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Thread: Basic help with stats for drug treatments

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    Basic help with stats for drug treatments




    Hi there
    So I haven't a clue where to start and am hoping someone on here can point me in the right direction.
    I'm starting to analyse my data from laboratory research but I don't know which test to use. My data is numerical and follows a normal distribution.

    I have 2 different cell lines - a control and a mutant cell line.
    For each cell line, I have a minimum of 3 and a maximum of 13 different treatments.
    I have 3 replicates for each condition which I can mean average.

    I want to compare treatments to see which is most significant. I also want to see a difference between the cell lines i.e. my drugs should affect the mutant cells and not the control cells.

    I am thinking I should do separate analyses for both cell lines, so to compare drug treatments maybe one-way ANOVA? Then use t-test to directly compare each treatment means between cell lines? This seems kind of long-winded. Help!

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    Re: Basic help with stats for drug treatments


    hi,
    this feels like a two-way Anova, one factor being the group type, the other the treatment. You should look for interaction effects mainly, treatments that have a different effect on the control and the treatment group.
    regards

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