I'm trying to perform Cox regression on a data set with multiple random missing values. SPSS is my go-to software, but the Cox regression algorithm applies LISTWISE deletion to all cases with missing values, resulting in omission of >30% of the cases. I'd rather it used PAIRWISE deletion, but can't seem to find that option. I usually use the GUI but have some basic coding experience; tinkering with the code, however, has so far proved fruitless. I have the impression, from SPSS documentation, that LISTWISE deletion is built into the Cox regression algorithm.

In the past week, I have been trying to get to grips with SAS as an alternative. So far as I can tell, PROC PHREG is not available via SAS-Studio, so I shall have to learn SAS coding if I want to go any further.

My questions are: (1) will SAS allow me to perform Cox regression with pairwise deletion of missing values (as opposed to omission of all cases with missing values)? If so, then it is worth my while learning how to code. If not, then I'd rather not waste time reinventing the wheel...

(2) Alternatively, is there a way to perform Cox regression on SPSS with pairwise rather than listwise deletion?

(3) Could someone recommend any alternative software that will allow me to perform Cox regression with missing values (without listwise deletion of cases)?

I realise there are imputation procedures available for missing values in both SPSS and SAS, but wish to use them only as a last resort (owing to the nature of the data).

I'd really appreciate any help.