Require advise !!

hi..i have a cohort of clinical samples which has many parameters like age, sex, clinical grade etc...for each clinical samples, i have five different protein expression...i want to know the statistical significance of each protein to different clinical parameters, what test do i do for that? and i also want to compare the expression among the different proteins and associate it with the clinical parameters. what test do i do for that? Hope my question is clear. help is much appreciated