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Thread: Medical stats - which statistical test to use? Stuck!

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    Medical stats - which statistical test to use? Stuck!




    Dear all,

    I need some help with determining what statistical test to use for the following data.

    I have a column for age of patient and I want to compare this statistically with another column where it is stated YES if a infection occured or NO if no infection occured. I have grouped the ages into under 25, 26-35, 36-45......etc and I want to see if there is a statisically significant variation beween the different age groups and the frequency of infections (yes/no) in each age group.

    For example

    under 25: 23 no infection, 3 yes infection
    26-35: 18 no infection, 2 yes infection
    36-45: 22 no infection, 0 yes infection
    46-55: 28 no infection, 4 yes infection
    56-65: 3 no infection, 15 yes infection
    66-75: 23 no infectin, 2 yes infection

    Similarly, I have a column of surgical procedures and I want to also compare this statisically with a column for infection (yes/no) to see if there is a statistical variation between the 30 surgical procedures and the number of infections.

    Also , I have a column of 23 countries of residence and I would like to compare this statically with the number of infections.

    Could someone kindly assist me with this? Which stats test should I use?

    Many thanks!

  2. #2
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    Re: Medical stats - which statistical test to use? Stuck!

    For the age/infection as you have them organized - into age groups - chi-square goodness of fit would work, with age groups as the categories and "proportion having an infection" as the proportions.

    Or if you used age/infection and did not group the ages, you could do logistic regression with age as the predictor and infection (yes/no) as the DV.

    You didn't give a lot of detail about the surgical procedures and countries of residence variables, but they both sound like nominal variables in which case chi-quare GOF test works for those analyses as well.

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    Re: Medical stats - which statistical test to use? Stuck!

    Dear bruin,

    Thank you for your reply.

    With regards to Chi square goodness of fit, would it still be appropriate if more than 20% of variables had a frequency of less than 5?

    With regards to procedure and country of origin the data is like.

    Procedures

    Upper GI surgery: 123 no infection 5 yes infection
    Lower GI surgery: 130 no infection 3 yes infection
    Urology surgery: 46 no infection 1 yes infection
    Orthopaedic surgery: 8 no infection 0 yes infection

    Countries
    Argentina 1 no infection 0 yes infection
    Burma 2 no infection 0 yes infection
    Cyprus 6 no infection 1 yes infection
    UK 128 no infection 6 yes infection
    America 60 no infection 3 yes infection

    There are several frequencies that may be 0 or small numbers.

    Would a Chi squared GOF test be okay?

    Thank you!

  4. #4
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    Re: Medical stats - which statistical test to use? Stuck!


    That's a good question; no, it may not be appropriate to do a Chi-Square GOF when the expected frequencies are very low.

    Check these out, they may help:

    http://www.theanalysisfactor.com/obs...est-no-biggie/

    http://www.biostathandbook.com/small.html

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