Comparison and visualization of multiple output data files

#1
I have 100 data files corresponding to 100 samples. For these 100 data files, I have processed data in 4 different ways to generate result output files.

Out of the 4 results files per sample, I would like to consider one of these files as a true result. Now I want to compare the other 3 output files for each sample to see how did each processing method perform as compared to the true result method. For individual samples I was able to see the performance using a Venn diagram. But this leads to 100 Venn diagrams. Can someone suggest me a better method to evaluate and visualize the performance/ compare the output files in this case?

The output files basically contain a list of chemical compounds detected by each method.

Not sure if a ROC curve would be useful in this case?