Apologies if this is quite a basic question but I'm fairly new to stats.

I have a 24 x 70 matrix consisting of rows of 24 human serum samples and columns of protein intensity values for 70 different proteins.

The 1st 12 rows are healthy people (type 1), the remaining 12 rows are patients (type 2).

I applied the T test and found 5 proteins which appear to differentiate between healthy people and patients according to p value.

I now want to check whether these proteins are still significant after permutation testing. However I don't know how to do this. I've searched online but this example is more complicated because it's a matrix. Can anyone help?