methylation

Hi everyone, I was wondering whether you would be able to help me with ChAMP. I'm working on the software through R studio and having difficulty loading my data. A sample dataset came with the software and no matter what I do, the programme insists on referring back to this dataset rather than...

I have data on patient Age as well as change in % DNA methylation levels for promotor regions. I seek to understand the impact of Age on the % change in DNA methylation levels. What is the best way to do this? Paired t-test of Age vs % change in DNA methylation data yields ridiculously high...