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Thread: Which test to use? Fisher exact?

  1. #1
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    Which test to use? Fisher exact?

    Hi all,

    We're studying expression of a protein from benign to primary malignant and metastatic lesions. Let's say 0/15 of the benign, 19/27 (70%) malignant, and 11/19 (60%) metastatic lesions were + for this protein. Fisher's exact says that they are significantly correlated, which is clear from benign to malignant, but what test would I use to determine if the decrease from primary malignant to metastatic is significant?

    Thanks so much for your help!


  2. #2
    Points: 501, Level: 10
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    Re: Which test to use? Fisher exact?

    Paiwaise fisher exact tests.

    benign vs malignant
    malignant vs metastatic

    benign vs metastatic is not relevant I think

    Please note you are doing multiple tests now on the same data (at least 3). You need to lower your alpha accodingly (p<0.05/3)


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