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Thread: Analysis of single arm study

  1. #1
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    Analysis of single arm study

    Hello all,

    I need some help choosing how to analyze my data.

    I have a single arm study, i.e., a study testing a new treatment, but not against a control, so I have one group.

    I have two outcome variables, one is supposed to be continuous with values between 1-10, however in practice all values except two are either 0,1,2. The second variable is binary: success or failure.

    In addition, I have repeated measures, every patient gave 1 or 2 samples.

    What I want to do is to analyze the two variables for this group. Then, I want to analyze again, this time by some factor, for example male vs. female.

    My main questions are:

    1. How do yoy suggest to analyze?
    2. How to I analyze one group with repeated measures? I cant just do estimates with CI and ignore the correlations.
    3. How do I an analyze a binary outcome with repeated measures ?

    my correlation within subject is around 0.85.

    Thank you!

  2. #2
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    Re: Analysis of single arm study

    I think you might be able to do a mixed effects logistic regression.

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