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Thread: Help in interpretation of mixed model output

  1. #1
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    Help in interpretation of mixed model output



    Hello,

    I ran a model in Stata after finding a syntax online, I wanted to ask if I ran the correct model and to ask for help in interpretation.

    The study endpoint is an eye disease in animals. The animals are randomly grouped into 3 different groups (a new tested treatment vs. positive and negative controls).
    For each animal, the status of the disease is tested in both eyes, making the study a repeated measures study. The response (status of disease) is ordinal.

    I wanted a model that will compare the treatments vs. the response, while taking into account the obvious correlation between two eyes from the same animal (correlation exists, I checked it).

    I ran this syntax I found:

    Code: 
    xtreg  Score i.Group##i.Eye, i( Animal) mle nolog
    and got the output in the attached photo.

    I wanted to ask:

    1. Is my model correct for a start ?
    2. How do I interpret the results ? Group 1 is the new treatment, group 2 is the negative control and group 3 is the positive control.
    3. My response is not really Gaussian, how badly does it effect the results ?
    4. Would I get different results using xtmixed ?

    An answer to ANY of these questions will be most helpful ! Thank you very much !
    Attached Images  

  2. #2
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    Re: Help in interpretation of mixed model output

    In addition to my post, I ran the model again without interaction and got the attached output. The models differ significantly (p values of groups 1 vs 2).

    The AIC and BIC of the first model are 206.7218 and 224.9352 respectively. The ones of the second model are attached.

    Perhaps the extra information will help ?
    Attached Images  

  3. #3
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    Re: Help in interpretation of mixed model output


    I also ran an ordered logistic, and the output is also attached, the code was:

    Code: 
    ologit Score i.Group##i.Eye, cluster(Animal) nolog
    I apologize for the 3 parts thread, I thought any additional information would help...
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