GUI software for GLM

#1
I am analyzing a scRNAseq data trying to follow a protocol suggested in this paper- https://www.nature.com/articles/nature24489 mentioned under Computational analysis The statement reads- " Selection of variable genes was performed by fitting a generalized linear model to the relationship between the squared coefficient of variation and the mean expression level in logarithmic space, and selecting genes that deviated significantly (P < 0.05) from the fitted curve"
  1. What is the best GUI based software or an R package that can fit the model for multiple columns data and out put p value for each cell row (gene).

Thanks
 
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