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    [Python] - dealing with large text files

    Hi, I have a large file (2 GB) with 4 columns that I want to read and extract some info from. The data looks like this: CHR START END A 1 10583 10583 0.14 1 10611 10611 0.02 1 13302 13302 0.11 I also have another file from where I have extracted a string to be compared with...
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    Fisher's exact test, Hypergeometric distribution

    Hi, I need some help with Fisher's exact test and the hypergeometric distribution My data consists of: 500 mutations - that I want to score as either damaging or benign 500 population allele frequencies (AF) - extracted, for each mutation, from a set of 10 000 controls For each...