Compare Ratios with difference underlying population sizes

Suppose my product is deployed to multiple regions and I want to compare if Daily Revenue(DR)/Daily Active Users(DAU) for US and Japan are the same.

Now I collect 14 data points(14 days, each day produce one data point) for US and Japan respectively.

However the DAU for US is ~1 Million and the DAU for Japan is ~100. Can I still use t-test formula to compare 2 ratios without considering underlying DAU/DR huge difference?


Not a robit
Can you better show us what your data look like? Are you looking to plot to time series and compare slopes or look at daily differences? More information is needed.