My question is difficult to me,

I had read an article about how to calculate sample size

the foot note tole me"" ε = required absolute precision on either side of the sensitivity ""

what is the absolute precision means ?

and generally how to chose required absolute precision on either side of the sensitivity?

If the disease pre=10%

anticipiate sen=70% anticipiate spe=90%

chose Z1–α/2= 1.96 for =0.05.

how to define ε ? which numbers can i chose?

Thank you

sensitivity Z21-α SN(1-SN) ÷(ε2x Prev)

SAMPLE SIZE FORMULA FOR ESTIMATING SENSITIVITY AND SPECIFICITY AND AREA UNDER THE ROC CURVE

Estimating the sensitivity of test

SN =Anticipated sensitivity

Prev = Prevalence of disease in population can be obtained from previous literature or pilot study

ε = required absolute precision on either side of the sensitivity

I had read an article about how to calculate sample size

the foot note tole me"" ε = required absolute precision on either side of the sensitivity ""

what is the absolute precision means ?

and generally how to chose required absolute precision on either side of the sensitivity?

If the disease pre=10%

anticipiate sen=70% anticipiate spe=90%

chose Z1–α/2= 1.96 for =0.05.

how to define ε ? which numbers can i chose?

Thank you

sensitivity Z21-α SN(1-SN) ÷(ε2x Prev)

SAMPLE SIZE FORMULA FOR ESTIMATING SENSITIVITY AND SPECIFICITY AND AREA UNDER THE ROC CURVE

Estimating the sensitivity of test

SN =Anticipated sensitivity

Prev = Prevalence of disease in population can be obtained from previous literature or pilot study

ε = required absolute precision on either side of the sensitivity

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