randomized control trials

Hello, anyone out there familiar with Trial Sequential Analysis (TSA) software developed by Copenhagen Trial Unit? The free software is available at: http://www.ctu.dk/tsa/downloads.aspx Manual is available here: http://www.ctu.dk/tsa/files/tsa_manual.pdf Summary of my questions up here: 1. How...

I am analyzing data from a randomized clinical trial, with 2 intervention groups (placebo and intervention) and repeated measurements over time. I am planning to use linear mixed effects modeling to analyze this longitudinal data and determine whether the intervention causes a change in response...

I am designing an experiment in which the treatment is administered through information priming. I plan to conduct the experiment in a large city town. The town comprises of several blocks which are geographically contiguous. I plan to randomly pick four blocks and assign treatment (information...

I'm proposing to evaluate an outcome in three completed randomized controlled trials. The primary goal is to analyze a new outcome in each data set separately (i.e., 3 separate papers). A secondary aim is to compare across the three trials to see which intervention type was most effective...