVA-like analysis with binomial RVs?

    Hi, I have a biological dataset and I'm trying to see if certain treatments are correlated with significant changes. In each sample, I'm...

    Started by nestor‎, 11-20-2010 10:52 PM
    • Replies: 0
    • Views: 6,549
    11-20-2010, 10:52 PM Go to last post
  10. 2-way repeated measures ANOVA with 2 many repeated measures

    Hi, I am looking a several genes and I have measured a value for several exons of these genes (range: 4 to 87). I am looking at the difference...

    Started by mousme‎, 03-23-2012 11:12 AM
    • Replies: 0
    • Views: 1,762
    03-23-2012, 11:12 AM Go to last post
  11. 2^4 On-farm trial - only 4 plots per farm -> what design possibilities?

    Hello, I have to design an on-farm trial with possibly about 600 farmers involved (setting: Madagascar, so rather illiterate participants). ...

    Started by Suzany‎, 08-15-2013 05:19 AM
    multi-factor model, on farm trial
    • Replies: 1
    • Views: 1,397
    08-28-2013, 03:17 AM Go to last post
  12. 3 study areas - changes in incidence/prev over time within AND between study areas?

    Hi everyone, I just thought it's easiest if I go through my research plan and the aim to put things into context. I've been told one thing by one...

    Started by wernie‎, 06-01-2012 11:44 PM
    prevalence incidence
    • Replies: 0
    • Views: 2,215
    06-01-2012, 11:44 PM Go to last post
  13. 3-group analysis

    Hello, I have little project, and today doubts just brought me down. I have sample of 25 patients, and 3 types of disease (a person can have more...

    Started by yooguruto‎, 07-26-2010 01:25 PM
    • Replies: 0
    • Views: 3,598
    07-26-2010, 01:25 PM Go to last post
  14. 3D printing project + small sample size (5). How to analyze questionnaire data?

    Hi there, I am currently working on a research project investigating the use of 3D printed patient specific anatomy in pre-operative planning. The...

    Started by stanleyliew‎, 07-24-2014 04:54 PM
    • Replies: 0
    • Views: 1,405
    07-24-2014, 04:54 PM Go to last post
  15. Question 4 proportions to compare, each with separate N and 95% CI. use ANOVA or what?

    With the above info, what's the correct way to determine whether the proportions differ significantly? I thought I had a lovely formula that used...

    Started by StatsIsPain‎, 10-23-2014 07:52 PM
    • Replies: 1
    • Views: 1,255
    10-23-2014, 09:42 PM Go to last post
  16. ?Pearson ?point-biserial correlatiom coefficient for relationship between variables

    Hi, I'm new on this forum, thanks for reading my post! I'm trying to figure out if I've used the best method for determining a relationship between...

    Started by waynes‎, 10-27-2014 06:08 PM
    biostatistics, pearson correlation, point-biserial, valid
    • Replies: 0
    • Views: 1,264
    10-27-2014, 06:08 PM Go to last post
  17. A better way to pick up on hidden variables

    Hi, I'm trying to determine cattle disease risk through various values, including weight, through a machine learning application. I have the usual...

    Started by shred14‎, 06-10-2013 01:05 AM
    • Replies: 1
    • Views: 1,488
    06-12-2013, 12:30 AM Go to last post
  18. A cohort clinical trial?! Does it really exist?

    I saw a study which meets the criteria for a cohort study (without a control though) but it reads a cohort clinical trial! Can you tell me is it...

    Started by victorxstc‎, 09-18-2011 08:47 AM
    • Replies: 1
    • Views: 1,796
    09-19-2011, 07:48 PM Go to last post
  19. A couple of questions about results in computational neuroscience

    Hi guys, This is my first time posting here. I am a medical student and I have been conducting research in computational neuroscience over the...

    Started by ilzwalrus‎, 07-09-2015 12:32 PM
    • Replies: 0
    • Views: 1,185
    07-09-2015, 12:32 PM Go to last post
  20. A different way of presenting this data

    Hi folks, I wonder if you could help me? I'm filling in for someone at work and I'm want to express this data in a simple lay person way,...

    Started by dukduk‎, 12-04-2012 04:40 AM
    • Replies: 0
    • Views: 1,555
    12-04-2012, 04:40 AM Go to last post
  21. A doubt in the terminology of sample size calculation

    Hi all, While going through a published article of a clinical trial in cervical cancer, I came across this statement under statistical...

    Started by placebo‎, 03-11-2009 03:59 AM
    • Replies: 0
    • Views: 2,275
    03-11-2009, 03:59 AM Go to last post
  22. Unhappy A dumb question about univariate analysis (repost from applied statistics)

    Hello I'm quite dumb regarding statistics, but i really am looking for a simple answer to a simple question. the question is: how do i explore data...

    Started by Kimboz‎, 12-19-2014 04:05 AM
    • Replies: 2
    • Views: 1,683
    12-19-2014, 05:54 AM Go to last post
  23. A Question regarding the Kaplan Meier survival curve.

    Hello guys I have a set of epidemiological data for a group of patients whom were followed up for a specific time period. The mortality rate was...

    Started by scerab‎, 01-20-2011 02:14 AM
    • Replies: 5
    • Views: 13,372
    02-25-2013, 02:11 AM Go to last post
  24. a series of T tests more appropriate than ANOVA here?

    Hi all, I'm writing up some experimental results, which I believe I know how to analyze, but wanted to get some frank and impartial feedback before...

    Started by BWGIA‎, 07-03-2011 09:18 PM
    anova, dunnett t test, t test
    • Replies: 10
    • Views: 6,731
    09-19-2015, 05:02 AM Go to last post
  25. a simple question

    Hi, As you can tell I am statistically challenged. Suppose x and y are continuous, independent variables that represent traits of the N subjects...

    Started by danb‎, 08-28-2011 09:02 PM
    biostatistics
    • Replies: 2
    • Views: 2,133
    08-29-2011, 01:46 PM Go to last post
  26. A T test question

    This is a question on presenting the result of the effectiveness of weight loss program. There is only one group of subject and two time point ( pre...

    Started by kolokicy‎, 04-22-2013 09:45 PM
    • Replies: 4
    • Views: 1,862
    04-23-2013, 04:45 PM Go to last post
  27. A tough question: How can I compare 2 sets of coordinates?

    Dear All Please help! I have a set of data for children examined for an eye condition (n=334) All children were examined at 35 weeks of age...

    Started by SiBorg‎, 11-19-2011 05:03 AM
    • Replies: 4
    • Views: 3,808
    11-19-2011, 06:21 AM Go to last post
  28. About Confidence Interval

    I have done frequency analysis using spss and now person is asking CI How to find CI

    Started by tpachhai‎, 09-09-2011 07:35 AM
    • Replies: 1
    • Views: 1,957
    09-15-2011, 03:23 AM Go to last post
  29. Absolute values or Log-transformed data

    I want to perform a non parametric test (mann-whitney) for my experiments that is briefly quantification of viral load (Real Time Polymerase chain...

    Started by julian_DE‎, 05-15-2017 01:06 AM
    • Replies: 3
    • Views: 1,281
    05-15-2017, 08:55 PM Go to last post
  30. accelerated time model with proportional hazards

    $coef Estimate SE lambda 0.004424690 0.005026449 gamma 0.888627728 0.108972639 treatment -0.646997631...

    Started by studentbelg‎, 05-29-2014 08:02 AM
    • Replies: 1
    • Views: 1,362
    05-29-2014, 07:11 PM Go to last post
  31. Accounting for demographics when outcome is rates

    Hello, I've been reading some public health papers and they account for demographic factors such as age, gender, and race in regression models...

    Started by phbios321‎, 06-13-2013 11:33 AM
    adjustment, crude rates, demographics, poisson regression
    • Replies: 7
    • Views: 2,178
    06-19-2013, 03:15 PM Go to last post
  32. accounting for left-truncation is STATA

    Hi, I have yet another question about survival analysis, this time regarding the appropriate code using STATA. I am trying to account for...

    Started by Basia.‎, 10-09-2015 08:49 AM
    • Replies: 0
    • Views: 1,587
    10-09-2015, 08:49 AM Go to last post
  33. Accounting for random effects from sampled individuals in GLM

    Hello, this is my first post but I am sure it won't be my last. I am working on my thesis and just sent the first round of analyses to my committee....

    Started by zombie_kid‎, 02-04-2014 09:32 PM
    • Replies: 11
    • Views: 2,253
    02-06-2014, 01:37 PM Go to last post
  34. Accounting for spatial autocorrelation in neural network analysis in R

    Hi all, I have been exploring the use of neural networks to identify relationships between large numbers of differing species and the presence of...

    Started by AaronMo‎, 02-01-2014 06:07 AM
    neural networks, spatial autocorrelation
    • Replies: 0
    • Views: 1,103
    02-01-2014, 06:07 AM Go to last post
  35. Add AUCs

    I want to add Area Under the Curve (AUC) from multiple meta analyses. AUC for each Meta analysis is given. How can I add them together?

    Started by Michael_svm‎, 12-20-2016 05:24 AM
    area under the curve, auc, diagnostic, roc
    • Replies: 6
    • Views: 4,249
    12-23-2016, 08:08 AM Go to last post
  36. Adjusted Chi-squared test for clustered binary / categorical data

    I'm looking for some assistance in statistical analysis with R (ideally), but also some general stats advice. This follows from a review which...

    Started by ugm6hr‎, 02-17-2013 10:08 AM
    chi-squared, clustering, proportions
    • Replies: 0
    • Views: 3,464
    02-17-2013, 10:08 AM Go to last post
  37. Adjusted Odds Ratio

    Hi to everybody, does anybody knows how to calculate Adjusted Odds Ratio when I have a Multiple Logistic Regression model? Do you know about...

    Started by Canyon75‎, 12-30-2008 05:34 AM
    • Replies: 1
    • Views: 7,748
    12-30-2008, 05:09 PM Go to last post
  38. Adjusted Risk Ratios (proc genmod)

    I'm looking at some risk factors associated with infant death comparing different races to a reference group. I calculated crude risk ratios...

    Started by RyanD‎, 06-20-2011 10:54 AM
    • Replies: 2
    • Views: 8,519
    06-20-2011, 11:39 AM Go to last post
  39. Adjusting for clustered observations

    Hello, I have collected mortality data and several covariates (data on treatment and vital parameters) from patients in two different hospitals....

    Started by Patrick‎, 02-22-2016 03:52 AM
    fixed effect, gee, logistic regression, random effect
    • Replies: 5
    • Views: 2,489
    02-25-2016, 12:17 PM Go to last post
  40. Adjusting for repeat-test-exposure bias in diagnostic accuracy studies

    I'm conducting a metaanalysis pertaining to diagnostic accuracy of an index test compared to the reference standard, and for my question on this...

    Started by Borazja‎, 07-04-2013 03:50 PM
    diagnostic accuracy
    • Replies: 0
    • Views: 1,690
    07-04-2013, 03:50 PM Go to last post
  41. ADjusting for variables in regression model

    Dear all, I'm comparing two populations of oncologic patients that were treated with two different regimens in two different hospitals, group A of...

    Started by Markica85‎, 02-13-2017 06:43 AM
    • Replies: 6
    • Views: 2,462
    02-22-2017, 01:56 PM Go to last post
  42. Adjustment for confounders for testing equality of variance

    Dear all I wonder if there is a method that allows to adjust for confounding variables when testing for the equality of variances. I am comparing...

    Started by sternchen‎, 05-14-2015 05:06 AM
    • Replies: 1
    • Views: 1,164
    05-14-2015, 05:33 AM Go to last post
  43. Adjustment for correlated data in meta-anlaysis

    Hi, I'm completing a systematic review and performing meta-anlaysis forest plots. The research question related to the finding of risk factors for...

    Started by Ainslie‎, 03-08-2017 12:47 AM
    adjustment, correlated data, meta-analysis
    • Replies: 2
    • Views: 1,905
    03-08-2017, 11:07 AM Go to last post
  44. Adjustment for Odds Ratios

    At present, I am working on a meta-analysis that observes the effect of physical activity for a disease (i.e. cancer). For each study we have used...

    Started by jle‎, 05-13-2015 06:24 PM
    • Replies: 10
    • Views: 2,034
    05-17-2015, 09:31 PM Go to last post
  45. Adverse drug reaction; multiple drugs, possible event(s) per patient. What analysis?

    Hello everyone, I am currently looking for the right method to compare the incidences of a given adverse drug reaction (infection) after the...

    Started by maksler‎, 01-24-2012 04:25 AM
    adverse drug reaction, design, observational study
    • Replies: 0
    • Views: 2,316
    01-24-2012, 04:25 AM Go to last post
  46. Advice on appropriate test on proportions with three factors with replication

    I am planning a study with three factors (salinity, parasite type and species). Can anyone suggest an appropriate statistical test? I am wondering if...

    Started by luhar‎, 05-01-2015 02:00 PM
    • Replies: 0
    • Views: 1,580
    05-01-2015, 02:00 PM Go to last post
  47. Advice on linear mixed model on longitudinal data

    Hello, I have a longitudinal dataset of cumulative biomass from an experiment. The subjects have been exposed of 3 different treatments (LOW, MED,...

    Started by and0s‎, 07-28-2013 05:20 AM
    • Replies: 2
    • Views: 2,027
    07-28-2013, 10:14 AM Go to last post
  48. Thumbs down Advise on choosing statistical method

    Hi. I'm a medicine student and I'm relatively new to statistics. I'm looking at some data and I can not figure out which statistical method I should...

    Started by orangemasa‎, 11-02-2013 04:01 AM
    • Replies: 4
    • Views: 2,070
    11-19-2013, 10:26 AM Go to last post
  49. Age-adjusted Cumulative incidence

    Hello, Somebody knows what is the method to calculate an age-adjusted cumulative incidence for a clinical event? Also, could you tell me if...

    Started by didye‎, 11-06-2014 01:34 PM
    • Replies: 1
    • Views: 1,444
    11-06-2014, 04:32 PM Go to last post
  50. Age-adjusting survey data to compare weighted estimates from multiple surveys?

    Hello, I am looking to compare weighted estimates (counts and proportions) of people with disabilities from the National Health Interview Survey,...

    Started by GrumpyEpiGuy‎, 09-03-2015 01:36 PM
    • Replies: 0
    • Views: 1,790
    09-03-2015, 01:36 PM Go to last post
  51. Aggregate trend analysis

    Someone I work with said they ran across a paper on a study that contained an analysis which looked at the results of several different outcomes to...

    Started by mostater‎, 10-13-2010 03:35 PM
    • Replies: 0
    • Views: 5,271
    10-13-2010, 03:35 PM Go to last post
  52. Agreement between raters who record the frequency at which they would choose options

    Say I have 5 raters and 6 choices. For each choice, each rater records a frequency from 0 to 100: the percentage of time they would choose that...

    Started by emogene‎, 12-17-2015 10:01 AM
    agreement
    • Replies: 0
    • Views: 907
    12-17-2015, 10:01 AM Go to last post
  53. Aic & bic

    Hello I have a little question. I have learned that we use AIC and BIC to compare models and to choose the best model to fit our data. I learned...

    Started by WeeG‎, 12-29-2012 04:15 PM
    • Replies: 2
    • Views: 2,797
    12-30-2012, 01:30 AM Go to last post
  54. AIC for multivariate linear regression

    I am hoping to use AIC to evaluate multivariate linear regression models including interaction terms. Is this possible? If so, how does one determine...

    Started by kpete‎, 02-16-2013 01:22 PM
    • Replies: 2
    • Views: 4,431
    02-18-2013, 08:31 PM Go to last post
  55. Allowing for time-dependent covariates in power calculations

    Hi all, I'm familiar with how to undertake a power calculation to estimate sample size in an unmatched case-control study. Sample size will be...

    Started by dhj_davis‎, 12-12-2011 01:12 PM
    • Replies: 0
    • Views: 1,796
    12-12-2011, 01:12 PM Go to last post
  56. alpha in one sided tests

    hello all, i have a theoretical question, i have found out that on medical research, when performing a one sided test (instead of the preferable...

    Started by WeeG‎, 10-26-2013 02:59 AM
    • Replies: 5
    • Views: 9,626
    10-27-2013, 08:22 AM Go to last post
  57. Alternative to McNemar's Test

    Hello all, I want to run the McNemar's Test for matched binary data, however my sample is small (n=10 pairs), and the normal approximation cannot...

    Started by NN_STAT‎, 07-15-2013 08:01 AM
    • Replies: 1
    • Views: 5,073
    07-24-2013, 12:32 PM Go to last post
  58. Am I allowed to pool groups for GLM?

    Here is my problem: I am doing a stability study, for which I have several lots on different storage temperatures. In order to asses the...

    Started by gamadeus‎, 07-13-2012 12:43 PM
    • Replies: 3
    • Views: 1,895
    08-03-2012, 09:15 AM Go to last post
  59. Am I introducing a selection bias in my prognostic biomarker study ?

    Hi all, I'd be glad to get the advice from someone who's better than me at biostatistics, especially regarding selection biases in survival...

    Started by Debby 02‎, 02-23-2016 05:14 PM
    • Replies: 5
    • Views: 1,049
    02-24-2016, 09:12 AM Go to last post
  60. am i overadjusting?

    might sound silly but for my research topic I am looking into insulin resistance (IR) and dietary factors. We are measuring IR by the use of...

    Started by jkerr1‎, 03-27-2017 04:56 AM
    • Replies: 1
    • Views: 1,134
    03-27-2017, 10:23 AM Go to last post

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