So, i'm in the process of setting up a trial comparing two different methods of observation and I need to calculate the sample size.
I plan on making it a non-inferiority study in which I hope to prove that the new observational method is equal to or better than the old.
The results will be in terms of proportions to be compared, with the old method in the range of 0.85-0.9 and the margin of equivalence 0.1-0.15 percentage points. I would like a statistical power of 0.8-0.9 and a significance level of 0.05.
Can I calculate my sample size based on this information?