hi from Kent, UK

[meursault]

NHS scientist looking for advice and ideas with method validation stats

and maybe getting started with R if i'm feeling brave....

 

[hlsmith]

Hello!


Can you define NHS and talk about what types of methods you use as well.


Welcome aboard.

 

[noetsi]

I am guessing it is national health service

https://en.wikipedia.org/wiki/National_Health_Service

What do you mean by method validation stats? Test of the assumptions of a given method? If so I have done lots and lots of threads on that recently

 

[hlsmith]

I was thinking approaches like cross-validation.

 

[Outlier]

http://www.google.com/search?client=safari&rls=en&q=meursault+camus&ie=UTF-8&oe=UTF-8

Any connection?

 

[noetsi]

Not an encouraging figure for a medical researcher

 

[meursault]

haha yes, an excellent novel and i've always liked 'the outsider' as a forum user name

 

[meursault]

I am guessing it is national health service

https://en.wikipedia.org/wiki/National_Health_Service

What do you mean by method validation stats? Test of the assumptions of a given method? If so I have done lots and lots of threads on that recently

method comparison using bland-altman etc

precision including repeatibility and reproducibility

linearity

stability

mainly verification of a new assay on an analyser or of an existing assay on a new analyser

a lot of this is covered by CLSI protocols, especially EP15-A3 for which Analyse-it provides support, but it's very expensive so i was looking into using R

 

[noetsi]

We have a solid group of R experts (aka fanatics) on this board so you probably could get suggestions on if this exists in R.

 

[alexhalesperry]

Is their Anyone can give a guidance to me ?

 

[rogojel]

hi,
these are questions that are frequently looked at in six sigma under the hood of measurement system analysis. So, fire away!