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Thread: ANOVA or Kruskal Walli

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    ANOVA or Kruskal Walli




    Hi!

    I have measured respiration in 3 treated and one untreated control cell line with N= 27, 25, 31 & 31. Can I use a one way anova or should I use a kruskal wallis test? Or are there any better options?

    Thanks
    J

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    Re: ANOVA or Kruskal Walli

    First you should state your hypothesis of interest; what specifically would like to conclude?

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    Re: ANOVA or Kruskal Walli

    I want to see wether there are any significant differences in respiration between the the cell lines.

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    Re: ANOVA or Kruskal Walli

    Hi!
    May be this article will provides some hints for you to decide which test should be used.

    Gm
    http://cainarchaeology.weebly.com/

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    Re: ANOVA or Kruskal Walli


    If you have 1 value for each sample (culture) then one of the two methods you mentioned would be applicable, if not you should look for other ways (I suggest repeated measures one way ANOVA).

    Assuming only 1 value for each sample:
    Kruskal-Wallis tends to have less power than an ANOVA if the population follows assumptions of normality and are homogenous (power is around 95% of that of ANOVA). If however your populations might be somewhat skewed and/or non-normal then Kruskal-Wallis have the same or better power compared to ANOVA.

    In the case of cell cultures I'd say you can assume normality and therefore go with a regular ANOVA.
    If you get a significant result on the ANOVA you can then use a Tukey test with unequal sample sizes to find out which group(s) differ from the rest.

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