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Thread: How should I connect alleles?

  1. #1
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    How should I connect alleles?




    I am new at statistics and I have problem that I have no idea how to solve.

    I have biological data, which includes expression levels (130 patients) for different alleles (I'm analysing SNP's) of different genes (over 500 000 genes). First thing I did was finding those genes, for whom I have at least 3 patients with each allel (AA, AB, BB). The thing is that I have to analyse those which have less than 3 patients. I have to connect this groups somehow, but I'm not sure how. The only thing I figured out is that I can't connect AA and BB, which from biological point of view is pretty obvious. Only possibilities are to create groups AA+AB or BB+AB, but I have no idea how to choose proper group.

    Is there some statistical rule that would allow me to fit one (or two) value into group?

    Any help will be appreciated

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    Re: How should I connect alleles?

    The only equation i know in this field is:

    genetics+statistics=brain melt.

    There's some smarties on this forum though, so good luck.

  3. #3
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    Re: How should I connect alleles?


    use BCAAs?
    Stop cowardice, ban guns!

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