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Thread: Sensitivity analysis - meta-analysis

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    Sensitivity analysis - meta-analysis




    When doing a meta-analysis with few studies (n < 6), would it be acceptable that sensitivity analysis shows that removal of each study would change the effect size from significant to non significant (or vice-versa)? (low number of studies = more determinant impact of each study?)

    Thank you very much!

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    Re: Sensitivity analysis - meta-analysis


    I would imagine that in a MA w/ </= 6 studies you would still do sensitivity analysis. Whether the removal of one study has an impact would be based on your study context and partial study contribution to the overall estimate.


    One would also imagine that the fewer studies you have the greater the impact of removing one study, given that there is not homogeneity in all of the study results. I would also wonder if the SE may also increase since you have fewer observations (so regardless of the individual study results). Maybe more attention is given to the estimate than to its actual significance.
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