Cell biologist in need of stats help!

I am using stata to analyse my data and have two questions:

1. I have a continuous outcome (hippocampal volume) and exposures grouped either as categorical (4 levels) or binary. Is linear regression an appropriate analysis for this data?

2. When I construct basic scatter plots between my exposure and outcome, there looks to be no or very little correlation. Am I right in assuming you need to see some kind of relationship to conduct linear regression? In that case, is there anything I can do to my data to allow me to analyse it?

I have many covariates that need to be considered- I am not sure if going straight ahead and running models to adjust for age, sex etc would be useful.... All online sources seem to imply you must see a linear relationship between E -> O to conduct linear regression :/

Any advice would be gratefully received

I am using stata to analyse my data and have two questions:

1. I have a continuous outcome (hippocampal volume) and exposures grouped either as categorical (4 levels) or binary. Is linear regression an appropriate analysis for this data?

2. When I construct basic scatter plots between my exposure and outcome, there looks to be no or very little correlation. Am I right in assuming you need to see some kind of relationship to conduct linear regression? In that case, is there anything I can do to my data to allow me to analyse it?

I have many covariates that need to be considered- I am not sure if going straight ahead and running models to adjust for age, sex etc would be useful.... All online sources seem to imply you must see a linear relationship between E -> O to conduct linear regression :/

Any advice would be gratefully received

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