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Thread: A nice easy one about Repeated Measures ANOVA

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    A nice easy one about Repeated Measures ANOVA




    Hello!

    A basic question from a not-very-statistically-savvy person:

    I have data from 2 groups of patients who underwent knee replacement operations. One group was pre-conditioned (treatment) the other was not (control).

    Blood samples were taken from both groups at 6 time-points (1 pre-op, 2 intra-op and 3 post-op).

    From those samples the levels of various cytokines with funny names like IL-12p70 and IFN-y were measured.

    I am considering each variable (cytokine) separately and thinking that a repeated measures ANOVA would be the appropriate test to do in order to compare the two groups, but I'm not sure...

    Any thoughts would be much appreciated!

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    Hi okennedy,

    Are the cytokine levels the dependent variables?
    And is treatment the only independent variable (other than time)?

    If so, yes, you want repeated measures anova. In fact, it's a mixed model because time is within subjects (repeated) and treatment is between subjects.

    Karen
    The Analysis Factor
    http://TheAnalysisFactor.com

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    Hi Karen,

    Yes, the cytokines are the dependant variables, and the treatment is the only independant variable other than time.

    So, I'll give the mixed model repeated measures anova a go!

    Thanks a million for your help, it is much appreciated.

    Also, I've just signed up for Statwise - it is a great resource...I'm looking forward to the first newsletter!

    Thanks again,

    Oran

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    Hi Oran,

    Thanks for signing up! Hope you find it useful. The next one goes out next week.

    Karen
    The Analysis Factor
    http://TheAnalysisFactor.com

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    Hi Karen,

    Thanks, I'll look forward to that.

    A quick follow-up question...if I may?

    Resources over here are limited so I tried doing my analysis (two-factor ANOVA with repeated measures on one factor) using an online calculator...and I'm not sure if I'm using it correctly.

    I have entered my data in a 2 row x 4 column structure. Where data in row 1 is control and row 2 is treatment. Each column is a different timepoint.

    The result sheet has various values (SS, df, MS) among them are three F-values of 0.09 for A(between subjects) 2.68 for B(repeated measures variable) and 1.13 for AxB

    So I think I'm either using this tool incorrectly or this experiment shows nothing of interest!

    Here's hoping for the former...

    Thanks again!

    Oran

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    Hi Oran,

    I really can't tell you if you're doing it correctly. There are so many ways to set up the data--it differs for each program.

    Usually each row in a data spreadsheet is a subject and each column is a variable, but even this can vary.

    Karen
    The Analysis Factor
    http://TheAnalysisFactor.com

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