+ Reply to Thread
Results 1 to 2 of 2

Thread: When to use validation and derivation cohort?

  1. #1
    Points: 11, Level: 1
    Level completed: 21%, Points required for next Level: 39

    Posts
    2
    Thanks
    0
    Thanked 0 Times in 0 Posts

    When to use validation and derivation cohort?




    Hi everyone,

    I was wondering if there is any generic rules on when it's good to use a derivation and validation cohort on a dataset? So far I have only seen them being used for diagnostic tests.

    Also, if I use two datasets from two different studies to do this, do the datasets need to have the same primary endpoint? E.g. I am planning to do the derivation using one dataset and validation using another. The primary endpoint I am looking at is 30 days mortality for my research. One dataset records 30 days mortality, the other one only records in-hospital death within 30 days (if patients die after they are discharged, it is NOT recorded). Would it be correct to use one as validation and other as derivation cohort for this?


    Many thanks.

  2. #2
    Omega Contributor
    Points: 38,396, Level: 100
    Level completed: 0%, Points required for next Level: 0
    hlsmith's Avatar
    Location
    Not Ames, IA
    Posts
    7,001
    Thanks
    398
    Thanked 1,186 Times in 1,147 Posts

    Re: When to use validation and derivation cohort?


    You typically always want apples to apples. I am sure you could list out all of the limitations of comparing two groups with different follow-up (e.g., do patients have the approximate same length of stay, if not why).

    Might be able to compare if most everybody dies with in a day or two while in hospital, that way you would not be missing all of this deaths after discharge.
    Stop cowardice, ban guns!

+ Reply to Thread

           




Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts






Advertise on Talk Stats