gene expression

  1. A

    Statistical method for evaluating gene expression

    Hey guys, I am trying to see how one gene affect other gene expression in cancer. I am going to be using microarray data to obtain mrna, mutation and copy number data and then I will analyse it against other genes mrna data to see if they are downregulated or upregulated in presence of the...
  2. R

    How to check if vector is close to space spanned by 2 basis vectors (lin. regression)

    Here is the situation: I have measured gene expression data for cells that have been subjected to three different stimuli. This means I have 3 long vectors with numbers that describe how active each gene is in each sample. To clarify: say we are looking at sample one, I have a number for each...
  3. O

    likelihood of false positive in Robust regression model. Gene expression results

    :shakehead Hi I'd like to calculate the probability of a gene A or genes A , B, C and D occuring due to chance alone in a genelist of concordant genes derived from two separate methods using the same conditions. 1. Significance of microarrays analysis of Disease v Control yielded 500 results...
  4. J

    Gene expression analysis - FDR and p-values

    Hi, I'm using Affymetrix microarrays to check if there exist some differences in the gene expression of two group of animals that have been differently treated. I'm using a t-test with permutations (as my groups only have three animals and I read that it is better to use permutation if you...