How to regress data

Hi, I would like to do a simple regression one variable on a dependent variable. Specifically, I would like to regress a financial ratio such as ROE on stock returns. I have a panel dataset with some companies missing years. It is an unbalanced panel dataset. Can I just run a normal regression? Or do I need to do a panel data method? I am currently using STATA, I am unsure whether to use the normal regress dep ind or xtreg dep ind function. I am terrible at statistics and not quite sure what to use. I have attached a small sample of my dataset. Any help is gratefully appreciated.