+ Reply to Thread
Results 1 to 4 of 4

Thread: ROC curves - an appropriate use?

Hybrid View

  1. #1
    Points: 638, Level: 12
    Level completed: 76%, Points required for next Level: 12

    Posts
    3
    Thanks
    1
    Thanked 0 Times in 0 Posts

    Post ROC curves - an appropriate use?

    Hi all,

    I am new to ROC curves. My only experience is using them to examine tests for a specific disease, however I wonder if my plans below are an acceptable use for ROC curves..

    My data is as such:

    Days on dialysis (kidney replacement) (days; and categorised into zero, <1 week of dialysis, >1 week dialysis)
    Survival greater than 1 year (yes/no)

    I'd be very grateful if someone can advise whether my scenario is compatible with a ROC curve.

    Many thanks, David

  2. #2
    Points: 1,259, Level: 19
    Level completed: 59%, Points required for next Level: 41

    Location
    Denver, CO, USA
    Posts
    59
    Thanks
    7
    Thanked 11 Times in 10 Posts

    Re: ROC curves - an appropriate use?

    Yes, you can use a ROC curve for this, though you'll need to do some work. You can't really do it with the discretized version of days -- or rather, you could, but it would be boring. But the raw days measurement is close enough to continuous to make sense for ROC analysis. At a guess, S=1 (survival > 1 year) is negatively correlated with D (days on dialysis), correct? So for some given number of days d, you'd treat D \leq d as a "positive days result" and D > d as a "negative days result," and similarly S=1 as a "positive survival result" and S=0 as a "negative survival result." Here S=1 is the "gold standard", so, for example, S=1, \ D > d is a false negative. Plot the results for d = 1, \ldots, d_{max} where d_{max} is the greatest number of days anyone spends on dialysis, and you have your ROC curve.

    (Note: I may have the signs wrong, in which case the \leq and > signs up above should be reversed. But that's the general idea.)

  3. The Following User Says Thank You to Daniel Dvorkin For This Useful Post:

    dhmallon (04-08-2012)

  4. #3
    Points: 638, Level: 12
    Level completed: 76%, Points required for next Level: 12

    Posts
    3
    Thanks
    1
    Thanked 0 Times in 0 Posts

    Re: ROC curves - an appropriate use?

    that makes perfect sense - thank you very much indeed!

  5. #4
    Points: 1,259, Level: 19
    Level completed: 59%, Points required for next Level: 41

    Location
    Denver, CO, USA
    Posts
    59
    Thanks
    7
    Thanked 11 Times in 10 Posts

    Re: ROC curves - an appropriate use?

    You're welcome!

    One thing that occurred to me after I wrote this is that there's no reason to assume that Pr(S=1|d=d_{max}) = 0 or Pr(S=1|D=1) = 1, so the curve you get out of this might not necessarily run from (0,0) to (1,1) like a traditional ROC curve, for a test where (\text{sensitivity}) = 0 \Rightarrow (\text{specificity} = 1), does. However, the curve will still be within the unit rectangle, and the area under the curve should still be a valid measure of the power of D to predict S.

+ Reply to Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts








Advertise on Talk Stats