Combinatorial Analysis HW Help

There are 100 U.S Senators, two from each of the 50 States.

If 12 Senators are randomly chosen to form a committee, what is the probabilty that they are alll from different states?

If 12 senators are chosen at random from the 100 senators, what is the probabilty that neither of the two senators from Florida is in the committee?

I have absolutely no idea how to begin this problem.