Tukey kramer


I am applying Tukey Kramer on a data problem. Actually, there are 5 treatments that i want to compare and 1 is control. Out of 5 treatments, 1 treatment value is closer to control. The value of response for 4 treatments ranges between 50-400. Control and other treatment value ranges between 2200-2800. When I apply Tukey kramer on all 6 treatments, there is no significance between 4 low value treatments but they are significant from other 2 treatments. When I performed Tukey Kramer on other 4 low value treatments, there shows a significance among the treatments. The data is variable over time. Is it possible? I would really appreciate any help and suggestions, please. I am defending soon and have to add the analysis into it. Thanks in advance for any help.