May I ask a question on the trial sequential analysis (TSA)? It is a method of cumulative meta-analysis.
Could we pooled adjusted risk ratios (aRR) in trial sequential analysis, especially for observational studies in which there are obvious differences between crude RR and adjusted RR?
Hello, anyone out there familiar with Trial Sequential Analysis (TSA) software developed by Copenhagen Trial Unit?
The free software is available at: http://www.ctu.dk/tsa/downloads.aspx
Manual is available here: http://www.ctu.dk/tsa/files/tsa_manual.pdf
Summary of my questions up here: