meta analysis

  1. R

    Looking for the appropriate stat test

    I am attempting to do a meta-analysis to understand a treatment effect . There are groups across many studies which have treatments A and B and a control group without any treatment. In other studies, there are groups with just treatment A and control groups. I am trying to understand what the...
  2. P

    Graph trend line from meta-analysis (multiple pooled studies)

    Hi! I have searched the web and have found no convincing answer, although this should be pretty easy. My question separates into 2: 1- Is it reasonable to trace a trend line of the evolution of a parameter over time from the pooling of different studies, each of which do not contain all time...
  3. K

    Creating Z-Scores for Meta-Analysis

    I will be conducting a meta-analysis that compares post-treatment changes in depression between the control and intervention groups. I have the Mean, SD, and N for depression at both time-points. Since different studies used measures to assess depression, I was planning to convert the change...
  4. S

    Likelihood ratio or wald test for meta-analysis

    Hi there! This is my first time posting but I've always been a frequent lurker on previous posts that have been super helpful, so apologies if I'm not following any appropriate etiquette. I am working on an RNA sequencing project and looking have different outputs, which provides either a...
  5. I

    Regression analysis across multiple data sets

    Hi All. I'm new to this forum but I have a background in stats and in business/social science research. I'm in the early stages of designing a research study that will analyze a large dataset for about 100 publicly traded companies. There will be about 10-20 independent variables for each...
  6. L

    calculating standard error and variance of correlation estimates

    Hi all I understand that to calculate the standard error of correlation estimates converted into fishers z scores you need to follow - 1/(√N−3) Now I have the standard error , I am wondering how I calculate the variance please? Thanks
  7. L

    Converting spearmans r to fishers z for meta analysis ; Correcting for range in meta analysis

    Hi all I am conducting a meta analysis of pearsons r correlations but I have a study with a spearmans rank correlation. I was converting the pearsons correlations into fishers z scores to conduct the meta analysis , then to be converted back into correlations, but I am wondering if I am able to...
  8. J

    Meta-analysis using revman

    I was wondering if someone can help me with a meta-analysis using revman 5.3. I would like to switch from quadas to quadas2 but this link seems to be missing from the General tab. Has anyone had the same problem?
  9. S

    Average effect size between factors and within an experimental condition

    Dear all, I am interested in an average effect size between heart rate and anxiety. Anxiety is separated in 2 factors (F1 and F2), and I would like to combine the correlations of those factors into one correlation. In addition, I also have the correlations between heart rate and anxiety...
  10. R

    Comparing pooled data

    I have started a meta analysis comparing the complication rates of different treatments of distal radius fractures. I have pooled the complication rates (n/N) for each treatment separately using the inverse variance method, the DerSimonian-Laird estimator for tau^2, logit transformation...
  11. R

    Non-comparative studies in a meta-analysis

    I am currently busy with the statitics of a meta-analysis using non-comparative studies. Therefor I used the RevMan tool by Cochrane Initiative. But because the studies van non-comparative it does not work. I tried it in different ways, but I can't make it work. Can someone help me pool this...
  12. N

    Can I combine univariate and multivariate HR?

    Hi guys. I'm doing a meta-analysis of survival based on a blood marker, and not all the studies have provided a multivariate hazard ratio. Some have given a univariate hazard ratio (usually where it is not significant) and I would like to put them into the random effects analysis also. Should I...
  13. A

    Meta Analysis-Scales

    Hi, I am new into meta analysis and doing research on spirituality in organizations. I want to collect all scales and their results(on dimension base) about spiritual well-being and calculate each dimension's effect size. It seems to be some sort of literature review to me, is it meta...
  14. T

    Reporting participant numbers for meta analysis

    Hi there, I am hoping you may be able to help me with a query I have. I am conducting a meta analysis on Random Control Trials using REVMAN. I have secondary data I am trying to input.I wanted to know whether participants are added up in each condition if there are multiple trials or whether...
  15. G

    General inverse variance method

    Hi I hope I've posted this in the right place. I'm converting standardised mean differences to log OR for a meta-analysis. Just wanting to know can I combine log OR with the standard OR I have from papers? Or would I need to convert the OR's from papers into log ORs for analysis...
  16. B

    Appropriate p-value correction in two cohort meta-analysis (discovery / validation)

    Dear all, I would like to request your help and opinions on a meta-analysis setup utilizing two completely independent cancer cohorts, where one acts as discovery data set, while the other is meant as validation cohort. To 'integrate' both cohorts, I would like to select genes by FDR in...
  17. Y

    Coding Group Equivalency on Pre-Treatment Measures for Meta-Analysis?

    Hello- I am constructing a code book for a meta-analysis. I only want to include evaluations where program and comparison groups were reasonably well matched on pre-existing differences in key variables, such as age, prior educational achievement, etc. Any recommendations on what statistic to...
  18. S

    Suggestions for model fit with unusual data set?

    Good morning, I'm struggling to fit a satisfactory model to a data set I have resulting from a systematic review. I performed a systematic review of estimated $ valuations of grasslands and the services they provide. All grasslands provide all services, but some studies only value one of...
  19. M

    Preparing for Meta Analysis

    Hello Everybody, I am a physician and a researcher, have been studying the meta-analysis subject for a while now, and we are in the process to perform a metanalysis in the cardiology field in these days. Here it is a basic summary: although there are a lot of publications trying to...
  20. A

    Combining two ORs with the same control group

    Hi everybody. I am doing a meta-analysis of observational studies. As the disease I am working on has different stages, some of the studies reported ORs(95%CI) for each stage separately in comparison to a single (shared) control population. I wonder if we can combine these two ORs (and their...